Dietary supplementation with proline confers a positive effect in both porcine circovirus-infected pregnant and non-pregnant mice

• Published in: British journal of nutrition Vol. 110; no. 8; pp. 1492 - 1499
• Main Authors: Ren, Wenkai, Wu, Miaomiao, Luo, Wei, Huang, Ruilin, Yin, Yulong, Li, Yinghui, Li, Teijun, yu, Xinglong
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 28.10.2013
• Subjects: Abortion, Spontaneous; Amino acids; Animal diseases; Animals; Biological and medical sciences; C-Reactive Protein - metabolism; Circoviridae Infections - immunology; Circoviridae Infections - prevention & control; Circovirus; Cytokines - blood; Dietary Supplements; Dietary Surveys and Nutritional Epidemiology; Feeding. Feeding behavior; Female; Fundamental and applied biological sciences. Psychology; Immune response; Immune system; Lesions; Lymphocytes; Mice; Nutrition; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious - immunology; Pregnancy Complications, Infectious - virology; Pregnancy, Animal; Proline - therapeutic use; Random Allocation; Vertebrates: anatomy and physiology, studies on body, several organs or systems; Viral Load; Proline; Porcine circovirus type 2; Nutritional regulations; Functional amino acids; Porcine circovirus-associated diseases; Nutrition; Rodentia; Feeding; Pig; Pregnancy; Infection; Vertebrata; Regulation(control); Mammalia; Mouse; Proline: Nutritional regulations; Aminoacid; Animal; Artiodactyla; Supplementation; Ungulata

Porcine circovirus type 2 (PCV2) is associated with various diseases that impose a significant economic burden on the swine industry. We hypothesised that nutritional supplementation with proline to enhance the immune response might be a useful prophylactic measure against PCV2 infection. To test th...