Value of Remission in Patients with Rheumatoid Arthritis: A Targeted Review
The treat-to-target strategy, which defines clinical remission as the primary therapeutic goal for rheumatoid arthritis (RA), is a widely recommended treatment approach in clinical guidelines. Achieving remission has been associated with improved clinical outcomes, quality of life, and productivity....
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Published in | Advances in therapy Vol. 39; no. 1; pp. 75 - 93 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
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Cheshire
Springer Healthcare
01.01.2022
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Abstract | The treat-to-target strategy, which defines clinical remission as the primary therapeutic goal for rheumatoid arthritis (RA), is a widely recommended treatment approach in clinical guidelines. Achieving remission has been associated with improved clinical outcomes, quality of life, and productivity. These benefits are likely to translate to reduced economic burden in terms of lower healthcare costs and resource utilization. As such, a literature review was conducted to better understand the economic value of remission. Despite the large heterogeneity found in RA-related economic outcomes across studies, patients in remission consistently had lower direct medical and indirect costs, less healthcare resource utilization, and greater productivity compared to those without remission. Remission was associated with 19–52% savings in direct medical costs and 37–75% savings in indirect costs. The economic value of remission should thus be considered in economic analyses of RA therapies to inform treatment and reimbursement decisions. |
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AbstractList | The treat-to-target strategy, which defines clinical remission as the primary therapeutic goal for rheumatoid arthritis (RA), is a widely recommended treatment approach in clinical guidelines. Achieving remission has been associated with improved clinical outcomes, quality of life, and productivity. These benefits are likely to translate to reduced economic burden in terms of lower healthcare costs and resource utilization. As such, a literature review was conducted to better understand the economic value of remission. Despite the large heterogeneity found in RA-related economic outcomes across studies, patients in remission consistently had lower direct medical and indirect costs, less healthcare resource utilization, and greater productivity compared to those without remission. Remission was associated with 19-52% savings in direct medical costs and 37-75% savings in indirect costs. The economic value of remission should thus be considered in economic analyses of RA therapies to inform treatment and reimbursement decisions. |
Author | Nagy, Orsolya Betts, Keith A. Ostor, Andrew J. Wu, Aozhou Qi, Cynthia Z. Sawant, Ruta |
Author_xml | – sequence: 1 givenname: Andrew J. surname: Ostor fullname: Ostor, Andrew J. organization: Cabrini Medical Center, Monash University and Emeritus Research – sequence: 2 givenname: Ruta surname: Sawant fullname: Sawant, Ruta organization: AbbVie, Inc – sequence: 3 givenname: Cynthia Z. surname: Qi fullname: Qi, Cynthia Z. organization: Analysis Group, Inc – sequence: 4 givenname: Aozhou surname: Wu fullname: Wu, Aozhou organization: Analysis Group, Inc – sequence: 5 givenname: Orsolya surname: Nagy fullname: Nagy, Orsolya organization: AbbVie, Inc – sequence: 6 givenname: Keith A. surname: Betts fullname: Betts, Keith A. email: keith.betts@analysisgroup.com organization: Analysis Group, Inc |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34787822$$D View this record in MEDLINE/PubMed |
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CitedBy_id | crossref_primary_10_1007_s11882_023_01118_6 crossref_primary_10_1016_j_berh_2024_101940 crossref_primary_10_1007_s00296_023_05444_w crossref_primary_10_1007_s40744_022_00473_6 |
