Oral methotrexate in ulcerative colitis

• Published in: Alimentary pharmacology & therapeutics Vol. 21; no. 4; pp. 385 - 389
• Main Authors: Cummings, J. R. F., Herrlinger, K. R., Travis, S. P. L., Gorard, D. A., McIntyre, A. S., Jewell, D. P.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Ltd 15.02.2005; Blackwell
• Subjects: Adolescent; Adult; Aged; Antirheumatic Agents - therapeutic use; Arthritis, Rheumatoid - complications; Arthritis, Rheumatoid - drug therapy; Azathioprine - adverse effects; Biological and medical sciences; Colitis, Ulcerative - complications; Colitis, Ulcerative - drug therapy; Digestive system; Female; Gastroenterology. Liver. Pancreas. Abdomen; Gastrointestinal Agents - adverse effects; Gastrointestinal Agents - therapeutic use; Humans; Immunosuppressive Agents - adverse effects; Immunosuppressive Agents - therapeutic use; Male; Medical sciences; Methotrexate - adverse effects; Methotrexate - therapeutic use; Middle Aged; Pharmacology. Drug treatments; Retrospective Studies; Treatment Outcome; Antifolate; Antineoplastic agent; Antimetabolic; Oral administration; Digestive diseases; Intestinal disease; Methotrexate; Inflammatory disease; Ulcerative colitis

Summary Background : We performed an audit of methotrexate for ulcerative colitis, because efficacy is unclear. Aim : To investigate the role of methotrexate in the management of ulcerative colitis. Methods : Patients with ulcerative colitis treated with oral methotrexate at the inflammatory bowel d...