Does wastewater treatment plant upgrading with activated carbon result in an improvement of fish health?

•Incomplete removal of micropollutants by conventional wastewater treatment.•Efficiency of an additional powdered activated carbon filter unit was investigated.•Biomarker responses in fish were correlated with results of chemical analyses.•After WWTP upgrade, micropollutant levels and adverse effect...

Full description

Saved in:
Bibliographic Details
Published inAquatic toxicology Vol. 192; pp. 184 - 197
Main Authors Wilhelm, Sabrina, Henneberg, Anja, Köhler, Heinz-R., Rault, Magali, Richter, Doreen, Scheurer, Marco, Suchail, Séverine, Triebskorn, Rita
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.11.2017
Elsevier
Subjects
Online AccessGet full text

Cover

Loading…
Abstract •Incomplete removal of micropollutants by conventional wastewater treatment.•Efficiency of an additional powdered activated carbon filter unit was investigated.•Biomarker responses in fish were correlated with results of chemical analyses.•After WWTP upgrade, micropollutant levels and adverse effects in fish were reduced. In the present study, the efficiency of a wastewater treatment plant (WWTP) upgraded with a powdered activated carbon unit for the reduction of micropollutants and the related advantages for fish health have been analyzed by means of different biomarkers, i.e. histopathological investigations, analyses of glycogen content and stress proteins, as well as by chemical analyses in different matrices. Comparative analyses were conducted prior and subsequent to the installation of the additional purification unit. Chemical analyses revealed a significant reduction of several pharmaceuticals, including diclofenac, carbamazepine and metoprolol, in samples of effluent and surface water downstream of the WWTP after its upgrade. In addition, diminished concentrations of diclofenac and PFOS were detected in tissues of analyzed fish. Histopathological investigations of fish liver, gills, and kidney revealed improved tissue integrity in fish after improved wastewater treatment. In parallel, biochemical measurements of glycogen revealed increased energy resources in fish liver and, furthermore, hsp70 levels in livers of exposed rainbow trout and in kidneys of exposed brown trout were lower after than before the WWTP upgrade. In summary, additional treatment with powdered activated carbon led to a reduction of potentially hazardous chemicals in the effluent and the adjacent river and, consequently, to an improvement of fish health in the receiving water course.
AbstractList In the present study, the efficiency of a wastewater treatment plant (WWTP) upgraded with a powdered activated carbon unit for the reduction of micropollutants and the related advantages for fish health have been analyzed by means of different biomarkers, i.e. histopathological investigations, analyses of glycogen content and stress proteins, as well as by chemical analyses in different matrices. Comparative analyses were conducted prior and subsequent to the installation of the additional purification unit. Chemical analyses revealed a significant reduction of several pharmaceuticals, including diclofenac, carbamazepine and metoprolol, in samples of effluent and surface water downstream of the WWTP after its upgrade. In addition, diminished concentrations of diclofenac and PFOS were detected in tissues of analyzed fish. Histopathological investigations of fish liver, gills, and kidney revealed improved tissue integrity in fish after improved wastewater treatment. In parallel, biochemical measurements of glycogen revealed increased energy resources in fish liver and, furthermore, hsp70 levels in livers of exposed rainbow trout and in kidneys of exposed brown trout were lower after than before the WWTP upgrade. In summary, additional treatment with powdered activated carbon led to a reduction of potentially hazardous chemicals in the effluent and the adjacent river and, consequently, to an improvement of fish health in the receiving water course.
In the present study, the efficiency of a wastewater treatment plant (WWTP) upgraded with a powdered activated carbon unit for the reduction of micropollutants and the related advantages for fish health have been analyzed by means of different biomarkers, i.e. histopathological investigations, analyses of glycogen content and stress proteins, as well as by chemical analyses in different matrices. Comparative analyses were conducted prior and subsequent to the installation of the additional purification unit. Chemical analyses revealed a significant reduction of several pharmaceuticals, including diclofenac, carba-mazepine and metoprolol, in samples of effluent and surface water downstream of the WWTP after its upgrade. In addition, diminished concentrations of diclofenac and PFOS were detected in tissues of analyzed fish. Histopathological investigations of fish liver, gills, and kidney revealed improved tissue integrity in fish after improved wastewater treatment. In parallel, biochemical measurements of glycogen revealed increased energy resources in fish liver and, furthermore, hsp70 levels in livers of exposed rainbow trout and in kidneys of exposed brown trout were lower after than before the WWTP upgrade. In summary, additional treatment with powdered activated carbon led to a reduction of potentially hazardous chemicals in the effluent and the adjacent river and, consequently, to an improvement of fish health in the receiving water course.
•Incomplete removal of micropollutants by conventional wastewater treatment.•Efficiency of an additional powdered activated carbon filter unit was investigated.•Biomarker responses in fish were correlated with results of chemical analyses.•After WWTP upgrade, micropollutant levels and adverse effects in fish were reduced. In the present study, the efficiency of a wastewater treatment plant (WWTP) upgraded with a powdered activated carbon unit for the reduction of micropollutants and the related advantages for fish health have been analyzed by means of different biomarkers, i.e. histopathological investigations, analyses of glycogen content and stress proteins, as well as by chemical analyses in different matrices. Comparative analyses were conducted prior and subsequent to the installation of the additional purification unit. Chemical analyses revealed a significant reduction of several pharmaceuticals, including diclofenac, carbamazepine and metoprolol, in samples of effluent and surface water downstream of the WWTP after its upgrade. In addition, diminished concentrations of diclofenac and PFOS were detected in tissues of analyzed fish. Histopathological investigations of fish liver, gills, and kidney revealed improved tissue integrity in fish after improved wastewater treatment. In parallel, biochemical measurements of glycogen revealed increased energy resources in fish liver and, furthermore, hsp70 levels in livers of exposed rainbow trout and in kidneys of exposed brown trout were lower after than before the WWTP upgrade. In summary, additional treatment with powdered activated carbon led to a reduction of potentially hazardous chemicals in the effluent and the adjacent river and, consequently, to an improvement of fish health in the receiving water course.
Author Richter, Doreen
Wilhelm, Sabrina
Henneberg, Anja
Triebskorn, Rita
Köhler, Heinz-R.
Scheurer, Marco
Suchail, Séverine
Rault, Magali
Author_xml – sequence: 1
  givenname: Sabrina
  surname: Wilhelm
  fullname: Wilhelm, Sabrina
  email: sabrina_wilhelm@live.de
  organization: Animal Physiological Ecology, University of Tübingen, Auf der Morgenstelle 5, D-72076 Tübingen, Germany
– sequence: 2
  givenname: Anja
  surname: Henneberg
  fullname: Henneberg, Anja
  email: anja.henneberg@gmail.com
  organization: Animal Physiological Ecology, University of Tübingen, Auf der Morgenstelle 5, D-72076 Tübingen, Germany
– sequence: 3
  givenname: Heinz-R.
  surname: Köhler
  fullname: Köhler, Heinz-R.
  email: heinz-r.koehler@uni-tuebingen.de
  organization: Animal Physiological Ecology, University of Tübingen, Auf der Morgenstelle 5, D-72076 Tübingen, Germany
– sequence: 4
  givenname: Magali
  surname: Rault
  fullname: Rault, Magali
  email: magali.rault@univ-avignon.fr
  organization: Institut Méditerranéen de Biodiversité et d’Ecologie Marine et Continentale, IMBE UAPV AMU IRD, Pôle Agrosciences, BP 21239, 84916 Avignon, France
– sequence: 5
  givenname: Doreen
  surname: Richter
  fullname: Richter, Doreen
  email: doreen.richter@tzw.de
  organization: DVGW Water Technology Center, Karlsruher Straße 84, D-76139 Karlsruhe, Germany
– sequence: 6
  givenname: Marco
  surname: Scheurer
  fullname: Scheurer, Marco
  email: marco.scheurer@tzw.de
  organization: DVGW Water Technology Center, Karlsruher Straße 84, D-76139 Karlsruhe, Germany
– sequence: 7
  givenname: Séverine
  surname: Suchail
  fullname: Suchail, Séverine
  email: severine.suchail@univ-avignon.fr
  organization: Institut Méditerranéen de Biodiversité et d’Ecologie Marine et Continentale, IMBE UAPV AMU IRD, Pôle Agrosciences, BP 21239, 84916 Avignon, France
– sequence: 8
  givenname: Rita
  surname: Triebskorn
  fullname: Triebskorn, Rita
  email: rita.triebskorn@uni-tuebingen.de, stz.oekotox@gmx.de
  organization: Animal Physiological Ecology, University of Tübingen, Auf der Morgenstelle 5, D-72076 Tübingen, Germany
BackLink https://www.ncbi.nlm.nih.gov/pubmed/28965022$$D View this record in MEDLINE/PubMed
https://univ-avignon.hal.science/hal-02047744$$DView record in HAL
BookMark eNqFkE9v2yAYh9HUaU3bfYRWXHewBwSMOVVVu_6RIu2ySb0hDK9rIsd4QJLt2480Xa_jwA-h5wG9vzN0MoUJELqkpKaENl_Xtfm1NTn8rhmhsiaqLvEBLWgrVUUF5SdoUbim4lw8n6KzlNakLMbVJ3TKWtUIwtgCDXcBEt6blGFvMkScI5i8gSnjeTRl384v0Tg_veC9zwM2NvtdAR22JnZhwhHSdszYT9hM2G_mGHbwqoce9z4NeAAz5uH6An3szZjg81ueo5_3337cPlar7w9PtzerynLe5KrrOk6lsapxFhghqnPlCKKMYgWXjiplexBKMJC9JCBF03btUrVsyayVbnmOvhzfHcyo5-g3Jv7RwXj9eLPShzvCCJeS8x0trDiyNoaUIvTvAiX60LJe67eW9aFlTZQuUbyrozdvuw24d-tfrQW4PgJQJt15iDpZD5MF5yPYrF3w__niL4hmlCw
CitedBy_id crossref_primary_10_1016_j_scitotenv_2022_155912
crossref_primary_10_1016_j_envpol_2023_123075
crossref_primary_10_1016_j_scitotenv_2021_150020
crossref_primary_10_1002_etc_5849
crossref_primary_10_1007_s12011_021_02855_3
crossref_primary_10_1088_1757_899X_962_4_042094
crossref_primary_10_1186_s12302_019_0267_0
crossref_primary_10_1186_s12302_021_00584_x
crossref_primary_10_1039_D1TA02251B
crossref_primary_10_1016_j_ecoenv_2019_03_030
crossref_primary_10_3390_ma15113850
crossref_primary_10_1016_j_aquatox_2022_106375
crossref_primary_10_1007_s10646_023_02663_6
crossref_primary_10_1007_s10661_020_08515_8
crossref_primary_10_1016_j_envpol_2020_114478
crossref_primary_10_1186_s12302_018_0154_0
crossref_primary_10_1021_acs_est_9b00570
crossref_primary_10_1016_j_jhazmat_2019_121441
crossref_primary_10_1007_s11356_019_06032_x
crossref_primary_10_1021_acs_chemrev_9b00797
Cites_doi 10.1007/s00216-006-1033-x
10.1016/j.watres.2014.08.050
10.1186/2190-4715-25-2
10.3354/dao044161
10.1016/j.jhazmat.2016.03.096
10.1007/s00244-016-0310-8
10.1016/0044-8486(93)90395-F
10.1016/j.aquatox.2011.07.017
10.1016/j.chemosphere.2014.06.066
10.1016/j.scitotenv.2017.07.042
10.1016/j.aquatox.2014.10.017
10.1016/j.cbpa.2015.03.009
10.1007/s11356-016-6445-3
10.1016/j.physbeh.2016.06.033
10.1007/s10646-016-1694-y
10.1016/j.aquaculture.2004.02.025
10.1515/revce-2015-0034
10.1023/B:WATE.0000009889.36833.c0
10.1007/s10661-007-9886-9
10.1006/eesa.1997.1595
10.1023/A:1018682928839
10.1016/S0378-1119(02)00687-X
10.1016/0003-2697(76)90527-3
10.1289/ehp.877147
10.1016/j.envsci.2012.10.002
10.1111/j.1095-8649.1982.tb03895.x
10.1016/j.foodchem.2014.11.018
10.1016/0022-2836(74)90447-1
10.1023/A:1012935931161
10.1098/rspb.2015.3078
10.1016/j.ecoenv.2016.01.005
10.1016/j.watres.2016.03.009
10.1007/s002440010184
10.1007/s11270-014-1877-1
10.1016/j.landusepol.2008.08.005
10.17560/gwfwa.v157i04.1783
10.1242/jeb.140665
10.1016/j.scitotenv.2017.03.203
10.1016/j.aquatox.2017.05.017
10.1023/A:1008212000208
10.1016/j.aquatox.2004.03.015
10.1126/science.1127291
10.1016/j.watres.2016.04.069
10.1006/abio.1997.2138
10.1023/A:1012958804442
10.1139/cjfas-2016-0074
10.1016/j.aquatox.2012.12.021
10.1002/wat2.1090
10.1016/S0147-6513(03)00073-3
10.1007/s11356-014-3785-8
10.1023/A:1021009418421
10.1371/journal.pone.0098307
10.1016/j.watres.2016.01.009
10.1016/j.chnaes.2014.07.006
10.1016/0166-445X(90)90041-M
10.1111/j.1095-8649.1989.tb03355.x
10.1023/A:1008224301117
10.1039/c2em30037k
10.1002/jez.10126
10.1016/j.ecoenv.2016.04.036
10.1002/tox.22026
10.1007/s11270-016-2769-3
10.1046/j.1461-0248.2003.00528.x
10.1590/S1679-62252007000300013
10.1016/j.nbt.2014.01.001
10.1016/j.chemosphere.2008.05.062
10.3748/wjg.v11.i14.2072
10.1016/j.chemosphere.2008.09.075
10.1016/j.ijsrc.2016.03.001
ContentType Journal Article
Copyright 2018 The Authors
Copyright © 2017. Published by Elsevier B.V.