Cites_doi | 10.1007/s10067-019-04600-7 10.1002/art.39079 10.3310/hta21710 10.3899/jrheum.100589 10.1136/annrheumdis-2013-204021 10.3899/jrheum.131449 10.4061/2011/727634 10.1002/acr.22678 10.5114/aoms.2018.73714 10.1007/s00296-019-04352-2 10.1136/annrheumdis-2015-207524 10.1136/annrheumdis-2013-203339 10.1002/pds.4126 10.1007/s12325-020-01303-3 10.1093/rheumatology/keq327 10.1136/annrheumdis-2016-210715 10.1080/14397595.2017.1416940 10.3904/kjim.2015.30.3.384 10.2147/JIR.S219586 10.3389/fmed.2018.00040 10.1136/annrheumdis-2013-204906 10.1001/jama.2018.13103 10.1002/acr.20021 10.1080/03007995.2016.1222515 10.1016/j.rdc.2009.10.001 10.2147/CEOR.S263903 10.1186/ar1787 10.1007/s00296-017-3739-9 10.1186/s13075-015-0707-1 10.1136/annrheumdis-2014-207080 10.2174/1874312901206010038 10.1136/annrheumdis-2012-201918 10.1007/s10067-016-3470-z 10.1016/S0140-6736(04)16676-2 10.1186/1471-2474-14-350 10.3389/fmed.2018.00185 10.1136/ard.2010.149260 10.1007/s10067-010-1534-z 10.1136/ard.2011.149765 10.1186/ar2951 10.1186/ar4491 10.1177/1759720X17720366 10.1002/acr.22048 10.3899/jrheum.161404 10.1186/s41927-019-0054-y 10.1186/s13075-015-0719-x 10.1002/acr.22783 10.1093/rheumatology/keq444 |
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Keywords | Economic benefit Rheumatoid arthritis Healthcare resource utilization Remission Treat-to-target Indirect cost Direct cost |
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References | Curtis, Chen, Greenberg (CR47) 2017; 26 van Tuyl, Felson, Wells (CR15) 2010; 62 Alemao, Joo, Kawabata (CR24) 2016; 68 Kim, Kaneko, Takeuchi (CR49) 2017; 44 Sokka, Kautiainen, Pincus (CR2) 2010; 12 Ajeganova, van Steenbergen, van Nies, Burgers, Huizinga, van der Helm-van Mil (CR30) 2016; 75 Klarenbeek, Koevoets, van der Heijde (CR13) 2011; 70 Hallert, Husberg, Skogh (CR44) 2011; 50 Weijers, Baerwald, Mennini (CR55) 2017; 37 Gullick, Ibrahim, Scott (CR25) 2019; 3 Yazdany, Dudley, Chen, Lin, Tseng (CR51) 2015; 67 Husberg, Davidson, Hallert (CR50) 2017; 36 Nagy, van Vollenhoven (CR21) 2015; 17 Radner, Smolen, Aletaha (CR14) 2014; 16 Vander Cruyssen, Van Looy, Wyns (CR11) 2005; 7 Pope, Sawant, Tundia (CR5) 2020; 37 Smolen, Breedveld, Burmester (CR3) 2016; 75 Park, Han, Lobo, Nanji, Patel (CR54) 2020; 12 Beresniak, Gossec, Goupille (CR38) 2011; 38 CR6 Wailoo, Hock, Stevenson (CR18) 2017; 21 CR9 Listing, Kekow, Manger (CR27) 2015; 74 Curtis, Shan, Harrold, Zhang, Greenberg, Reed (CR32) 2013; 65 Beresniak, Baerwald, Zeidler (CR37) 2013; 31 Aletaha, Smolen (CR1) 2018; 320 Gronning, Rodevand, Steinsbekk (CR35) 2010; 29 Singh, Saag, Bridges (CR7) 2016; 68 Gul, Eugenio, Rabin (CR10) 2020; 59 Orr, Najm, Young (CR12) 2018; 5 Barnabe, Thanh, Ohinmaa (CR45) 2013; 72 Canhao, Rodrigues, Gregorio (CR8) 2018; 5 Ajeganova, Huizinga (CR20) 2017; 9 Beresniak, Ariza-Ariza, Garcia-Llorente, Ramirez-Arellano, Dupont (CR36) 2011; 2011 Radner, Alasti, Smolen, Aletaha (CR28) 2015; 17 Boytsov, Harrold, Mason (CR48) 2016; 32 Ishida, Kuroiwa, Yoshida (CR31) 2018; 28 Ten Klooster, Oude Voshaar, Fakhouri, de la Torre, Nicolay, van de Laar (CR43) 2019; 38 Miranda, Santos, Ferreira (CR40) 2012; 37 Barnabe, Thanh, Ohinmaa (CR46) 2014; 41 Scire, Lunt, Marshall, Symmons, Verstappen (CR26) 2014; 73 Ruyssen-Witrand, Guernec, Nigon (CR29) 2015; 74 Son, Choi, Lee (CR34) 2015; 30 Ma, Li, Liu, Zhou, Zhou (CR16) 2019; 15 Vermeer, Kievit, Kuper (CR17) 2013; 14 Cimmino, Leardini, Salaffi (CR39) 2011; 29 Neubauer, Minartz, Herrmann, Baerwald (CR41) 2018; 36 Harrington, Al Nokhatha, Conway (CR52) 2020; 13 Grigor, Capell, Stirling (CR19) 2004; 364 Smolen, Landewe, Bijlsma (CR4) 2017; 76 CR23 Felson, Smolen, Wells (CR22) 2011; 70 Puolakka, Blafield, Kauppi (CR42) 2012; 6 Foo, Morel, Bergman (CR53) 2019; 39 Kekow, Moots, Khandker, Melin, Freundlich, Singh (CR33) 2011; 50 D Kim (1946_CR49) 2017; 44 A Beresniak (1946_CR36) 2011; 2011 R Harrington (1946_CR52) 2020; 13 NJ Gullick (1946_CR25) 2019; 3 M Vermeer (1946_CR17) 2013; 14 JA Singh (1946_CR7) 2016; 68 CK Orr (1946_CR12) 2018; 5 LH van Tuyl (1946_CR15) 2010; 62 M Husberg (1946_CR50) 2017; 36 C Barnabe (1946_CR45) 2013; 72 DT Felson (1946_CR22) 2011; 70 JS Smolen (1946_CR4) 