Beyond apples and pears: sex-specific genetics of body fat percentage

• Published in: Frontiers in endocrinology (Lausanne) Vol. 14; p. 1274791
• Main Authors: Roshandel, Delnaz, Lu, Tianyuan, Paterson, Andrew D., Dash, Satya
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 05.10.2023
• Subjects: body fat percentage; Endocrinology; genome-wide association study; obesity; sex hormone binding globulin; testosterone

Biological sex influences both overall adiposity and fat distribution. Further, testosterone and sex hormone binding globulin (SHBG) influence adiposity and metabolic function, with differential effects of testosterone in men and women. Here, we aimed to perform sex-stratified genome-wide associatio...