Association between Serum Alkaline Phosphatase and Primary Resistance to Erythropoiesis Stimulating Agents in Chronic Kidney Disease: A Secondary Analysis of the HERO Trial

• Published in: Canadian journal of kidney health and disease Vol. 2; p. 33
• Main Authors: Badve, Sunil V., Zhang, Lei, Coombes, Jeff S., Pascoe, Elaine M., Cass, Alan, Clarke, Philip, Ferrari, Paolo, McDonald, Stephen P., Morrish, Alicia T., Pedagogos, Eugenie, Perkovic, Vlado, Reidlinger, Donna, Scaria, Anish, Walker, Rowan, Vergara, Liza A., Hawley, Carmel M., Johnson, David W.
• Format: Journal Article
• Language: English
• Published: Los Angeles, CA SAGE Publications 2015; Sage Publications Ltd; BioMed Central; SAGE Publishing
• Subjects: Anemia; Enzymes; Kidney diseases; Original; Oxidative stress; Phosphatase; Alkaline phosphatase; Anemia; Biological marker; Erythropoiesis stimulating agents; Chronic kidney disease; Randomized controlled trial; Risk factors

Background: Erythropoiesis stimulating agent (ESA)-resistant anemia is common in chronic kidney disease (CKD). Objectives: To evaluate the determinants of severity of ESA resistance in patients with CKD and primary ESA-resistance. Design: Secondary analysis of a randomized controlled trial (the Hand...