Massively-multiplexed epitope mapping techniques for viral antigen discovery

• Published in: Frontiers in immunology Vol. 14; p. 1192385
• Main Authors: Hu, Diya, Irving, Aaron T.
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 25.09.2023
• Subjects: B cell; epitope; epitope mapping; Immunology; phage-display; T cell

Following viral infection, viral antigens bind specifically to receptors on the surface of lymphocytes thereby activating adaptive immunity in the host. An epitope, the smallest structural and functional unit of an antigen, binds specifically to an antibody or antigen receptor, to serve as key sites...