C500 variants conveying complete mucosal immunity against fatal infections of pigs with Salmonella enterica serovar Choleraesuis C78-1 or F18+ Shiga toxin-producing Escherichia coli

• Published in: Frontiers in microbiology Vol. 14; p. 1210358
• Main Authors: Liu, Guoping, Li, Chunqi, Liao, Shengrong, Guo, Aizhen, Wu, Bin, Chen, Huanchun
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 14.09.2023
• Subjects: edema disease of swine; host; in vivo; Microbiology; mucosal immunity; Salmonella enterica serovar Choleraesuis C500

Salmonella enterica serovar Choleraesuis ( S. Choleraesuis) C500 strain is a live, attenuated vaccine strain that has been used in China for over 40 years to prevent piglet paratyphoid. However, this vaccine is limited by its toxicity and does not offer protection against diseases caused by F18+ Shi...