2017; 76 G Nagy (1946_CR21) 2015; 17 J Pope (1946_CR5) 2020; 37 1946_CR9 K Ma (1946_CR16) 2019; 15 1946_CR6 NB Klarenbeek (1946_CR13) 2011; 70 J Listing (1946_CR27) 2015; 74 LC Miranda (1946_CR40) 2012; 37 E Alemao (1946_CR24) 2016; 68 A Beresniak (1946_CR38) 2011; 38 S Ajeganova (1946_CR30) 2016; 75 A Beresniak (1946_CR37) 2013; 31 K Puolakka (1946_CR42) 2012; 6 M Ishida (1946_CR31) 2018; 28 SH Park (1946_CR54) 2020; 12 CA Scire (1946_CR26) 2014; 73 AS Neubauer (1946_CR41) 2018; 36 J Yazdany (1946_CR51) 2015; 67 T Sokka (1946_CR2) 2010; 12 B Vander Cruyssen (1946_CR11) 2005; 7 S Ajeganova (1946_CR20) 2017; 9 H Radner (1946_CR14) 2014; 16 J Kekow (1946_CR33) 2011; 50 A Ruyssen-Witrand (1946_CR29) 2015; 74 K Gronning (1946_CR35) 2010; 29 CN Son (1946_CR34) 2015; 30 D Aletaha (1946_CR1) 2018; 320 H Canhao (1946_CR8) 2018; 5 1946_CR23 L Weijers (1946_CR55) 2017; 37 PM Ten Klooster (1946_CR43) 2019; 38 N Boytsov (1946_CR48) 2016; 32 A Wailoo (1946_CR18) 2017; 21 C Grigor (1946_CR19) 2004; 364 JR Curtis (1946_CR32) 2013; 65 C Barnabe (1946_CR46) 2014; 41 H Radner (1946_CR28) 2015; 17 J Foo (1946_CR53) 2019; 39 HL Gul (1946_CR10) 2020; 59 MA Cimmino (1946_CR39) 2011; 29 E Hallert (1946_CR44) 2011; 50 JS Smolen (1946_CR3) 2016; 75 JR Curtis (1946_CR47) 2017; 26 |
References_xml | – volume: 70 start-page: 1815 issue: 10 year: 2011 end-page: 1821 ident: CR13 article-title: Association with joint damage and physical functioning of nine composite indices and the 2011 ACR/EULAR remission criteria in rheumatoid arthritis publication-title: Ann Rheum Dis contributor: fullname: van der Heijde – volume: 364 start-page: 263 issue: 9430 year: 2004 end-page: 269 ident: CR19 article-title: Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial publication-title: Lancet contributor: fullname: Stirling – volume: 2011 year: 2011 ident: CR36 article-title: Modelling cost-effectiveness of biologic treatments based on disease activity scores for the management of rheumatoid arthritis in Spain publication-title: Int J Inflamm. contributor: fullname: Dupont – volume: 68 start-page: 308 issue: 3 year: 2016 end-page: 317 ident: CR24 article-title: Effects of achieving target measures in rheumatoid arthritis on functional status, quality of life, and resource utilization: analysis of clinical practice data publication-title: Arthritis Care Res (Hoboken) contributor: fullname: Kawabata – volume: 74 start-page: 415 issue: 2 year: 2015 end-page: 421 ident: CR27 article-title: Mortality in rheumatoid arthritis: the impact of disease activity, treatment with glucocorticoids, TNFalpha inhibitors and rituximab publication-title: Ann Rheum Dis contributor: fullname: Manger – volume: 320 start-page: 1360 issue: 13 year: 2018 end-page: 1372 ident: CR1 article-title: Diagnosis and management of rheumatoid arthritis: a review publication-title: JAMA contributor: fullname: Smolen – volume: 17 start-page: 181 year: 2015 ident: CR21 article-title: Sustained biologic-free and drug-free remission in rheumatoid arthritis, where are we now? publication-title: Arthritis Res Ther contributor: fullname: van Vollenhoven – volume: 38 start-page: 439 issue: 3 year: 2011 end-page: 445 ident: CR38 article-title: Direct cost-modeling of rheumatoid arthritis according to disease activity categories in France publication-title: J Rheumatol contributor: fullname: Goupille – volume: 50 start-page: 1259 issue: 7 year: 2011 end-page: 1267 ident: CR44 article-title: 28-Joint count disease activity score at 3 months after diagnosis of early rheumatoid arthritis is strongly associated with direct and indirect costs over the following 4 years: the Swedish TIRA project publication-title: Rheumatology (Oxford) contributor: fullname: Skogh – volume: 17 start-page: 203 year: 2015 ident: CR28 article-title: Physical function continues to improve when clinical remission is sustained in rheumatoid arthritis patients publication-title: Arthritis Res Ther contributor: fullname: Aletaha – volume: 37 start-page: 1111 issue: 7 year: 2017 end-page: 1123 ident: CR55 article-title: Cost per response