Distributed under a Creative Commons Attribution 4.0 International License
Copyright_xml – notice: 2018 The Authors
– notice: Copyright © 2017. Published by Elsevier B.V.
– notice: Distributed under a Creative Commons Attribution 4.0 International License
DBID 6I.
AAFTH
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
1XC
VOOES
DOI 10.1016/j.aquatox.2017.09.017
DatabaseName ScienceDirect Open Access Titles
Elsevier:ScienceDirect:Open Access
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
CrossRef
Hyper Article en Ligne (HAL)
Hyper Article en Ligne (HAL) (Open Access)
DatabaseTitle MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
CrossRef
DatabaseTitleList MEDLINE


Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
DeliveryMethod fulltext_linktorsrc
Discipline Chemistry
Ecology
Environmental Sciences
EISSN 1879-1514
EndPage 197
ExternalDocumentID oai_HAL_hal_02047744v1
10_1016_j_aquatox_2017_09_017
28965022
S0166445X17302655
Genre Journal Article
GroupedDBID ---
--K
--M
-~X
.~1
0R~
1B1
1RT
1~.
1~5
23M
4.4
457
4G.
53G
5GY
5VS
6I.
6J9
6TJ
7-5
71M
8P~
9JM
AABNK
AABVA
AACTN
AAEDT
AAEDW
AAFTH
AAIAV
AAIKJ
AAKOC
AALCJ
AALRI
AAOAW
AAQFI
AAQXK
AATLK
AAXUO
ABFNM
ABFRF
ABGRD
ABJNI
ABMAC
ABXDB
ABYKQ
ACDAQ
ACGFO
ACGFS
ACIUM
ACRLP
ADBBV
ADEZE
ADMUD
ADQTV
AEBSH
AEFWE
AEKER
AENEX
AEQOU
AFKWA
AFTJW
AFXIZ
AGHFR
AGUBO
AGYEJ
AHHHB
AIEXJ
AIKHN
AITUG
AJBFU
AJOXV
ALMA_UNASSIGNED_HOLDINGS
AMFUW
AMRAJ
ASPBG
AVWKF
AXJTR
AZFZN
BKOJK
BLXMC
CBWCG
CS3
EBS
EFJIC
EFLBG
EJD
EO8
EO9
EP2
EP3
F5P
FDB
FEDTE
FGOYB
FIRID
FNPLU
FYGXN
G-2
G-Q
GBLVA
HLV
HMC
HMT
HVGLF
HZ~
IHE
J1W
KOM
LW9
LY9
M34
M41
MO0
N9A
O-L
O9-
OAUVE
OZT
P-8
P-9
P2P
PC.
Q38
R2-
RIG
ROL
RPZ
SAB
SCU
SDF
SDG
SDP
SEN
SES
SEW
SPCBC
SPT
SSA
SSZ
T5K
TN5
WUQ
~02
~G-
~KM
AAHBH
AAXKI
AFJKZ
AKRWK
CGR
CUY
CVF
ECM
EIF
NPM
AAYXX
CITATION
1XC
VOOES
ID FETCH-LOGICAL-c446t-bbb417ac96dce2009bd96de5016c547d199cfe5952e7f70e7568b8398232cc7d3
IEDL.DBID .~1
ISSN 0166-445X
IngestDate Tue Oct 15 15:27:23 EDT 2024
Thu Sep 26 15:52:26 EDT 2024
Sat Sep 28 08:50:26 EDT 2024
Fri Feb 23 02:31:16 EST 2024
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Keywords LOEC
Micropollutants
Glycogen
EQS
SOB
dm
PFOA
AA-EQS
LOQ
hsp70
PAC
Histopathology
WWTP
PFOS
Language English
License This is an open access article under the CC BY-NC-ND license.
Copyright © 2017. Published by Elsevier B.V.
Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c446t-bbb417ac96dce2009bd96de5016c547d199cfe5952e7f70e7568b8398232cc7d3
ORCID 0000-0003-3459-6773
0000-0003-4454-3034
OpenAccessLink https://www.sciencedirect.com/science/article/pii/S0166445X17302655
PMID 28965022
PageCount 14
ParticipantIDs hal_primary_oai_HAL_hal_02047744v1
crossref_primary_10_1016_j_aquatox_2017_09_017
pubmed_primary_28965022
elsevier_sciencedirect_doi_10_1016_j_aquatox_2017_09_017
PublicationCentury 2000
PublicationDate 2017-11-01
PublicationDateYYYYMMDD 2017-11-01
PublicationDate_xml – month: 11
  year: 2017
  text: 2017-11-01
  day: 01
PublicationDecade 2010
PublicationPlace Netherlands
PublicationPlace_xml – name: Netherlands
PublicationTitle Aquatic toxicology
PublicationTitleAlternate Aquat Toxicol
PublicationYear 2017
Publisher Elsevier B.V
Elsevier
Publisher_xml – name: Elsevier B.V
– name: Elsevier
References Parrou, François (bib0285) 1997; 248
Yang, Cao, Fu (bib0455) 2015; 185
Evans (bib0105) 1987; 71
Buthiyappan, Aziz, Raman, Daud, Ashri (bib0045) 2016; 32
Triebskorn, Thellmann, Vogel, Wurm (bib0415) 2014; 7
Ezenwa, Archie, Craft, Hawley, Martin, Moore, White (bib0110) 2016; 283
He, Dai, Li, Chen (bib0150) 2015; 174
Thellmann, Greiner-Perth, Jacob, Knoll, Schäfer (bib0370) 2017; 3
Giari, Guerranti, Perra, Lanzoni, Fano, Castaldelli (bib0135) 2015; 118
Mhadhbi, Rial, Perez, Beiras (bib0245) 2012; 14
Rodriguez-Cea, Ayllon, Garcia-Vazquez (bib0315) 2003; 56
Vogel H.-J., Baur S., Triebskorn R., Rößler A., Metzger S., 2014, Die Kläranlage Albstadt-Ebingen: 20 Jahre Pulveraktivkohleeinsatz im Vollstrom. Abwassertechnische Besonderheiten und Effizienz für die Elimination von Spurenstoffen. KA Korrespondenz Abwasser, Abfall, 61.
Schwarzenbach, Escher, Fenner, Hofstetter, Johnson, von Gunten, Wehrli (bib0355) 2006; 313
Curt, Aguado, Sánchez, Bigeriego, Fernández (bib0065) 2004; 151
Köhler (bib0185) 1990; 16
Ecotox Centre(2017). Proposals for acute and chronic quality criteria. http://www.
Lim, Park, Yoo, Park, Kim, Jang, Cho, Yoo, Jung, Park (bib0215) 2005; 11
Holm (bib0165) 1979
Hung, Conte, Hallen (bib0170) 1993; 112
Camargo, Martinez (bib0050) 2007; 5
Margot, Rossi, Barry, Holliger (bib0235) 2015; 2
Morcillo, Romero, Meseguer, Esteban Á, Cuesta (bib0260) 2016; 23
Triebskorn, Adam, Casper, Honnen, Pawert, Schramm, Schwaiger, Köhler (bib0390) 2002; 11
Arslan, Ullah, Müller, Shahid, Afzal (bib0005) 2017
Eckwert, Alberti, Köhler (bib0090) 1997; 6
Tissiéres, Mitchell, Tracy (bib0380) 1974; 84
Gernhöfer, Pawert, Schramm, Müller, Triebskorn (bib0130) 2001; 8
LAWA (2003). Leitbildorientierte physikalisch-chemische Gewässerbewertung. Referenzbedingungen und Qualitätsziele. Umweltforschungsplan des Bundes-ministeriums für Umwelt, Naturschutz und Reaktorsicherheit. Forschungsbericht 20024226, UBA-FB 000322.
Pyza, Mak, Kramarz, Laskowski (bib0300) 1997; 38
Ballesteros, Rivetti, Morillo, Bertrand, Amé, Bistoni (bib0010) 2017; 595
Buckley, Carney (bib0040) 2013; 25
Basu, Todgham, Ackerman, Bibeau, Nakano, Schulte, Iwama (bib0015) 2002; 295
Tseng, Hwang (bib0425) 2008; 148
Kumar, Sharma, Tripathi, Kumar, Dalvi, Krishna (bib0205) 2016; 31
Köhler, Bartussek, Eckwert, Farian, Gränzer, Knigge, Kunz (bib0180) 2001; 8
San-Segundo, Guimarães, Torija, Beltrán, Guilhermino, Pablos (bib0330) 2016; 127
Triebskorn, Amler, Blaha, Gallert, Giebner, Güde, Henneberg, Hess, Hetzenauer, Jedele, Jung, Kneipp, Köhler, Krais, Kuch, Lange, Löffler, Maier, Metzger, Müller, Oehlmann, Osterauer, Peschke, Raizner, Rey, Rault, Richter, Sacher, Scheurer, Schneider-Rapp, Seifan, Spieth, Vogel, Weyhmüller, Winter, Wurm (bib0410) 2013; 25
Miyai, Sanches, Pinho-Neto, Barreto (bib0255) 2016; 165
Nascimento, Souza, Martinez (bib0270) 2012; 155
Volk, Liersch, Schmidt (bib0440) 2009; 26
Schwaiger, Wanke, Adam, Pawert, Honnen, Triebskorn (bib0345) 1997; 6
Koca, Koca (bib0195) 2016; 227
Kumar, Thirunavukkarasu, Subburaj, Thiagarajan (bib0200) 2015
Sørensen, Kristensen, Loeschcke (bib0325) 2003; 6
Gavrilescu, Demnerová, Aamand, Agathos, Fava (bib0125) 2015; 32
Du, Shi, Liu, Yu, Zhou (bib0075) 2009; 74
Brusle, Anadon (bib0035) 1996
Schwarz, Schmieg, Scheurer, Köhler, Triebskorn (bib0350) 2017; 607–608
Hilton (bib0160) 1982; 20
Triebskorn, Casper, Heyd, Eikemper, Köhler, Schwaiger (bib0395) 2004; 68
Bradford (bib0025) 1976; 72
EU.(2013). Directive 2013/39/EU of the European Parliament and of the Council of 12 August 2013 amending Directives 2000/60/EC and 2008/105/EC as regards priority substances in the field of water policy. OJ L226, 24.8.2013.
