In vivo measurement of shear modulus of the human cornea using optical coherence elastography

• Published in: Scientific reports Vol. 10; no. 1; p. 17366
• Main Authors: Ramier, Antoine, Eltony, Amira M., Chen, YiTong, Clouser, Fatima, Birkenfeld, Judith S., Watts, Amy, Yun, Seok-Hyun
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 15.10.2020
• Subjects: 631/1647/245/2226; 639/301/923/1029; 639/624/1111/55; Adult; Aged; Cornea - diagnostic imaging; Elasticity Imaging Techniques - methods; Humanities and Social Sciences; Humans; Middle Aged; multidisciplinary; Pilot Projects; Science; Science (multidisciplinary); Stress, Mechanical; Tomography, Optical Coherence - methods

Corneal stiffness plays a critical role in shaping the cornea with respect to intraocular pressure and physical interventions. However, it remains difficult to measure the mechanical properties noninvasively. Here, we report the first measurement of shear modulus in human corneas in vivo using optic...