for abatacept versus adalimumab in rheumatoid arthritis by ACPA subgroups in Germany, Italy, Spain, US and Canada publication-title: Rheumatol Int contributor: fullname: Mennini – volume: 74 start-page: 1676 issue: 9 year: 2015 end-page: 1683 ident: CR29 article-title: Aiming for SDAI remission versus low disease activity at 1 year after inclusion in ESPOIR cohort is associated with better 3-year structural outcomes publication-title: Ann Rheum Dis contributor: fullname: Nigon – volume: 50 start-page: 401 issue: 2 year: 2011 end-page: 409 ident: CR33 article-title: Improvements in patient-reported outcomes, symptoms of depression and anxiety, and their association with clinical remission among patients with moderate-to-severe active early rheumatoid arthritis publication-title: Rheumatology (Oxford) contributor: fullname: Singh – volume: 6 start-page: 38 year: 2012 end-page: 43 ident: CR42 article-title: Cost-effectiveness modelling of sequential biologic strategies for the treatment of moderate to severe rheumatoid arthritis in Finland publication-title: Open Rheumatol J contributor: fullname: Kauppi – volume: 67 start-page: 1474 issue: 6 year: 2015 end-page: 1480 ident: CR51 article-title: Coverage for high-cost specialty drugs for rheumatoid arthritis in Medicare Part D publication-title: Arthritis Rheumatol contributor: fullname: Tseng – volume: 37 start-page: 2356 issue: 5 year: 2020 end-page: 2372 ident: CR5 article-title: Comparative efficacy of JAK inhibitors for moderate-to-severe rheumatoid arthritis: a network meta-analysis publication-title: Adv Ther contributor: fullname: Tundia – volume: 44 start-page: 1112 issue: 8 year: 2017 end-page: 1117 ident: CR49 article-title: Importance of obtaining remission for work productivity and activity of patients with rheumatoid arthritis publication-title: J Rheumatol contributor: fullname: Takeuchi – volume: 31 start-page: 400 issue: 3 year: 2013 end-page: 408 ident: CR37 article-title: Cost-effectiveness simulation model of biologic strategies for treating to target rheumatoid arthritis in Germany publication-title: Clin Exp Rheumatol contributor: fullname: Zeidler – volume: 68 start-page: 1 issue: 1 year: 2016 end-page: 25 ident: CR7 article-title: 2015 American College of Rheumatology Guideline for the treatment of rheumatoid arthritis publication-title: Arthritis Care Res (Hoboken) contributor: fullname: Bridges – volume: 7 start-page: R1063 issue: 5 year: 2005 end-page: R1071 ident: CR11 article-title: DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment publication-title: Arthritis Res Ther contributor: fullname: Wyns – volume: 30 start-page: 384 issue: 3 year: 2015 end-page: 390 ident: CR34 article-title: Sleep quality in rheumatoid arthritis, and its association with disease activity in a Korean population publication-title: Korean J Intern Med contributor: fullname: Lee – volume: 9 start-page: 249 issue: 10 year: 2017 end-page: 262 ident: CR20 article-title: Sustained remission in rheumatoid arthritis: latest evidence and clinical considerations publication-title: Ther Adv Musculoskelet Dis contributor: fullname: Huizinga – volume: 12 start-page: 589 year: 2020 end-page: 594 ident: CR54 article-title: A cost per responder model for abatacept versus adalimumab among rheumatoid arthritis patients with seropositivity publication-title: Clinicoecon Outcomes Res contributor: fullname: Patel – ident: CR9 – volume: 29 start-page: 633 issue: 4 year: 2011 end-page: 641 ident: CR39 article-title: Assessing the cost-effectiveness of biologic agents for the management of moderate-to-severe rheumatoid arthritis in anti-TNF inadequate responders in Italy: a modelling approach publication-title: Clin Exp Rheumatol contributor: fullname: Salaffi – volume: 21 start-page: 1 issue: 71 year: 2017 end-page: 258 ident: CR18 article-title: The clinical effectiveness and cost-effectiveness of treat-to-target strategies in rheumatoid arthritis: a systematic review and cost-effectiveness analysis publication-title: Health Technol Assess contributor: fullname: Stevenson – volume: 26 start-page: 310 issue: 3 year: 2017 end-page: 319 ident: CR47 article-title: The clinical status and economic savings associated with remission among patients with rheumatoid arthritis: leveraging linked registry and claims data for synergistic insights publication-title: Pharmacoepidemiol Drug Saf contributor: fullname: Greenberg – volume: 70 start-page: 404 issue: 3 year: 2011 end-page: 413 ident: CR22 article-title: American College of Rheumatology/European League against Rheumatism provisional definition of remission in rheumatoid arthritis for clinical trials publication-title: Ann Rheum Dis contributor: fullname: Wells – volume: 28 start-page: 789 issue: 5 year: 2018 end-page: 799 ident: CR31 article-title: Residual symptoms and disease burden among patients with rheumatoid arthritis in remission or low disease activity: a systematic literature review publication-title: Mod Rheumatol contributor: fullname: Yoshida – volume: 65 start-page: 1707 issue: 10 year: 2013 end-page: 1712 ident: CR32 article-title: Patient perspectives on achieving treat-to-target goals: a critical examination of patient-reported outcomes publication-title: Arthritis Care Res (Hoboken) contributor: fullname: Reed – volume: 15 start-page: 33 issue: 1 year: 2019 end-page: 54 ident: CR16 article-title: Efficacy and safety of various anti-rheumatic treatments for patients with rheumatoid arthritis: a network meta-analysis publication-title: Arch Med Sci contributor: fullname: Zhou – volume: 37 start-page: 134 issue: 2 year: 2012 end-page: 142 ident: CR40 article-title: Finding Rheumatoid Arthritis Impact on Life (FRAIL Study): economic burden publication-title: Acta Reumatol Port contributor: fullname: Ferreira – ident: CR6 – volume: 73 start-page: 1677 issue: 9 year: 2014 end-page: 1682 ident: CR26 article-title: Early remission is associated with improved survival in patients with inflammatory polyarthritis: results from the Norfolk Arthritis Register publication-title: Ann Rheum Dis contributor: fullname: Verstappen – volume: 36 start-page: 499 issue: 3 year: 2017 end-page: 506 ident: CR50 article-title: Non-medical costs during the first year after diagnosis in two cohorts of patients with early rheumatoid arthritis, enrolled 10 years apart publication-title: Clin Rheumatol contributor: fullname: Hallert – volume: 59 start-page: 613 issue: 3 year: 2020 end-page: 621 ident: CR10 article-title: Defining remission in rheumatoid arthritis: does it matter to the patient? A comparison of multi-dimensional remission criteria and patient reported outcomes publication-title: Rheumatology (Oxford) contributor: fullname: Rabin – volume: 62 start-page: 108 issue: 1 year: 2010 end-page: 117 ident: CR15 article-title: Evidence for predictive validity of remission on long-term outcome in rheumatoid arthritis: a systematic review publication-title: Arthritis Care Res (Hoboken) contributor: fullname: Wells – volume: 76 start-page: 960 issue: 6 year: 2017 end-page: 977 ident: CR4 article-title: EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2016 update publication-title: Ann Rheum Dis contributor: fullname: Bijlsma – volume: 16 start-page: R56 issue: 1 year: 2014 ident: CR14 article-title: Remission in rheumatoid arthritis: benefit over low disease activity in patient-reported outcomes and costs publication-title: Arthritis Res Ther contributor: fullname: Aletaha – volume: 32 start-page: 1959 issue: 12 year: 2016 end-page: 1967 ident: CR48 article-title: Increased healthcare resource utilization in higher disease activity levels in initiators of TNF inhibitors among US rheumatoid arthritis patients publication-title: Curr Med Res Opin contributor: fullname: Mason – ident: CR23 – volume: 5 start-page: 40 year: 2018 ident: CR8 article-title: Common evaluations of disease activity in rheumatoid arthritis reach discordant classifications across different populations publication-title: Front Med (Lausanne) contributor: fullname: Gregorio – volume: 75 start-page: 3 issue: 1 year: 2016 end-page: 15 ident: CR3 article-title: Treating rheumatoid