Sousa, Macedo, Pedrosa, Becerra-Castro, Castro-Silva, Pereira, Silva, Nunes, Nunes, Manaia (bib0360) 2017; 323
Triebskorn, Casper, Scheil, Schwaiger (bib0400) 2007; 387
European Commission(2012). Proposal for a Directive of the European parliament and of the council amending Directives 2000/60/EC and 2008/105/EC as regards priority substances in the field of water policy.
Ruhl, Altmann, Zietzschmann, Meinel, Sperlich, Jekel (bib0320) 2014; 225
Näslund, Fick, Asker, Ekman, Larsson, Norrgren (bib0265) 2017; 189
Thellmann, Köhler, Rößler, Scheurer, Schwarz, Vogel, Triebskorn (bib0365) 2015; 22
Maier, Blaha, Giesy, Henneberg, Köhler, Kuch, Osterauer, Peschke, Richter, Scheurer, Triebskorn (bib0225) 2015; 72
Maier, Benisek, Blaha, Dondero, Giesy, Köhler, Richter, Scheurer, Triebskorn (bib0230) 2016; 132
Xia, Cao, Peng, Fu, Fu (bib0450) 2014; 34
Meinel, Zietzschmann, Ruhl, Sperlich, Jekel (bib0240) 2016; 91
Thinh, Rasid, Deris, Shazili, De Boeck, Wong (bib0375) 2016; 71
Chen, Yu, Liu (bib0055) 2001; 40
Duffy, Scofield, Rodgers, Patton, Bowyer (bib0080) 1999; 124
Falås, Wick, Castronovo, Habermacher, Ternes, Joss (bib0115) 2016; 95
Birzle (bib0020) 2015
Knopp, Prasse, Ternes, Cornel (bib0190) 2016; 100
Qiang, Cheng, Yi, Rotchell, Zhu, Zhou (bib0305) 2016; 25
Olson (bib0275) 2002; 293
Hagenaars, Stinckens, Vergauwen, Bervoets, Knapen (bib0145) 2014; 157
last accessed July 2nd, 2017.
Schmidt-Posthaus, Bernet, Wahli, Burkhardt-Holm (bib0340) 2001; 44
ICPR. (2009). Sediment management plan Rhine. Koblenz, Germany.
Triebskorn, Köhler, Honnen, Schramm, Adams, Müller (bib0385) 1997; 6
Haap, Triebskorn, Köhler (bib0140) 2008; 73
Pan, Yuan, Zhang, Wang, Chen, Lu, Yang, Li, Zhao, Xu (bib0280) 2016; 31
Vincze, Scheil, Kuch, Köhler, Triebskorn (bib0430) 2015
Triebskorn, R. (2017). Weitergehende Abwasserreinigung: ein wirksames und bezahlbares Instrument zur Verminderung von Spurenstoffen und Keimen im Wasserkreislauf: gemeinsamer Schlussbericht der vom Bundesministerium für Bildung und Forschung sowie vom Ministerium für Umwelt, Klima und Energiewirtschaft Baden-Württemberg geförderten Projekte SchussenAktiv, SchussenAktivplus und SchussenAktivplus+. Universitätsbibliothek Tübingen, Tübingen, Germany.
Contardo-Jara, Lorenz, Pflugmacher, Nützmann, Kloas, Wiegan (bib0060) 2011; 105
Midwood, Larsen, Cooke (bib0250) 2016; 219
Sanders, Nguyen, Martin, Howe, Coventry (bib0335) 1995; 112
Henneberg, Bender, Blaha, Giebner, Kuch, Köhler, Maier, Oehlmann, Richter, Scheurer, Schulte-Oehlmann, Sieratowicz, Ziebart, Triebskorn (bib0155) 2014; 9
Braunbeck (bib0030) 1998; vol. 86
Delaney, Klesius (bib0070) 2004; 236
Triebskorn, Telcean, Casper, Farkas, Sandu, Stan, Colărescu, Dori, Dori, Köhler (bib0405) 2008; 141
R Core Team(2015). R: A language and environment for statistical computing.
Last accessed: July, 2nd 2017.
Lima, Sayanda, Soares, Wrona, Monaghan (bib0220) 2016; 74
Pickering, Pottinger, Carragher (bib0295) 1989; 34
Wiseman, Vijayan (bib0445) 2011; 154
Peschke, Burmester, Hermann, Köhler, Reitter, Scheurer, Wurm, Triebskorn (bib0290) 2016; 157
Galus, Kirischian, Higgins, Purdy, Chow, Rangaranjan, Li, Metcalfe, Wilson (bib0120) 2013; 132–133
Köhler (10.1016/j.aquatox.2017.09.017_bib0185) 1990; 16
Buthiyappan (10.1016/j.aquatox.2017.09.017_bib0045) 2016; 32
Schwarzenbach (10.1016/j.aquatox.2017.09.017_bib0355) 2006; 313
Basu (10.1016/j.aquatox.2017.09.017_bib0015) 2002; 295
Lim (10.1016/j.aquatox.2017.09.017_bib0215) 2005; 11
Chen (10.1016/j.aquatox.2017.09.017_bib0055) 2001; 40
Schwarz (10.1016/j.aquatox.2017.09.017_bib0350) 2017; 607–608
10.1016/j.aquatox.2017.09.017_bib0420
Midwood (10.1016/j.aquatox.2017.09.017_bib0250) 2016; 219
Tseng (10.1016/j.aquatox.2017.09.017_bib0425) 2008; 148
Maier (10.1016/j.aquatox.2017.09.017_bib0230) 2016; 132
Thellmann (10.1016/j.aquatox.2017.09.017_bib0370) 2017; 3
Delaney (10.1016/j.aquatox.2017.09.017_bib0070) 2004; 236
10.1016/j.aquatox.2017.09.017_bib0100
Henneberg (10.1016/j.aquatox.2017.09.017_bib0155) 2014; 9
Lima (10.1016/j.aquatox.2017.09.017_bib0220) 2016; 74
Morcillo (10.1016/j.aquatox.2017.09.017_bib0260) 2016; 23
Olson (10.1016/j.aquatox.2017.09.017_bib0275) 2002; 293
Parrou (10.1016/j.aquatox.2017.09.017_bib0285) 1997; 248
Birzle (10.1016/j.aquatox.2017.09.017_bib0020) 2015
Kumar (10.1016/j.aquatox.2017.09.017_bib0205) 2016; 31
He (10.1016/j.aquatox.2017.09.017_bib0150) 2015; 174
Peschke (10.1016/j.aquatox.2017.09.017_bib0290) 2016; 157
Triebskorn (10.1016/j.aquatox.2017.09.017_bib0400) 2007; 387
Meinel (10.1016/j.aquatox.2017.09.017_bib0240) 2016; 91
Köhler (10.1016/j.aquatox.2017.09.017_bib0180) 2001; 8
Triebskorn (10.1016/j.aquatox.2017.09.017_bib0395) 2004; 68
Schmidt-Posthaus (10.1016/j.aquatox.2017.09.017_bib0340) 2001; 44
Yang (10.1016/j.aquatox.2017.09.017_bib0455) 2015; 185
Arslan (10.1016/j.aquatox.2017.09.017_bib0005) 2017
Thinh (10.1016/j.aquatox.2017.09.017_bib0375) 2016; 71
San-Segundo (10.1016/j.aquatox.2017.09.017_bib0330) 2016; 127
Margot (10.1016/j.aquatox.2017.09.017_bib0235) 2015; 2
Qiang (10.1016/j.aquatox.2017.09.017_bib0305) 2016; 25
Näslund (10.1016/j.aquatox.2017.09.017_bib0265) 2017; 189
10.1016/j.aquatox.2017.09.017_bib0310
Tissiéres (10.1016/j.aquatox.2017.09.017_bib0380) 1974; 84
Vincze (10.1016/j.aquatox.2017.09.017_bib0430) 2015
Gavrilescu (10.1016/j.aquatox.2017.09.017_bib0125) 2015; 32
Xia (10.1016/j.aquatox.2017.09.017_bib0450) 2014; 34
Nascimento (10.1016/j.aquatox.2017.09.017_bib0270) 2012; 155
10.1016/j.aquatox.2017.09.017_bib0435
Duffy (10.1016/j.aquatox.2017.09.017_bib0080) 1999; 124
Triebskorn (10.1016/j.aquatox.2017.09.017_bib0405) 2008; 141
Triebskorn (10.1016/j.aquatox.2017.09.017_bib0415) 2014; 7
Maier (10.1016/j.aquatox.2017.09.017_bib0225) 2015; 72
Koca (10.1016/j.aquatox.2017.09.017_bib0195) 2016; 227
Volk (10.1016/j.aquatox.2017.09.017_bib0440) 2009; 26
Giari (10.1016/j.aquatox.2017.09.017_bib0135) 2015; 118
10.1016/j.aquatox.2017.09.017_bib0085
Gernhöfer (10.1016/j.aquatox.2017.09.017_bib0130) 2001; 8
Kumar (10.1016/j.aquatox.2017.09.017_bib0200) 2015
Ruhl (10.1016/j.aquatox.2017.09.017_bib0320) 2014; 225
Camargo (10.1016/j.aquatox.2017.09.017_bib0050) 2007; 5
Miyai (10.1016/j.aquatox.2017.09.017_bib0255) 2016; 165
Buckley (10.1016/j.aquatox.2017.09.017_bib0040) 2013; 25
Mhadhbi (10.1016/j.aquatox.2017.09.017_bib0245) 2012; 14
Pyza (10.1016/j.aquatox.2017.09.017_bib0300) 1997; 38
Sousa (10.1016/j.aquatox.2017.09.017_bib0360) 2017; 323
Haap (10.1016/j.aquatox.2017.09.017_bib0140) 2008; 73
Sanders (10.1016/j.aquatox.2017.09.017_bib0335) 1995; 112
Triebskorn (10.1016/j.aquatox.2017.09.017_bib0410) 2013; 25
Hilton (10.1016/j.aquatox.2017.09.017_bib0160) 1982; 20
Ballesteros (10.1016/j.aquatox.2017.09.017_bib0010) 2017; 595
Triebskorn (10.1016/j.aquatox.2017.09.017_bib0390) 2002; 11
Triebskorn (10.1016/j.aquatox.2017.09.017_bib0385) 1997; 6
Falås (10.1016/j.aquatox.2017.09.017_bib0115) 2016; 95
Knopp (10.1016/j.aquatox.2017.09.017_bib0190) 2016; 100
Sørensen (10.1016/j.aquatox.2017.09.017_bib0325) 2003; 6
Hung (10.1016/j.aquatox.2017.09.017_bib0170) 1993; 112
10.1016/j.aquatox.2017.09.017_bib0095
Eckwert (10.1016/j.aquatox.2017.09.017_bib0090) 1997; 6
Rodriguez-Cea (10.1016/j.aquatox.2017.09.017_bib0315) 2003; 56
Contardo-Jara (10.1016/j.aquatox.2017.09.017_bib0060) 2011; 105
10.1016/j.aquatox.2017.09.017_bib0175
Braunbeck (10.1016/j.aquatox.2017.09.017_bib0030) 1998; vol. 86
10.1016/j.aquatox.2017.09.017_bib0210
Galus (10.1016/j.aquatox.2017.09.017_bib0120) 2013; 132–133
Thellmann (10.1016/j.aquatox.2017.09.017_bib0365) 2015; 22
Curt (10.1016/j.aquatox.2017.09.017_bib0065) 2004; 151
Evans (10.1016/j.aquatox.2017.09.017_bib0105) 1987; 71
Hagenaars (10.1016/j.aquatox.2017.09.017_bib0145) 2014; 157
Ezenwa (10.1016/j.aquatox.2017.09.017_bib0110) 2016; 283
Brusle (10.1016/j.aquatox.2017.09.017_bib0035) 1996
Pickering (10.1016/j.aquatox.2017.09.017_bib0295) 1989; 34
Schwaiger (10.1016/j.aquatox.2017.09.017_bib0345) 1997; 6
Wiseman (10.1016/j.aquatox.2017.09.017_bib0445) 2011; 154
Holm (10.1016/j.aquatox.2017.09.017_bib0165) 1979
Pan (10.1016/j.aquatox.2017.09.017_bib0280) 2016; 31
Bradford (10.1016/j.aquatox.2017.09.017_bib0025) 1976; 72
Du (10.1016/j.aquatox.2017.09.017_bib0075) 2009; 74
References_xml – volume: 595
  start-page: 711
  year: 2017
  end-page: 722
  ident: bib0010
  article-title: Multi-biomarker responses in fish (
  publication-title: Sci. Total Environ.
