Carotid artery intima-media thickness correlates with oxidative stress in chronic haemodialysis patients with accelerated atherosclerosis

• Published in: Nephrology, dialysis, transplantation Vol. 23; no. 5; pp. 1697 - 1703
• Main Authors: Dursun, Belda, Dursun, Evrim, Suleymanlar, Gultekin, Ozben, Beste, Capraz, Irfan, Apaydin, Ali, Ozben, Tomris
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.05.2008; Oxford Publishing Limited (England)
• Subjects: Aged; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Atherosclerosis - blood; Atherosclerosis - diagnostic imaging; Atherosclerosis - etiology; Atherosclerosis - pathology; Biological and medical sciences; Biomarkers - blood; Carotid Arteries - diagnostic imaging; Carotid Arteries - pathology; carotid artery intima media thickness; Case-Control Studies; Catalase - blood; chronic haemodialysis patients; Emergency and intensive care: renal failure. Dialysis management; Erythrocytes - metabolism; Female; Glutathione - blood; Glutathione Peroxidase - blood; Humans; Intensive care medicine; Male; Medical sciences; Middle Aged; Nephrology. Urinary tract diseases; Nephropathies. Renovascular diseases. Renal failure; Nitrates - blood; Nitrites - blood; Oxidative Stress; Renal Dialysis - adverse effects; Renal failure; Sulfhydryl Compounds - blood; Superoxide Dismutase - blood; Thiobarbituric Acid Reactive Substances - metabolism; Tunica Intima - diagnostic imaging; Tunica Intima - pathology; Ultrasonography; Uremia - blood; Uremia - complications; Uremia - pathology; carotid artery intima media thickness; oxidative stress; chronic haemodialysis patients; Kidney disease; Human; Oxidative stress; Urinary system disease; Hemodialysis; Cardiovascular disease; Vascular disease; Extrarenal dialysis; Carotid; Atherosclerosis; Renal failure

Background. Accelerated atherosclerosis is the major cause of mortality in patients on chronic haemodialysis (HD). Increased oxidative stress might be the major factor leading to high cardiovascular mortality rate in HD patients. The aim of our study was to clarify effects of uraemia and dialysis on...