ACE2 gene combined with exercise training attenuates central AngII/AT1 axis function and oxidative stress in a prehypertensive rat model - Chen, Xiu-Yun; Lin, Cheng; Liu, Guo-Ying; Pei, Chun; Xu, Gui-Qing; Gao, Lie; Wang, Shi-Zhong; Pan, Yan-Xia (Journal of applied physiology (1985), 2022)
Keywords: ACE2; ACE2 gene; Angiotensin; Angiotensin I - metabolism; Angiotensin II; Angiotensin II - metabolism; Angiotensin-converting enzyme 2; Angiotensin-Converting Enzyme 2 - metabolism; Animal models; Animals; Baroreceptors; Blood Pressure; CYBB protein; Fitness training programs; Fluorescence; Green fluorescent protein; Hypertension; Hypertension - metabolism; Hypertension - therapy; Male; NAD(P)H oxidase; Norepinephrine; NOX4 protein; Oxidative stress; Oxidative Stress - physiology; Paraventricular Hypothalamic Nucleus; Paraventricular nucleus; Peptidyl-dipeptidase A; Physical Conditioning, Animal - physiology; Physical training; Prehypertension - metabolism; Pressure effects; Protein expression; Proteins; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reactive oxygen species; Reflexes; baroreflex; hypertension; renin-angiotensin system; exercise training; paraventricular nucleus