  contributor:
    fullname: Bistoni
– volume: 26
  start-page: 580
  year: 2009
  end-page: 588
  ident: bib0440
  article-title: Towards the implementation of the European water framework directive?
  publication-title: Land Use Policy
  contributor:
    fullname: Schmidt
– volume: 20
  start-page: 69
  year: 1982
  end-page: 78
  ident: bib0160
  article-title: The effect of pre-fasting diet and water temperature on liver glycogen and liver weight in rainbow trout,
  publication-title: J. Fish Biol.
  contributor:
    fullname: Hilton
– volume: 6
  start-page: 75
  year: 1997
  end-page: 86
  ident: bib0345
  article-title: The use of histopathological indicators to evaluate contaminant-related stress in fish
  publication-title: J. Aquat. Ecosyst. Stress Recov.
  contributor:
    fullname: Triebskorn
– start-page: 65
  year: 2017
  end-page: 99
  ident: bib0005
  article-title: Organic micropollutants in the environment: ecotoxicity potential and methods for remediation
  publication-title: Enhancing Cleanup of Environmental Pollutants: Volume 1: Biological Approaches
  contributor:
    fullname: Afzal
– volume: 9
  start-page: e98307
  year: 2014
  ident: bib0155
  article-title: Are in vitro methods for the detection of endocrine potentials in the aquatic environment predictive for in vivo effects? Outcomes of the projects SchussenAktiv and SchussenAktivplus in the Lake Constance area, Germany
  publication-title: PLoS One
  contributor:
    fullname: Triebskorn
– volume: 25
  start-page: 118
  year: 2013
  end-page: 126
  ident: bib0040
  article-title: The potential to reduce the risk of diffuse pollution from agriculture while improving economic performance at farm level
  publication-title: Environ. Sci. Policy
  contributor:
    fullname: Carney
– volume: 2
  start-page: 457
  year: 2015
  end-page: 487
  ident: bib0235
  article-title: A review of the fate of micropollutants in wastewater treatment plants
  publication-title: Wiley Interdiscip. Rev.: Water
  contributor:
    fullname: Holliger
– volume: 3
  year: 2017
  ident: bib0370
  article-title: Does waste water treatment plant upgrading with powdered activated carbon result in reduced water and sediment toxicity of the receiving stream
  publication-title: Int. J. Water Wastewater Treat.
  contributor:
    fullname: Schäfer
– volume: 11
  start-page: 2072
  year: 2005
  end-page: 2079
  ident: bib0215
  article-title: Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic nodules
  publication-title: World J. Gastroenterol.
  contributor:
    fullname: Park
– volume: 44
  start-page: 161
  year: 2001
  end-page: 170
  ident: bib0340
  article-title: Morphological organ alterations and infectious diseases in brown trout
  publication-title: Dis. Aquat. Organ.
  contributor:
    fullname: Burkhardt-Holm
– volume: 32
  start-page: 1
  year: 2016
  end-page: 47
  ident: bib0045
  article-title: Recent advances and prospects of catalytic advanced oxidation process in treating textile effluents
  publication-title: Rev. Chem. Eng.
  contributor:
    fullname: Ashri
– volume: 38
  start-page: 244
  year: 1997
  end-page: 251
  ident: bib0300
  article-title: Heat shock proteins (HSP70) as biomarkers in ecotoxicological studies
  publication-title: Ecotoxicol. Environ. Saf.
  contributor:
    fullname: Laskowski
– volume: 295
  start-page: 173
  year: 2002
  end-page: 183
  ident: bib0015
  article-title: Heat shock protein genes and their functional significance in fish
  publication-title: Gene
  contributor:
    fullname: Iwama
– volume: 11
  start-page: 451
  year: 2002
  end-page: 465
  ident: bib0390
  article-title: Biomarkers as diagnostic tools for evaluating effects of unknown past water quality conditions on stream organisms
  publication-title: Ecotoxicology
  contributor:
    fullname: Köhler
– volume: 154
  start-page: 254
  year: 2011
  end-page: 260
  ident: bib0445
  article-title: Aroclor 1254 disrupts liver glycogen metabolism and enhances acute stressor-mediated glycogenolysis in rainbow trout
  publication-title: Comp. Biochem. Physiol. − Part C: Toxicol. Pharmacol.
  contributor:
    fullname: Vijayan
– volume: 313
  start-page: 1072
  year: 2006
  end-page: 1077
  ident: bib0355
  article-title: The challenge of micropollutants in aquatic systems
  publication-title: Science
  contributor:
    fullname: Wehrli
– volume: 132
  start-page: 47
  year: 2016
  end-page: 58
  ident: bib0230
  article-title: Reduction of dioxin-like toxicity in effluents by additional wastewater treatment and related effects in fish
  publication-title: Ecotoxicol. Environ. Saf.
  contributor:
    fullname: Triebskorn
– volume: 56
  start-page: 442
  year: 2003
  end-page: 448
  ident: bib0315
  article-title: Micronucleus test in freshwater fish species: an evaluation of its sensitivity for application in field surveys
  publication-title: Ecotoxicol. Environ. Saf.
  contributor:
    fullname: Garcia-Vazquez
– volume: 32
  start-page: 147
  year: 2015
  end-page: 156
  ident: bib0125
  article-title: Emerging pollutants in the environment: present and future challenges in biomonitoring, ecological risks and bioremediation
  publication-title: New Biotechnol.
  contributor:
    fullname: Fava
– volume: 323
  start-page: 434
  year: 2017
  end-page: 441
  ident: bib0360
  article-title: Ozonation and UV 254
  publication-title: J. Hazard. Mater.
  contributor:
    fullname: Manaia
– volume: vol. 86
  start-page: 61
  year: 1998
  end-page: 140
  ident: bib0030
  article-title: Cytological alterations in fish hepatocytes following in vivo and in vitro sublethal exposure to xenobiotics—structural biomarkers of environmental contamination
  publication-title: Fish Ecotoxicology
  contributor:
    fullname: Braunbeck
– volume: 6
  start-page: 57
  year: 1997
  end-page: 73
  ident: bib0385
  article-title: Induction of heat shock proteins, changes in liver ultrastructure, and alterations of fish behavior: are these biomarkers related and are they useful to reflect the state of pollution in the field?
  publication-title: J. Aquat. Ecosyst. Stress Recov.
  contributor:
    fullname: Müller
– volume: 74
  start-page: 452
  year: 2016
  end-page: 464
  ident: bib0220
  article-title: Integrating taxonomic and trait analyses to assess the impact of damming on fish communities in a northern cold region river
  publication-title: Can. J. Fish. Aquat.Sci.
  contributor:
    fullname: Monaghan
– volume: 8
  start-page: 241
  year: 2001
  end-page: 260
  ident: bib0130
  article-title: Ultrastructural biomarkers as tools to characterize the health status of fish in contaminated streams
  publication-title: J. Aquat. Ecosyst. Stress Recov.
  contributor:
    fullname: Triebskorn
– volume: 23
  start-page: 12312
  year: 2016
  end-page: 12322
  ident: bib0260
  article-title: Cytotoxicity and alterations at transcriptional level caused by metals on fish erythrocytes in vitro
  publication-title: Environ. Sci. Pollut. Res.
  contributor:
    fullname: Cuesta
– volume: 155
  start-page: 456
  year: 2012
  end-page: 461
  ident: bib0270
  article-title: Copper and the herbicide atrazine impair the stress response of the freshwater fish Prochilodus lineatus
  publication-title: Comp. Biochem. Physiol.—Part C: Toxicol. Pharmacol.
  contributor:
    fullname: Martinez
– volume: 16
  start-page: 271
  year: 1990
  end-page: 293
  ident: bib0185
  article-title: Identification of contaminant-induced cellular and subcellular lesions in the liver of flounder (
  publication-title: Aquat. Toxicol.
  contributor:
    fullname: Köhler
– volume: 84
  start-page: 389
  year: 1974
  end-page: 398
  ident: bib0380
  article-title: Protein synthesis in salivary glands of
  publication-title: J. Mol. Biol.
  contributor:
    fullname: Tracy
– volume: 227
  start-page: 1
  year: 2016
  ident: bib0195
  article-title: Genotoxic and histopathological effects of olive-mill wastewater on Lepomis gibbosus
  publication-title: Water Air Soil Pollut.
  contributor:
    fullname: Koca
– start-page: 95
  year: 2015
  end-page: 100
  ident: bib0200
  article-title: Concept of stress and its mitigation in aquaculture
  publication-title: Advances in Marine and Brackishwater Aquaculture
  contributor:
    fullname: Thiagarajan
– volume: 112
  start-page: 335
  year: 1995
  end-page: 343
  ident: bib0335
  article-title: Induction and subcellular localization of two major stress proteins in response to copper in the fathead minnow
  publication-title: Comp. Biochem. Physiol. Part C: Pharmacol. Toxicol. Endocrinol.
  contributor:
    fullname: Coventry
– start-page: 77
  year: 1996
  end-page: 93
  ident: bib0035
  article-title: The structure and function of fish liver
  publication-title: Fish Morphol.
  contributor:
    fullname: Anadon
– volume: 7
  year: 2014
  ident: bib0415
  article-title: Die Kläranlage Albstadt-Ebingen: Aktivkohlefilterung im Vollstrom seit 1992-Ein langfristiger Erfolg für die Fischgesundheit und die Gewässerökologie
  publication-title: Korrespondenz Wasserwirtschaft.
  contributor:
    fullname: Wurm
– volume: 34
  start-page: 284
  year: 2014
  end-page: 289
  ident: bib0450
  article-title: The use of spontaneous behavior, swimming performances and metabolic rate to evaluate toxicity of PFOS on topmouth gudgeon
  publication-title: Acta Ecol. Sin.
  contributor:
    fullname: Fu
– volume: 72
  start-page: 248
  year: 1976
  end-page: 254
  ident: bib0025
  article-title: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
  publication-title: Anal. Biochem.
  contributor:
    fullname: Bradford
– volume: 189
  start-page: 87
  year: 2017
  end-page: 96
  ident: bib0265
  article-title: Diclofenac affects kidney histology in the three-spined stickleback (
  publication-title: Aquat. Toxicol.
  contributor:
    fullname: Norrgren
– volume: 34
  start-page: 757
  year: 1989
  end-page: 768
  ident: bib0295
  article-title: Differences in the sensitivity of brown trout,
  publication-title: J. Fish Biol.
  contributor:
    fullname: Carragher
– volume: 127
  start-page: 51
  year: 2016
  end-page: 60
  ident: bib0330
  article-title: Alterations in gene expression levels provide early indicators of chemical stress during
  publication-title: Ecotoxicol. Environ. Saf.
  contributor:
    fullname: Pablos
– volume: 72
  start-page: 127
  year: 2015
  end-page: 144
  ident: bib0225
  article-title: Biological plausibility as a tool to associate analytical data for micropollutants and effect potentials in wastewater, surface water, and sediments with effects in fishes
  publication-title: Water Res.