arthritis to target: 2014 update of the recommendations of an international task force publication-title: Ann Rheum Dis contributor: fullname: Burmester – volume: 75 start-page: 867 issue: 5 year: 2016 end-page: 873 ident: CR30 article-title: Disease-modifying antirheumatic drug-free sustained remission in rheumatoid arthritis: an increasingly achievable outcome with subsidence of disease symptoms publication-title: Ann Rheum Dis contributor: fullname: van der Helm-van Mil – volume: 3 start-page: 6 year: 2019 ident: CR25 article-title: Real world long-term impact of intensive treatment on disease activity, disability and health-related quality of life in rheumatoid arthritis publication-title: BMC Rheumatol contributor: fullname: Scott – volume: 14 start-page: 350 year: 2013 ident: CR17 article-title: Treating to the target of remission in early rheumatoid arthritis is cost-effective: results of the DREAM registry publication-title: BMC Musculoskelet Disord contributor: fullname: Kuper – volume: 38 start-page: 2727 issue: 10 year: 2019 end-page: 2736 ident: CR43 article-title: Long-term clinical, functional, and cost outcomes for early rheumatoid arthritis patients who did or did not achieve early remission in a real-world treat-to-target strategy publication-title: Clin Rheumatol contributor: fullname: van de Laar – volume: 12 start-page: R42 issue: 2 year: 2010 ident: CR2 article-title: Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA study publication-title: Arthritis Res Ther contributor: fullname: Pincus – volume: 36 start-page: 448 issue: 3 year: 2018 end-page: 454 ident: CR41 article-title: Cost-effectiveness of early treatment of ACPA-positive rheumatoid arthritis patients with abatacept publication-title: Clin Exp Rheumatol contributor: fullname: Baerwald – volume: 39 start-page: 1621 issue: 9 year: 2019 end-page: 1630 ident: CR53 article-title: Cost per response for abatacept versus adalimumab in patients with seropositive, erosive early rheumatoid arthritis in the US, Germany, Spain, and Canada publication-title: Rheumatol Int contributor: fullname: Bergman – volume: 13 start-page: 519 year: 2020 ident: CR52 article-title: JAK inhibitors in rheumatoid arthritis: an evidence-based review on the emerging clinical data publication-title: J Inflamm Res contributor: fullname: Conway – volume: 5 start-page: 185 year: 2018 ident: CR12 article-title: The utility and limitations of CRP, ESR and DAS28-CRP in appraising disease activity in rheumatoid arthritis publication-title: Front Med (Lausanne) contributor: fullname: Young – volume: 41 start-page: 1600 issue: 8 year: 2014 end-page: 1606 ident: CR46 article-title: Effect of remission definition on healthcare cost savings estimates for patients with rheumatoid arthritis treated with biologic therapies publication-title: J Rheumatol contributor: fullname: Ohinmaa – volume: 29 start-page: 1317 issue: 11 year: 2010 end-page: 1322 ident: CR35 article-title: Paid work is associated with improved health-related quality of life in patients with rheumatoid arthritis publication-title: Clin Rheumatol contributor: fullname: Steinsbekk – volume: 72 start-page: 1664 issue: 10 year: 2013 end-page: 1668 ident: CR45 article-title: Healthcare service utilisation costs are reduced when rheumatoid arthritis patients achieve sustained remission publication-title: Ann Rheum Dis contributor: fullname: Ohinmaa – volume: 29 start-page: 633 issue: 4 year: 2011 ident: 1946_CR39 publication-title: Clin Exp Rheumatol contributor: fullname: MA Cimmino – volume: 59 start-page: 613 issue: 3 year: 2020 ident: 1946_CR10 publication-title: Rheumatology (Oxford) contributor: fullname: HL Gul – volume: 38 start-page: 2727 issue: 10 year: 2019 ident: 1946_CR43 publication-title: Clin Rheumatol doi: 10.1007/s10067-019-04600-7 contributor: fullname: PM Ten Klooster – volume: 67 start-page: 1474 issue: 6 year: 2015 ident: 1946_CR51 publication-title: Arthritis Rheumatol doi: 10.1002/art.39079 contributor: fullname: J Yazdany – volume: 21 start-page: 1 issue: 71 year: 2017 ident: 1946_CR18 publication-title: Health Technol Assess doi: 10.3310/hta21710 contributor: fullname: A Wailoo – volume: 38 start-page: 439 issue: 3 year: 2011 ident: 1946_CR38 publication-title: J Rheumatol doi: 10.3899/jrheum.100589 contributor: fullname: A Beresniak – volume: 31 start-page: 400 issue: 3 year: 2013 ident: 1946_CR37 publication-title: Clin Exp Rheumatol contributor: fullname: A Beresniak – ident: 1946_CR23 – volume: 74 start-page: 415 issue: 2 year: 2015 ident: 1946_CR27 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2013-204021 contributor: fullname: J Listing – volume: 41 start-page: 1600 issue: 8 year: 2014 ident: 1946_CR46 publication-title: J Rheumatol doi: 10.3899/jrheum.131449 contributor: fullname: C Barnabe – volume: 2011 year: 2011 ident: 1946_CR36 publication-title: Int J Inflamm. doi: 10.4061/2011/727634 contributor: fullname: A Beresniak – volume: 68 start-page: 308 issue: 3 year: 2016 ident: 1946_CR24 publication-title: Arthritis Care Res (Hoboken) doi: 10.1002/acr.22678 contributor: fullname: E Alemao – volume: 15 start-page: 33 issue: 1 year: 2019 ident: 1946_CR16 publication-title: Arch Med Sci doi: 10.5114/aoms.2018.73714 contributor: fullname: K Ma – volume: 39 start-page: 1621 issue: 9 year: 2019 ident: 1946_CR53 publication-title: Rheumatol Int doi: 10.1007/s00296-019-04352-2 contributor: fullname: J Foo – volume: 75 start-page: 3 issue: 1 year: 2016 ident: 1946_CR3 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2015-207524 contributor: fullname: JS Smolen – volume: 73 start-page: 1677 issue: 9 year: 2014 ident: 1946_CR26 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2013-203339 contributor: fullname: CA Scire – volume: 26 start-page: 310 issue: 3 year: 2017 ident: 1946_CR47 publication-title: Pharmacoepidemiol Drug Saf doi: 10.1002/pds.4126 contributor: fullname: JR Curtis – volume: 37 start-page: 2356 issue: 5 year: 2020 ident: 1946_CR5 publication-title: Adv Ther doi: 10.1007/s12325-020-01303-3 contributor: fullname: J Pope – volume: 50 start-page: 401 issue: 2 year: 2011 ident: 1946_CR33 publication-title: Rheumatology (Oxford) doi: 10.1093/rheumatology/keq327 contributor: fullname: J Kekow – volume: 76 start-page: 960 issue: 6 year: 2017 ident: 1946_CR4 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2016-210715 contributor: fullname: JS Smolen – volume: 28 start-page: 789 issue: 5 year: 2018 ident: 1946_CR31 publication-title: Mod Rheumatol doi: 10.1080/14397595.2017.1416940 contributor: fullname: M Ishida – volume: 30 start-page: 384 issue: 3 year: 2015 ident: 1946_CR34 publication-title: Korean J Intern Med doi: 10.3904/kjim.2015.30.3.384 contributor: fullname: CN Son – volume: 13 start-page: 519 year: 2020 ident: 1946_CR52 publication-title: J Inflamm Res doi: 10.2147/JIR.S219586 contributor: fullname: R Harrington – volume: 5 start-page: 40 year: 2018 ident: 1946_CR8 publication-title: Front Med (Lausanne) doi: 10.3389/fmed.2018.00040 contributor: fullname: H Canhao – volume: 37 start-page: 134 issue: 2 year: 2012 ident: 1946_CR40 publication-title: Acta Reumatol Port contributor: fullname: LC Miranda – volume: 74 start-page: 1676 issue: 9 year: 2015 ident: 1946_CR29 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2013-204906 contributor: fullname: A Ruyssen-Witrand – volume: 320 start-page: 1360 issue: 13 year: 2018 ident: 1946_CR1 publication-title: JAMA doi: 10.1001/jama.2018.13103 contributor: fullname: D Aletaha – volume: 62 start-page: 108 issue: 1 year: 2010 ident: 1946_CR15 publication-title: Arthritis Care Res (Hoboken) doi: 10.1002/acr.20021 contributor: fullname: LH van Tuyl – volume: 32 start-page: 1959 issue: 12 year: 2016 ident: 1946_CR48 publication-title: Curr Med Res Opin doi: 10.1080/03007995.2016.1222515 contributor: fullname: N Boytsov – ident: 1946_CR9 doi: 10.1016/j.rdc.2009.10.001 – volume: 12 start-page: 589 year: 2020 ident: 1946_CR54 publication-title: Clinicoecon Outcomes Res doi: 10.2147/CEOR.S263903 contributor: fullname: SH Park – volume: 7 start-page: R1063 issue: 5 year: 2005 ident: 1946_CR11 publication-title: Arthritis Res Ther doi: 