Identification and expression of an autosomal paralogue of ribosomal protein S4, X-linked, in mice: Potential involvement of testis-specific ribosomal proteins in translation and spermatogenesis

• Published in: Gene Vol. 521; no. 1; pp. 91 - 99
• Main Authors: Sugihara, Yoshihiko, Sadohara, Eiji, Yonezawa, Kahori, Kugo, Mariko, Oshima, Kenzi, Matsuda, Tsukasa, Nadano, Daita
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 25.05.2013
• Subjects: Amino Acid Sequence; Animals; evolution; Gene Expression; genes; Genes, X-Linked; homeostasis; Humans; Male; Mammalian ribosome; messenger RNA; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Mouse testis; Organ Specificity; Paralogue; polyribosomes; Polyribosomes - metabolism; Polysome; protein composition; proteomics; Ribosomal protein; ribosomal proteins; Ribosomal Proteins - genetics; Ribosomal Proteins - immunology; Ribosomal Proteins - metabolism; Spermatogenesis; Spermatogenesis - genetics; surveys; testes; Testis - physiology; translation (genetics); RT; SDS; Spermatogenesis; MS; PMF; PAGE; TOF; Mouse testis; MS/MS; Ribosomal protein; GFP; Paralogue; NCBI; RFHR; Mammalian ribosome; S4Y2; Polysome; GAPDH; PCR; S4Y1

Recent studies have revealed heterogeneity in the structure of eukaryotic cytoplasmic ribosomes, including a difference in protein composition. It has been proposed that this heterogeneity, or the specialized ribosome, contributes to tissue development and homeostasis through selective mRNA translat...