  contributor:
    fullname: Triebskorn
– volume: 74
  start-page: 723
  year: 2009
  end-page: 729
  ident: bib0075
  article-title: Chronic effects of water-borne PFOS exposure on growth, survival and hepatotoxicity in zebrafish: a partial life-cycle test
  publication-title: Chemosphere
  contributor:
    fullname: Zhou
– volume: 112
  start-page: 349
  year: 1993
  end-page: 361
  ident: bib0170
  article-title: Effects of feeding rates on growth, body composition and nutrient metabolism in striped bass (
  publication-title: Aquaculture
  contributor:
    fullname: Hallen
– volume: 174
  start-page: 180
  year: 2015
  end-page: 187
  ident: bib0150
  article-title: Occurrence and assessment of perfluorinated compounds in fish from the Danjiangkou reservoir and Hanjiang river in China
  publication-title: Food Chem.
  contributor:
    fullname: Chen
– volume: 132–133
  start-page: 200
  year: 2013
  end-page: 211
  ident: bib0120
  article-title: Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish
  publication-title: Aquat. Toxicol.
  contributor:
    fullname: Wilson
– volume: 105
  start-page: 428
  year: 2011
  end-page: 437
  ident: bib0060
  article-title: Exposure to human pharmaceuticals carbamazepine, ibuprofen and bezafibrate causes molecular effects in
  publication-title: Aquat. Toxicol.
  contributor:
    fullname: Wiegan
– volume: 157
  start-page: 370
  year: 2016
  end-page: 379
  ident: bib0290
  article-title: Reaktionen von Flohkrebsen und Makrozoobenthos auf die Nachröstung einer Klüranlage mit einer Pulveraktivkohlestufe
  publication-title: gwf − Wasser/Abwasser
  contributor:
    fullname: Triebskorn
– volume: 31
  start-page: 110
  year: 2016
  end-page: 119
  ident: bib0280
  article-title: A review of ecological restoration techniques in fluvial rivers, International
  publication-title: J. Sediment. Res.
  contributor:
    fullname: Xu
– volume: 91
  start-page: 97
  year: 2016
  end-page: 103
  ident: bib0240
  article-title: The benefits of powdered activated carbon recirculation for micropollutant removal in advanced wastewater treatment
  publication-title: Water Res.
  contributor:
    fullname: Jekel
– volume: 165
  start-page: 22
  year: 2016
  end-page: 27
  ident: bib0255
  article-title: Effects of predator odour on antipredator responses of Nile tilapia
  publication-title: Physiol. Behav.
  contributor:
    fullname: Barreto
– start-page: 1
  year: 2015
  end-page: 18
  ident: bib0430
  article-title: Impact of wastewater on fish health: a case study at the Neckar River (Southern Germany) using biomarkers in caged brown trout as assessment tools
  publication-title: Environ. Sci. Pollut. Res.
  contributor:
    fullname: Triebskorn
– volume: 8
  start-page: 261
  year: 2001
  end-page: 279
  ident: bib0180
  article-title: The hepatic stress protein (hsp70) response to interacting abiotic parameters in fish exposed to various levels of pollution
  publication-title: J. Aquat. Ecosyst. Stress Recov.
  contributor:
    fullname: Kunz
– volume: 68
  start-page: 151
  year: 2004
  end-page: 166
  ident: bib0395
  article-title: Toxic effects of the non-steroidal anti-inflammatory drug diclofenac: part II. Cytological effects in liver, kidney, gills and intestine of rainbow trout (
  publication-title: Aquat. Toxicol.
  contributor:
    fullname: Schwaiger
– volume: 31
  start-page: 106
  year: 2016
  end-page: 115
  ident: bib0205
  article-title: Cellular metabolic, stress, and histological response on exposure to acute toxicity of endosulfan in Tilapia (
  publication-title: Environ. Toxicol.
  contributor:
    fullname: Krishna
– volume: 25
  start-page: 1
  year: 2013
  end-page: 9
  ident: bib0410
  article-title: SchussenAktivplus: reduction of micropollutants and of potentially pathogenic bacteria for further water quality improvement of the river Schussen, a tributary of Lake Constance, Germany
  publication-title: Environ. Sci. Eur.
  contributor:
    fullname: Wurm
– volume: 185
  start-page: 16
  year: 2015
  end-page: 23
  ident: bib0455
  article-title: Variations in temperature acclimation effects on glycogen storage, hypoxia tolerance and swimming performance with seasonal acclimatization in juvenile Chinese crucian carp
  publication-title: Comp. Biochem. Physiol. Part A: Mol. Integr. Physiol.
  contributor:
    fullname: Fu
– volume: 157
  start-page: 225
  year: 2014
  end-page: 235
  ident: bib0145
  article-title: PFOS affects posterior swim bladder chamber inflation and swimming performance of zebrafish larvae
  publication-title: Aquat. Toxicol.
  contributor:
    fullname: Knapen
– volume: 71
  start-page: 47
  year: 1987
  end-page: 58
  ident: bib0105
  article-title: The fish gill: site of action and model for toxic effects of environmental pollutants
  publication-title: Environ. Health Perspect.
  contributor:
    fullname: Evans
– volume: 6
  start-page: 1025
  year: 2003
  end-page: 1037
  ident: bib0325
  article-title: The evolutionary and ecological role of heat shock proteins
  publication-title: Ecol. Lett.
  contributor:
    fullname: Loeschcke
– volume: 124
  start-page: 181
  year: 1999
  end-page: 186
  ident: bib0080
  article-title: Comparative baseline levels of mercury, Hsp70 and Hsp60 in subsistence fish from the Yukon-Kuskokwim delta region of Alaska
  publication-title: Comp. Biochem. Physiol. Part C: Pharmacol. Toxicol. Endocrinol.
  contributor:
    fullname: Bowyer
– year: 2015
  ident: bib0020
  article-title: Etablierung und Validierung quantitativ-morphologischer Parameter bei Regenbogenforellen im Rahmen ökotoxikologischer Fragestellungen. (Doctoral Thesis)
  contributor:
    fullname: Birzle
– volume: 5
  start-page: 327
  year: 2007
  end-page: 336
  ident: bib0050
  article-title: Histopathology of gills, kidney and liver of a Neotropical fish caged in an urban stream
  publication-title: Neotrop. Ichthyol.
  contributor:
    fullname: Martinez
– volume: 387
  start-page: 1405
  year: 2007
  end-page: 1416
  ident: bib0400
  article-title: Ultrastructural effects of pharmaceuticals (carbamazepine, clofibric acid, metoprolol, diclofenac) in rainbow trout (
  publication-title: Anal. Bioanal. Chem.
  contributor:
    fullname: Schwaiger
– volume: 283
  start-page: 1828
  year: 2016
  ident: bib0110
  article-title: Host behaviour–parasite feedback: an essential link between animal behaviour and disease ecology
  publication-title: Proc. R. Soc. B: Biol. Sci.
  contributor:
    fullname: White
– volume: 148
  start-page: 419
  year: 2008
  end-page: 429
  ident: bib0425
  article-title: Some insights into energy metabolism for osmoregulation in fish
  publication-title: Comp. Biochem. Physiol.—Part C: Toxicol. Pharmacol.
  contributor:
    fullname: Hwang
– volume: 219
  start-page: 3712
  year: 2016
  end-page: 3718
  ident: bib0250
  article-title: Stress and food deprivation: linking physiological state to migration success in a teleost fish
  publication-title: J. Exp. Biol.
  contributor:
    fullname: Cooke
– volume: 71
  start-page: 530
  year: 2016
  end-page: 540
  ident: bib0375
  article-title: Putative roles for metallothionein and HSP70 genes in relation with heavy metal accumulation and parasitic cymothoid in the fish Nemipterus furcosus
  publication-title: Arch. Environ. Contam. Toxicol.
  contributor:
    fullname: Wong
– volume: 6
  start-page: 249
  year: 1997
  end-page: 262
  ident: bib0090
  article-title: The induction of stress proteins (hsp) in
  publication-title: Ecotoxicology
  contributor:
    fullname: Köhler
– volume: 40
  start-page: 363
  year: 2001
  end-page: 370
  ident: bib0055
  article-title: Use of Japanese medaka (
  publication-title: Arch. Environ. Contam. Toxicol.
  contributor:
    fullname: Liu
– volume: 73
  start-page: 353
  year: 2008
  end-page: 359
  ident: bib0140
  article-title: Acute effects of diclofenac and DMSO to
  publication-title: Chemosphere
  contributor:
    fullname: Köhler
– volume: 293
  start-page: 320
  year: 2002
  end-page: 335
  ident: bib0275
  article-title: Gill circulation: regulation of perfusion distribution and metabolism of regulatory molecules
  publication-title: J. Exp. Zool.
  contributor:
    fullname: Olson
– volume: 118
  start-page: 117
  year: 2015
  end-page: 123
  ident: bib0135
  article-title: Occurrence of perfluorooctanesulfonate and perfluorooctanoic acid and histopathology in eels from north Italian waters
  publication-title: Chemosphere
  contributor:
    fullname: Castaldelli
– volume: 14
  start-page: 1375
  year: 2012
  end-page: 1382
  ident: bib0245
  article-title: Ecological risk assessment of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in marine environment using
  publication-title: J. Environ. Monit.
  contributor:
    fullname: Beiras
– volume: 225
  start-page: 1877
  year: 2014
  ident: bib0320
  article-title: Integrating micro-pollutant removal by powdered activated carbon into deep bed filtration
  publication-title: Water Air Soil Pollut.
  contributor:
    fullname: Jekel
– volume: 22
  start-page: 16405
  year: 2015
  end-page: 16416
  ident: bib0365
  article-title: Fish embryo tests with
  publication-title: Environ. Sci. Pollut. Res.
  contributor:
    fullname: Triebskorn
– start-page: 65
  year: 1979
  end-page: 70
  ident: bib0165
  article-title: A simple sequentially rejective multiple test procedure
  publication-title: Scand. J. Stat.
  contributor:
    fullname: Holm
– volume: 248
  start-page: 186
  year: 1997
  end-page: 188
  ident: bib0285
  article-title: A simplified procedure for a rapid and reliable assay of both glycogen and trehalose in whole yeast cells
  publication-title: Anal. Biochem.
  contributor:
    fullname: François
– volume: 151
  start-page: 135
  year: 2004
  end-page: 142
  ident: bib0065
  article-title: Nitrogen isotope ratios of synthetic and organic sources of nitrate water contamination in spain
  publication-title: Water Air Soil Pollut.
  contributor:
    fullname: Fernández
– volume: 100
  start-page: 580
  year: 2016
  end-page: 592
  ident: bib0190
  article-title: Elimination of micropollutants and transformation products from a wastewater treatment plant effluent through pilot scale ozonation followed by various activated carbon and biological filters
  publication-title: Water Res.
  contributor:
    fullname: Cornel
– volume: 25
  start-page: 1426
  year: 2016
  end-page: 1437
  ident: bib0305
  article-title: Environmental concentration of carbamazepine accelerates fish embryonic development and disturbs larvae behavior
  publication-title: Ecotoxicology
  contributor:
    fullname: Zhou
– volume: 141
  start-page: 177
  year: 2008
  end-page: 188
  ident: bib0405
  article-title: Monitoring pollution in River Mureă, Romania, part II: Metal accumulation and histopathology in fish
  publication-title: Environ. Monit. Assess.
  contributor:
    fullname: Köhler
– volume: 95
  start-page: 240
  year: 2016
  end-page: 249
  ident: bib0115
  article-title: Tracing the limits of organic micropollutant removal in biological wastewater treatment
  publication-title: Water Res.
  contributor:
    fullname: Joss
– volume: 236
  start-page: 633
  year: 2004
  end-page: 644
  ident: bib0070
  article-title: Hypoxic conditions induce Hsp70 production in blood, brain and head kidney of juvenile nile tilapia
  publication-title: Aquaculture
  contributor:
    fullname: Klesius
– volume: 607–608
  start-page: 1026
  year: 2017
  end-page: 1036
  ident: bib0350
  article-title: Impact of the NSAID diclofenac on survival, development, behaviour and health of embryonic and juvenile stages of brown trout,
  publication-title: Sci. Total Environ.
