The effect of insulin-induced hypoglycemia on inflammatory markers: A systematic review

• Published in: Brain, behavior, and immunity Vol. 73; pp. 41 - 50
• Main Authors: Drummond, Juliana B., Barbosa, Izabela G., Dantzer, Robert, Teixeira, Antonio L.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.10.2018
• Subjects: Biomarkers - blood; Biomarkers - metabolism; Blood Glucose - metabolism; Diabetes Mellitus - metabolism; Diabetes Mellitus, Type 1 - metabolism; Female; Humans; Hypoglycemia; Hypoglycemia - metabolism; Inflammation; Inflammation - metabolism; Insulin; Insulin - metabolism; Insulin - physiology; Male; Sympathetic Nervous System - metabolism; Hypoglycemia; Insulin; Inflammation

•Acute hypoglycaemia induces a pro-inflammatory state.•Elevation of inflammatory markers occurs in both type-1 and non-diabetic subjects.•Activation of the sympathetic nervous system is a likely mediator of these effects. The effects of acute hypoglycemia on markers of inflammation have been investi...