  contributor:
    fullname: Triebskorn
– volume: 387
  start-page: 1405
  issue: 4
  year: 2007
  ident: 10.1016/j.aquatox.2017.09.017_bib0400
  article-title: Ultrastructural effects of pharmaceuticals (carbamazepine, clofibric acid, metoprolol, diclofenac) in rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio)
  publication-title: Anal. Bioanal. Chem.
  doi: 10.1007/s00216-006-1033-x
  contributor:
    fullname: Triebskorn
– volume: 72
  start-page: 127
  issue: 0
  year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0225
  article-title: Biological plausibility as a tool to associate analytical data for micropollutants and effect potentials in wastewater, surface water, and sediments with effects in fishes
  publication-title: Water Res.
  doi: 10.1016/j.watres.2014.08.050
  contributor:
    fullname: Maier
– volume: 25
  start-page: 1
  issue: 1
  year: 2013
  ident: 10.1016/j.aquatox.2017.09.017_bib0410
  article-title: SchussenAktivplus: reduction of micropollutants and of potentially pathogenic bacteria for further water quality improvement of the river Schussen, a tributary of Lake Constance, Germany
  publication-title: Environ. Sci. Eur.
  doi: 10.1186/2190-4715-25-2
  contributor:
    fullname: Triebskorn
– volume: 44
  start-page: 161
  issue: 3
  year: 2001
  ident: 10.1016/j.aquatox.2017.09.017_bib0340
  article-title: Morphological organ alterations and infectious diseases in brown trout Salmo trutta and rainbow trout Oncorhynchus mykiss exposed to polluted river water
  publication-title: Dis. Aquat. Organ.
  doi: 10.3354/dao044161
  contributor:
    fullname: Schmidt-Posthaus
– volume: 323
  start-page: 434
  year: 2017
  ident: 10.1016/j.aquatox.2017.09.017_bib0360
  article-title: Ozonation and UV 254nm radiation for the removal of microorganisms and antibiotic resistance genes from urban wastewater
  publication-title: J. Hazard. Mater.
  doi: 10.1016/j.jhazmat.2016.03.096
  contributor:
    fullname: Sousa
– ident: 10.1016/j.aquatox.2017.09.017_bib0310
– volume: 71
  start-page: 530
  issue: 4
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0375
  article-title: Putative roles for metallothionein and HSP70 genes in relation with heavy metal accumulation and parasitic cymothoid in the fish Nemipterus furcosus
  publication-title: Arch. Environ. Contam. Toxicol.
  doi: 10.1007/s00244-016-0310-8
  contributor:
    fullname: Thinh
– volume: 112
  start-page: 349
  issue: 4
  year: 1993
  ident: 10.1016/j.aquatox.2017.09.017_bib0170
  article-title: Effects of feeding rates on growth, body composition and nutrient metabolism in striped bass (Morone saxatilis) fingerlings
  publication-title: Aquaculture
  doi: 10.1016/0044-8486(93)90395-F
  contributor:
    fullname: Hung
– volume: 105
  start-page: 428
  issue: 3
  year: 2011
  ident: 10.1016/j.aquatox.2017.09.017_bib0060
  article-title: Exposure to human pharmaceuticals carbamazepine, ibuprofen and bezafibrate causes molecular effects in Dreissena polymorpha
  publication-title: Aquat. Toxicol.
  doi: 10.1016/j.aquatox.2011.07.017
  contributor:
    fullname: Contardo-Jara
– volume: 148
  start-page: 419
  issue: 4
  year: 2008
  ident: 10.1016/j.aquatox.2017.09.017_bib0425
  article-title: Some insights into energy metabolism for osmoregulation in fish
  publication-title: Comp. Biochem. Physiol.—Part C: Toxicol. Pharmacol.
  contributor:
    fullname: Tseng
– volume: 118
  start-page: 117
  issue: 0
  year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0135
  article-title: Occurrence of perfluorooctanesulfonate and perfluorooctanoic acid and histopathology in eels from north Italian waters
  publication-title: Chemosphere
  doi: 10.1016/j.chemosphere.2014.06.066
  contributor:
    fullname: Giari
– volume: 607–608
  start-page: 1026
  year: 2017
  ident: 10.1016/j.aquatox.2017.09.017_bib0350
  article-title: Impact of the NSAID diclofenac on survival, development, behaviour and health of embryonic and juvenile stages of brown trout, Salmo trutta f. fario
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2017.07.042
  contributor:
    fullname: Schwarz
– volume: 157
  start-page: 225
  year: 2014
  ident: 10.1016/j.aquatox.2017.09.017_bib0145
  article-title: PFOS affects posterior swim bladder chamber inflation and swimming performance of zebrafish larvae
  publication-title: Aquat. Toxicol.
  doi: 10.1016/j.aquatox.2014.10.017
  contributor:
    fullname: Hagenaars
– volume: 185
  start-page: 16
  issue: 0
  year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0455
  article-title: Variations in temperature acclimation effects on glycogen storage, hypoxia tolerance and swimming performance with seasonal acclimatization in juvenile Chinese crucian carp
  publication-title: Comp. Biochem. Physiol. Part A: Mol. Integr. Physiol.
  doi: 10.1016/j.cbpa.2015.03.009
  contributor:
    fullname: Yang
– volume: 23
  start-page: 12312
  issue: 12
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0260
  article-title: Cytotoxicity and alterations at transcriptional level caused by metals on fish erythrocytes in vitro
  publication-title: Environ. Sci. Pollut. Res.
  doi: 10.1007/s11356-016-6445-3
  contributor:
    fullname: Morcillo
– volume: 165
  start-page: 22
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0255
  article-title: Effects of predator odour on antipredator responses of Nile tilapia
  publication-title: Physiol. Behav.
  doi: 10.1016/j.physbeh.2016.06.033
  contributor:
    fullname: Miyai
– volume: 25
  start-page: 1426
  issue: 7
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0305
  article-title: Environmental concentration of carbamazepine accelerates fish embryonic development and disturbs larvae behavior
  publication-title: Ecotoxicology
  doi: 10.1007/s10646-016-1694-y
  contributor:
    fullname: Qiang
– volume: 236
  start-page: 633
  issue: 1
  year: 2004
  ident: 10.1016/j.aquatox.2017.09.017_bib0070
  article-title: Hypoxic conditions induce Hsp70 production in blood, brain and head kidney of juvenile nile tilapia Oreochromis niloticus (L.)
  publication-title: Aquaculture
  doi: 10.1016/j.aquaculture.2004.02.025
  contributor:
    fullname: Delaney
– volume: 32
  start-page: 1
  issue: 1
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0045
  article-title: Recent advances and prospects of catalytic advanced oxidation process in treating textile effluents
  publication-title: Rev. Chem. Eng.
  doi: 10.1515/revce-2015-0034
  contributor:
    fullname: Buthiyappan
– volume: 151
  start-page: 135
  year: 2004
  ident: 10.1016/j.aquatox.2017.09.017_bib0065
  article-title: Nitrogen isotope ratios of synthetic and organic sources of nitrate water contamination in spain
  publication-title: Water Air Soil Pollut.
  doi: 10.1023/B:WATE.0000009889.36833.c0
  contributor:
    fullname: Curt
– volume: 141
  start-page: 177
  issue: 1–3
  year: 2008
  ident: 10.1016/j.aquatox.2017.09.017_bib0405
  article-title: Monitoring pollution in River Mureă, Romania, part II: Metal accumulation and histopathology in fish
  publication-title: Environ. Monit. Assess.
  doi: 10.1007/s10661-007-9886-9
  contributor:
    fullname: Triebskorn
– volume: 38
  start-page: 244
  issue: 3
  year: 1997
  ident: 10.1016/j.aquatox.2017.09.017_bib0300
  article-title: Heat shock proteins (HSP70) as biomarkers in ecotoxicological studies
  publication-title: Ecotoxicol. Environ. Saf.
  doi: 10.1006/eesa.1997.1595
  contributor:
    fullname: Pyza
– volume: 112
  start-page: 335
  issue: 3
  year: 1995
  ident: 10.1016/j.aquatox.2017.09.017_bib0335
  article-title: Induction and subcellular localization of two major stress proteins in response to copper in the fathead minnow Pimephales promelas
  publication-title: Comp. Biochem. Physiol. Part C: Pharmacol. Toxicol. Endocrinol.
  contributor:
    fullname: Sanders
– volume: 6
  start-page: 249
  issue: 5
  year: 1997
  ident: 10.1016/j.aquatox.2017.09.017_bib0090
  article-title: The induction of stress proteins (hsp) in Oniscus asellus (Isopoda) as a molecular marker of multiple heavy metal exposure: I. Principles and toxicological assessment
  publication-title: Ecotoxicology
  doi: 10.1023/A:1018682928839
  contributor:
    fullname: Eckwert
– volume: 295
  start-page: 173
  issue: 2
  year: 2002
  ident: 10.1016/j.aquatox.2017.09.017_bib0015
  article-title: Heat shock protein genes and their functional significance in fish
  publication-title: Gene
  doi: 10.1016/S0378-1119(02)00687-X
  contributor:
    fullname: Basu
– volume: 72
  start-page: 248
  issue: 1–2
  year: 1976
  ident: 10.1016/j.aquatox.2017.09.017_bib0025
  article-title: A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
  publication-title: Anal. Biochem.
  doi: 10.1016/0003-2697(76)90527-3
  contributor:
    fullname: Bradford
– volume: 71
  start-page: 47
  year: 1987
  ident: 10.1016/j.aquatox.2017.09.017_bib0105
  article-title: The fish gill: site of action and model for toxic effects of environmental pollutants
  publication-title: Environ. Health Perspect.
  doi: 10.1289/ehp.877147
  contributor:
    fullname: Evans
– volume: 25
  start-page: 118
  year: 2013
  ident: 10.1016/j.aquatox.2017.09.017_bib0040
  article-title: The potential to reduce the risk of diffuse pollution from agriculture while improving economic performance at farm level
  publication-title: Environ. Sci. Policy
  doi: 10.1016/j.envsci.2012.10.002
  contributor:
    fullname: Buckley
– volume: 20
  start-page: 69
  issue: 1
  year: 1982
  ident: 10.1016/j.aquatox.2017.09.017_bib0160
  article-title: The effect of pre-fasting diet and water temperature on liver glycogen and liver weight in rainbow trout, Salmo gairdneri Richardson, during fasting
  publication-title: J. Fish Biol.
  doi: 10.1111/j.1095-8649.1982.tb03895.x
  contributor:
    fullname: Hilton
– start-page: 95
  year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0200
  article-title: Concept of stress and its mitigation in aquaculture
  contributor:
    fullname: Kumar
– volume: 174
  start-page: 180
  issue: 0
  year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0150
  article-title: Occurrence and assessment of perfluorinated compounds in fish from the Danjiangkou reservoir and Hanjiang river in China
  publication-title: Food Chem.
  doi: 10.1016/j.foodchem.2014.11.018
  contributor:
    fullname: He
– volume: 84
  start-page: 389
  issue: 3
  year: 1974
  ident: 10.1016/j.aquatox.2017.09.017_bib0380
  article-title: Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs
  publication-title: J. Mol. Biol.
  doi: 10.1016/0022-2836(74)90447-1
  contributor:
    fullname: Tissiéres
– volume: 8
  start-page: 261
  issue: 3–4
  year: 2001
  ident: 10.1016/j.aquatox.2017.09.017_bib0180
  article-title: The hepatic stress protein (hsp70) response to interacting abiotic parameters in fish exposed to various levels of pollution
  publication-title: J. Aquat. Ecosyst. Stress Recov.
  doi: 10.1023/A:1012935931161
  contributor:
    fullname: Köhler
– ident: 10.1016/j.aquatox.2017.09.017_bib0210
– volume: 283
  start-page: 1828
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0110
  article-title: Host behaviour–parasite feedback: an essential link between animal behaviour and disease ecology
  publication-title: Proc. R. Soc. B: Biol. Sci.
  doi: 10.1098/rspb.2015.3078
  contributor:
    fullname: Ezenwa
– volume: 127
  start-page: 51
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0330
  article-title: Alterations in gene expression levels provide early indicators of chemical stress during Xenopus laevis embryo development: a case study with perfluorooctane sulfonate (PFOS)
  publication-title: Ecotoxicol. Environ. Saf.
  doi: 10.1016/j.ecoenv.2016.01.005
  contributor:
    fullname: San-Segundo
– volume: 95
  start-page: 240
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0115
  article-title: Tracing the limits of organic micropollutant removal in biological wastewater treatment
  publication-title: Water Res.
  doi: 10.1016/j.watres.2016.03.009
  contributor:
    fullname: Falås
– volume: 40
  start-page: 363
  issue: 3
  year: 2001
  ident: 10.1016/j.aquatox.2017.09.017_bib0055
  article-title: Use of Japanese medaka (Oryzias latipes) and tilapia (Oreochromis mossambicus) in toxicity tests on different industrial effluents in Taiwan
  publication-title: Arch. Environ. Contam. Toxicol.
  doi: 10.1007/s002440010184
  contributor:
    fullname: Chen
– volume: 225
  start-page: 1877
  issue: 3
  year: 2014
  ident: 10.1016/j.aquatox.2017.09.017_bib0320
  article-title: Integrating micro-pollutant removal by powdered activated carbon into deep bed filtration
  publication-title: Water Air Soil Pollut.
  doi: 10.1007/s11270-014-1877-1
  contributor:
    fullname: Ruhl
– volume: 26
  start-page: 580
  issue: 3
  year: 2009
  ident: 10.1016/j.aquatox.2017.09.017_bib0440
  article-title: Towards the implementation of the European water framework directive?
  publication-title: Land Use Policy
  doi: 10.1016/j.landusepol.2008.08.005
  contributor:
    fullname: Volk
– volume: 157
  start-page: 370
  issue: 4
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0290
  article-title: Reaktionen von Flohkrebsen und Makrozoobenthos auf die Nachröstung einer Klüranlage mit einer Pulveraktivkohlestufe
  publication-title: gwf − Wasser/Abwasser
  doi: 10.17560/gwfwa.v157i04.1783
  contributor:
    fullname: Peschke
– start-page: 1
  year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0430
  article-title: Impact of wastewater on fish health: a case study at the Neckar River (Southern Germany) using biomarkers in caged brown trout as assessment tools
  publication-title: Environ. Sci. Pollut. Res.
  contributor:
    fullname: Vincze
– volume: 124
  start-page: 181
  issue: 2
  year: 1999
  ident: 10.1016/j.aquatox.2017.09.017_bib0080
  article-title: Comparative baseline levels of mercury, Hsp70 and Hsp60 in subsistence fish from the Yukon-Kuskokwim delta region of Alaska
  publication-title: Comp. Biochem. Physiol. Part C: Pharmacol. Toxicol. Endocrinol.
  contributor:
    fullname: Duffy
– volume: 219
  start-page: 3712
  issue: 23
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0250
  article-title: Stress and food deprivation: linking physiological state to migration success in a teleost fish
  publication-title: J. Exp. Biol.
  doi: 10.1242/jeb.140665
  contributor:
    fullname: Midwood
– volume: 595
  start-page: 711
  year: 2017
  ident: 10.1016/j.aquatox.2017.09.017_bib0010
  article-title: Multi-biomarker responses in fish (Jenynsia multidentata) to assess the impact of pollution in rivers with mixtures of environmental contaminants
  publication-title: Sci. Total Environ.
  doi: 10.1016/j.scitotenv.2017.03.203
  contributor:
    fullname: Ballesteros
– volume: 189
  start-page: 87
  year: 2017
  ident: 10.1016/j.aquatox.2017.09.017_bib0265
  article-title: Diclofenac affects kidney histology in the three-spined stickleback (Gasterosteus aculeatus) at low (g/L concentrations
  publication-title: Aquat. Toxicol.
  doi: 10.1016/j.aquatox.2017.05.017
  contributor:
    fullname: Näslund
– volume: 7
  issue: 9
  year: 2014
  ident: 10.1016/j.aquatox.2017.09.017_bib0415
  article-title: Die Kläranlage Albstadt-Ebingen: Aktivkohlefilterung im Vollstrom seit 1992-Ein langfristiger Erfolg für die Fischgesundheit und die Gewässerökologie
  publication-title: Korrespondenz Wasserwirtschaft.
  contributor:
    fullname: Triebskorn
– volume: 6
  start-page: 75
  issue: 1
  year: 1997
  ident: 10.1016/j.aquatox.2017.09.017_bib0345
  article-title: The use of histopathological indicators to evaluate contaminant-related stress in fish
  publication-title: J. Aquat. Ecosyst. Stress Recov.
  doi: 10.1023/A:1008212000208
  contributor:
    fullname: Schwaiger
– volume: 68
  start-page: 151
  issue: 2
  year: 2004
  ident: 10.1016/j.aquatox.2017.09.017_bib0395
  article-title: Toxic effects of the non-steroidal anti-inflammatory drug diclofenac: part II. Cytological effects in liver, kidney, gills and intestine of rainbow trout (Oncorhynchus mykiss)
  publication-title: Aquat. Toxicol.
  doi: 10.1016/j.aquatox.2004.03.015
  contributor:
    fullname: Triebskorn
– volume: 313
  start-page: 1072
  issue: 5790
  year: 2006
  ident: 10.1016/j.aquatox.2017.09.017_bib0355
  article-title: The challenge of micropollutants in aquatic systems
  publication-title: Science
  doi: 10.1126/science.1127291
  contributor:
    fullname: Schwarzenbach
– volume: 100
  start-page: 580
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0190
  article-title: Elimination of micropollutants and transformation products from a wastewater treatment plant effluent through pilot scale ozonation followed by various activated carbon and biological filters
  publication-title: Water Res.
  doi: 10.1016/j.watres.2016.04.069
  contributor:
    fullname: Knopp
– volume: 248
  start-page: 186
  issue: 1
  year: 1997
  ident: 10.1016/j.aquatox.2017.09.017_bib0285
  article-title: A simplified procedure for a rapid and reliable assay of both glycogen and trehalose in whole yeast cells
  publication-title: Anal. Biochem.
  doi: 10.1006/abio.1997.2138
  contributor:
    fullname: Parrou
– volume: 8
  start-page: 241
  issue: 3–4
  year: 2001
  ident: 10.1016/j.aquatox.2017.09.017_bib0130
  article-title: Ultrastructural biomarkers as tools to characterize the health status of fish in contaminated streams
  publication-title: J. Aquat. Ecosyst. Stress Recov.
  doi: 10.1023/A:1012958804442
  contributor:
    fullname: Gernhöfer
– start-page: 65
  year: 1979
  ident: 10.1016/j.aquatox.2017.09.017_bib0165
  article-title: A simple sequentially rejective multiple test procedure
  publication-title: Scand. J. Stat.
  contributor:
    fullname: Holm
– start-page: 65
  year: 2017
  ident: 10.1016/j.aquatox.2017.09.017_bib0005
  article-title: Organic micropollutants in the environment: ecotoxicity potential and methods for remediation
  contributor:
    fullname: Arslan
– start-page: 77
  year: 1996
  ident: 10.1016/j.aquatox.2017.09.017_bib0035
  article-title: The structure and function of fish liver
  publication-title: Fish Morphol.
  contributor:
    fullname: Brusle
– volume: vol. 86
  start-page: 61
  year: 1998
  ident: 10.1016/j.aquatox.2017.09.017_bib0030
  article-title: Cytological alterations in fish hepatocytes following in vivo and in vitro sublethal exposure to xenobiotics—structural biomarkers of environmental contamination
  contributor:
    fullname: Braunbeck
– ident: 10.1016/j.aquatox.2017.09.017_bib0175
– volume: 74
  start-page: 452
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0220
  article-title: Integrating taxonomic and trait analyses to assess the impact of damming on fish communities in a northern cold region river
  publication-title: Can. J. Fish. Aquat.Sci.
  doi: 10.1139/cjfas-2016-0074
  contributor:
    fullname: Lima
– volume: 132–133
  start-page: 200
  year: 2013
  ident: 10.1016/j.aquatox.2017.09.017_bib0120
  article-title: Chronic, low concentration exposure to pharmaceuticals impacts multiple organ systems in zebrafish
  publication-title: Aquat. Toxicol.
  doi: 10.1016/j.aquatox.2012.12.021
  contributor:
    fullname: Galus
– volume: 3
  issue: 2
  year: 2017
  ident: 10.1016/j.aquatox.2017.09.017_bib0370
  article-title: Does waste water treatment plant upgrading with powdered activated carbon result in reduced water and sediment toxicity of the receiving stream
  publication-title: Int. J. Water Wastewater Treat.
  contributor:
    fullname: Thellmann
– ident: 10.1016/j.aquatox.2017.09.017_bib0085
– volume: 2
  start-page: 457
  issue: 5
  year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0235
  article-title: A review of the fate of micropollutants in wastewater treatment plants
  publication-title: Wiley Interdiscip. Rev.: Water
  doi: 10.1002/wat2.1090
  contributor:
    fullname: Margot
– ident: 10.1016/j.aquatox.2017.09.017_bib0100
– volume: 56
  start-page: 442
  issue: 3
  year: 2003
  ident: 10.1016/j.aquatox.2017.09.017_bib0315
  article-title: Micronucleus test in freshwater fish species: an evaluation of its sensitivity for application in field surveys
  publication-title: Ecotoxicol. Environ. Saf.
  doi: 10.1016/S0147-6513(03)00073-3
  contributor:
    fullname: Rodriguez-Cea
– volume: 22
  start-page: 16405
  issue: 21
  year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0365
  article-title: Fish embryo tests with Danio rerio as a tool to evaluate surface water and sediment quality in rivers influenced by wastewater treatment plants using different treatment technologies
  publication-title: Environ. Sci. Pollut. Res.
  doi: 10.1007/s11356-014-3785-8
  contributor:
    fullname: Thellmann
– volume: 11
  start-page: 451
  issue: 6
  year: 2002
  ident: 10.1016/j.aquatox.2017.09.017_bib0390
  article-title: Biomarkers as diagnostic tools for evaluating effects of unknown past water quality conditions on stream organisms
  publication-title: Ecotoxicology
  doi: 10.1023/A:1021009418421
  contributor:
    fullname: Triebskorn
– volume: 9
  start-page: e98307
  issue: 6
  year: 2014
  ident: 10.1016/j.aquatox.2017.09.017_bib0155
  article-title: Are in vitro methods for the detection of endocrine potentials in the aquatic environment predictive for in vivo effects? Outcomes of the projects SchussenAktiv and SchussenAktivplus in the Lake Constance area, Germany
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0098307
  contributor:
    fullname: Henneberg
– ident: 10.1016/j.aquatox.2017.09.017_bib0435
– volume: 154
  start-page: 254
  issue: 3
  year: 2011
  ident: 10.1016/j.aquatox.2017.09.017_bib0445
  article-title: Aroclor 1254 disrupts liver glycogen metabolism and enhances acute stressor-mediated glycogenolysis in rainbow trout
  publication-title: Comp. Biochem. Physiol. − Part C: Toxicol. Pharmacol.
  contributor:
    fullname: Wiseman
– volume: 91
  start-page: 97
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0240
  article-title: The benefits of powdered activated carbon recirculation for micropollutant removal in advanced wastewater treatment
  publication-title: Water Res.
  doi: 10.1016/j.watres.2016.01.009
  contributor:
    fullname: Meinel
– volume: 34
  start-page: 284
  issue: 5
  year: 2014
  ident: 10.1016/j.aquatox.2017.09.017_bib0450
  article-title: The use of spontaneous behavior, swimming performances and metabolic rate to evaluate toxicity of PFOS on topmouth gudgeon Pseudorasbora parva
  publication-title: Acta Ecol. Sin.
  doi: 10.1016/j.chnaes.2014.07.006
  contributor:
    fullname: Xia
– ident: 10.1016/j.aquatox.2017.09.017_bib0095
– volume: 16
  start-page: 271
  issue: 4
  year: 1990
  ident: 10.1016/j.aquatox.2017.09.017_bib0185
  article-title: Identification of contaminant-induced cellular and subcellular lesions in the liver of flounder (Platichthys flesus L.) caught at differently polluted estuaries
  publication-title: Aquat. Toxicol.
  doi: 10.1016/0166-445X(90)90041-M
  contributor:
    fullname: Köhler
– volume: 34
  start-page: 757
  issue: 5
  year: 1989
  ident: 10.1016/j.aquatox.2017.09.017_bib0295
  article-title: Differences in the sensitivity of brown trout, Salmo trutta L., and rainbow trout, Salmo gairdneri Richardson, to physiological doses of cortisol
  publication-title: J. Fish Biol.
  doi: 10.1111/j.1095-8649.1989.tb03355.x
  contributor:
    fullname: Pickering
– volume: 6
  start-page: 57
  issue: 1
  year: 1997
  ident: 10.1016/j.aquatox.2017.09.017_bib0385
  article-title: Induction of heat shock proteins, changes in liver ultrastructure, and alterations of fish behavior: are these biomarkers related and are they useful to reflect the state of pollution in the field?
  publication-title: J. Aquat. Ecosyst. Stress Recov.
  doi: 10.1023/A:1008224301117
  contributor:
    fullname: Triebskorn
– volume: 14
  start-page: 1375
  issue: 5
  year: 2012
  ident: 10.1016/j.aquatox.2017.09.017_bib0245
  article-title: Ecological risk assessment of perfluorooctanoic acid (PFOA) and perfluorooctanesulfonic acid (PFOS) in marine environment using Isochrysis galbana, Paracentrotus lividus, Siriella armata and Psetta maxima
  publication-title: J. Environ. Monit.
  doi: 10.1039/c2em30037k
  contributor:
    fullname: Mhadhbi
– volume: 293
  start-page: 320
  issue: 3
  year: 2002
  ident: 10.1016/j.aquatox.2017.09.017_bib0275
  article-title: Gill circulation: regulation of perfusion distribution and metabolism of regulatory molecules
  publication-title: J. Exp. Zool.
  doi: 10.1002/jez.10126
  contributor:
    fullname: Olson
– volume: 132
  start-page: 47
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0230
  article-title: Reduction of dioxin-like toxicity in effluents by additional wastewater treatment and related effects in fish
  publication-title: Ecotoxicol. Environ. Saf.
  doi: 10.1016/j.ecoenv.2016.04.036
  contributor:
    fullname: Maier
– year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0020
  contributor:
    fullname: Birzle
– volume: 155
  start-page: 456
  issue: 3
  year: 2012
  ident: 10.1016/j.aquatox.2017.09.017_bib0270
  article-title: Copper and the herbicide atrazine impair the stress response of the freshwater fish Prochilodus lineatus
  publication-title: Comp. Biochem. Physiol.—Part C: Toxicol. Pharmacol.
  contributor:
    fullname: Nascimento
– volume: 31
  start-page: 106
  issue: 1
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0205
  article-title: Cellular metabolic, stress, and histological response on exposure to acute toxicity of endosulfan in Tilapia (Oreochromis mossambicus)
  publication-title: Environ. Toxicol.
  doi: 10.1002/tox.22026
  contributor:
    fullname: Kumar
– volume: 227
  start-page: 1
  issue: 3
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0195
  article-title: Genotoxic and histopathological effects of olive-mill wastewater on Lepomis gibbosus
  publication-title: Water Air Soil Pollut.
  doi: 10.1007/s11270-016-2769-3
  contributor:
    fullname: Koca
– volume: 6
  start-page: 1025
  issue: 11
  year: 2003
  ident: 10.1016/j.aquatox.2017.09.017_bib0325
  article-title: The evolutionary and ecological role of heat shock proteins
  publication-title: Ecol. Lett.
  doi: 10.1046/j.1461-0248.2003.00528.x
  contributor:
    fullname: Sørensen
– ident: 10.1016/j.aquatox.2017.09.017_bib0420
– volume: 5
  start-page: 327
  year: 2007
  ident: 10.1016/j.aquatox.2017.09.017_bib0050
  article-title: Histopathology of gills, kidney and liver of a Neotropical fish caged in an urban stream
  publication-title: Neotrop. Ichthyol.
  doi: 10.1590/S1679-62252007000300013
  contributor:
    fullname: Camargo
– volume: 32
  start-page: 147
  issue: 1
  year: 2015
  ident: 10.1016/j.aquatox.2017.09.017_bib0125
  article-title: Emerging pollutants in the environment: present and future challenges in biomonitoring, ecological risks and bioremediation
  publication-title: New Biotechnol.
  doi: 10.1016/j.nbt.2014.01.001
  contributor:
    fullname: Gavrilescu
– volume: 73
  start-page: 353
  issue: 3
  year: 2008
  ident: 10.1016/j.aquatox.2017.09.017_bib0140
  article-title: Acute effects of diclofenac and DMSO to Daphnia magna: immobilisation and hsp70-induction
  publication-title: Chemosphere
  doi: 10.1016/j.chemosphere.2008.05.062
  contributor:
    fullname: Haap
– volume: 11
  start-page: 2072
  issue: 14
  year: 2005
  ident: 10.1016/j.aquatox.2017.09.017_bib0215
  article-title: Expression of heat shock proteins (HSP27, HSP60, HSP70, HSP90, GRP78, GRP94) in hepatitis B virus-related hepatocellular carcinomas and dysplastic nodules
  publication-title: World J. Gastroenterol.
  doi: 10.3748/wjg.v11.i14.2072
  contributor:
    fullname: Lim
– volume: 74
  start-page: 723
  issue: 5
  year: 2009
  ident: 10.1016/j.aquatox.2017.09.017_bib0075
  article-title: Chronic effects of water-borne PFOS exposure on growth, survival and hepatotoxicity in zebrafish: a partial life-cycle test
  publication-title: Chemosphere
  doi: 10.1016/j.chemosphere.2008.09.075
  contributor:
    fullname: Du
– volume: 31
  start-page: 110
  issue: 2
  year: 2016
  ident: 10.1016/j.aquatox.2017.09.017_bib0280
  article-title: A review of ecological restoration techniques in fluvial rivers, International
  publication-title: J. Sediment. Res.
  doi: 10.1016/j.ijsrc.2016.03.001
  contributor:
    fullname: Pan
SSID ssj0000249
Score 2.3782482
Snippet •Incomplete removal of micropollutants by conventional wastewater treatment.•Efficiency of an additional powdered activated carbon filter unit was...
In the present study, the efficiency of a wastewater treatment plant (WWTP) upgraded with a powdered activated carbon unit for the reduction of micropollutants...
SourceID hal
crossref
pubmed
elsevier
SourceType Open Access Repository
Aggregation Database
Index Database
Publisher
StartPage 184
SubjectTerms Animals
Biodiversity and Ecology
Biomarkers
Charcoal - chemistry
Environmental Sciences
Gene Expression Regulation - drug effects
Glycogen
Histopathology
hsp70
Micropollutants
Oncorhynchus mykiss - physiology
Waste Disposal Facilities - standards
Waste Water - chemistry
Water Pollutants, Chemical - chemistry
Water Pollutants, Chemical - toxicity
Water Purification - methods
Water Purification - standards
Title Does wastewater treatment plant upgrading with activated carbon result in an improvement of fish health?
URI https://dx.doi.org/10.1016/j.aquatox.2017.09.017
https://www.ncbi.nlm.nih.gov/pubmed/28965022
https://univ-avignon.hal.science/hal-02047744
Volume 192
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1La9wwEB7SlNJeQpO-to8gSq7eXcmWbJ3Csk3Y9JFLGtibkGW56xC8232kzSW_vTOyvSFQKPRkW8jIfBpG38jzjQCOhJNWe5dHcSZ9lCjlIp1ZFTmb8VLEccw5aYe_navJZfJ5Kqc7MO60MJRW2fr-xqcHb922DFo0B4uqGlwgWcHFXE45GqlQkoTmVGwLbbp_d5_mQSXxmvreKqLe9yqewVXf_txgaPubMrzSUO40nFv21_Xp0YwSJR9Qz7AEnT6HvZY7slHzefuw4-sDeDrujmw7gCcnoQb17QuYfZr7FftlV7Q3htCxbUI5W1wjmGyz-LEM6fOMdmIZyRtusGPBnF3m85phFL65XrOqZrZmVdh5CBuJbF6yslrNWCOgPH4Jl6cn38eTqD1UIXIY-a2jPM8TnlqnVeE8_RrJC7z1EgFxMkkLrrUrvdRS-LRMhz6VKsuRRWVIvZxLi_gV7Nbz2r8B5nSGwV4inEpVwjm6cDvk1vuhFgINNO5Bv4PSLJraGaZLKrsyLfaGsDdDbfDSg6wD3DwwAoP-_V-vfsQJ2g5DRbMno6-G2kj-iyQ3ueE9eN3M37YfhptIUYV4-_8jv4Nn9NToE9_D7nq58R-QqKzzw2CJh_B4dPZlcv4HB9zoYA
link.rule.ids 230,315,783,787,888,4511,24130,27938,27939,45599,45693
linkProvider Elsevier
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3dT9swED_xoQlepsE2KNuYNfGatnZiJ35CqAOVrfACSH2zHMehQSgt_YDxwt_O2UmKkCYh8ZTIucjRz6fz7y53Z4ADZriW1qRBmHAbREKYQCZaBEYnNGdhGFLqaofPzkX_Kvoz5MMV6DW1MC6tsrb9lU331roe6dRodiZF0blAsoKbOR9SVFImOF-F9cj1z0Klbj-95Hm4nnhVg28ROPGXMp7OTVvfLdC3_edSvGLf79QfXPbfDWp15DIlX3FPvwedfIKPNXkkR9X3bcGKLbdho9ec2bYNH459E-rHzzD6PbYz8qBnLjiG2JFlRjmZ3CKaZDG5nvr8eeJCscTVN9yjYEaMnqbjkqAbvridk6IkuiSFDz34SCIZ5yQvZiNSVVAefoGrk-PLXj-oT1UIDLp-8yBN04jG2kiRGev-jaQZ3lqOgBgexRmV0uSWS85snMddG3ORpEijEuRexsRZ-BXWynFpd4EYmaC3FzEjYhFRijZcd6m2tisZQw0NW9BuoFSTqnmGarLKblSNvXLYq65UeGlB0gCuXmmBQgP_1qu_cIGW07iu2f2jgXJjrv4XWW50T1uwU63fUg79TeSojO29f-afsNG_PBuowen532-w6Z5UxYrfYW0-XdgfyFrm6b7XymeaMOoC
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Does+wastewater+treatment+plant+upgrading+with+activated+carbon+result+in+an+improvement+of+fish+health%3F&rft.jtitle=Aquatic+toxicology&rft.au=Wilhelm%2C+Sabrina&rft.au=Henneberg%2C+Anja&rft.au=K%C3%B6hler%2C+Heinz-R.&rft.au=Rault%2C+Magali&rft.date=2017-11-01&rft.pub=Elsevier+B.V&rft.issn=0166-445X&rft.eissn=1879-1514&rft.volume=192&rft.spage=184&rft.epage=197&rft_id=info:doi/10.1016%2Fj.aquatox.2017.09.017&rft.externalDocID=S0166445X17302655
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0166-445X&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0166-445X&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0166-445X&client=summon