10.1186/ar1787 contributor: fullname: B Vander Cruyssen – volume: 37 start-page: 1111 issue: 7 year: 2017 ident: 1946_CR55 publication-title: Rheumatol Int doi: 10.1007/s00296-017-3739-9 contributor: fullname: L Weijers – volume: 17 start-page: 181 year: 2015 ident: 1946_CR21 publication-title: Arthritis Res Ther doi: 10.1186/s13075-015-0707-1 contributor: fullname: G Nagy – volume: 75 start-page: 867 issue: 5 year: 2016 ident: 1946_CR30 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2014-207080 contributor: fullname: S Ajeganova – volume: 6 start-page: 38 year: 2012 ident: 1946_CR42 publication-title: Open Rheumatol J doi: 10.2174/1874312901206010038 contributor: fullname: K Puolakka – volume: 72 start-page: 1664 issue: 10 year: 2013 ident: 1946_CR45 publication-title: Ann Rheum Dis doi: 10.1136/annrheumdis-2012-201918 contributor: fullname: C Barnabe – volume: 36 start-page: 499 issue: 3 year: 2017 ident: 1946_CR50 publication-title: Clin Rheumatol doi: 10.1007/s10067-016-3470-z contributor: fullname: M Husberg – volume: 364 start-page: 263 issue: 9430 year: 2004 ident: 1946_CR19 publication-title: Lancet doi: 10.1016/S0140-6736(04)16676-2 contributor: fullname: C Grigor – volume: 14 start-page: 350 year: 2013 ident: 1946_CR17 publication-title: BMC Musculoskelet Disord doi: 10.1186/1471-2474-14-350 contributor: fullname: M Vermeer – volume: 5 start-page: 185 year: 2018 ident: 1946_CR12 publication-title: Front Med (Lausanne) doi: 10.3389/fmed.2018.00185 contributor: fullname: CK Orr – ident: 1946_CR6 – volume: 70 start-page: 1815 issue: 10 year: 2011 ident: 1946_CR13 publication-title: Ann Rheum Dis doi: 10.1136/ard.2010.149260 contributor: fullname: NB Klarenbeek – volume: 29 start-page: 1317 issue: 11 year: 2010 ident: 1946_CR35 publication-title: Clin Rheumatol doi: 10.1007/s10067-010-1534-z contributor: fullname: K Gronning – volume: 70 start-page: 404 issue: 3 year: 2011 ident: 1946_CR22 publication-title: Ann Rheum Dis doi: 10.1136/ard.2011.149765 contributor: fullname: DT Felson – volume: 12 start-page: R42 issue: 2 year: 2010 ident: 1946_CR2 publication-title: Arthritis Res Ther doi: 10.1186/ar2951 contributor: fullname: T Sokka – volume: 16 start-page: R56 issue: 1 year: 2014 ident: 1946_CR14 publication-title: Arthritis Res Ther doi: 10.1186/ar4491 contributor: fullname: H Radner – volume: 9 start-page: 249 issue: 10 year: 2017 ident: 1946_CR20 publication-title: Ther Adv Musculoskelet Dis doi: 10.1177/1759720X17720366 contributor: fullname: S Ajeganova – volume: 65 start-page: 1707 issue: 10 year: 2013 ident: 1946_CR32 publication-title: Arthritis Care Res (Hoboken) doi: 10.1002/acr.22048 contributor: fullname: JR Curtis – volume: 44 start-page: 1112 issue: 8 year: 2017 ident: 1946_CR49 publication-title: J Rheumatol doi: 10.3899/jrheum.161404 contributor: fullname: D Kim – volume: 36 start-page: 448 issue: 3 year: 2018 ident: 1946_CR41 publication-title: Clin Exp Rheumatol contributor: fullname: AS Neubauer – volume: 3 start-page: 6 year: 2019 ident: 1946_CR25 publication-title: BMC Rheumatol doi: 10.1186/s41927-019-0054-y contributor: fullname: NJ Gullick – volume: 17 start-page: 203 year: 2015 ident: 1946_CR28 publication-title: Arthritis Res Ther doi: 10.1186/s13075-015-0719-x contributor: fullname: H Radner – volume: 68 start-page: 1 issue: 1 year: 2016 ident: 1946_CR7 publication-title: Arthritis Care Res (Hoboken) doi: 10.1002/acr.22783 contributor: fullname: JA Singh – volume: 50 start-page: 1259 issue: 7 year: 2011 ident: 1946_CR44 publication-title: Rheumatology (Oxford) doi: 10.1093/rheumatology/keq444 contributor: fullname: E Hallert |
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Snippet | The treat-to-target strategy, which defines clinical remission as the primary therapeutic goal for rheumatoid arthritis (RA), is a widely recommended treatment... |
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SubjectTerms | Antirheumatic Agents Arthritis, Rheumatoid - drug therapy Cardiology Cost-Benefit Analysis Efficiency Endocrinology Health Care Costs Humans Internal Medicine Medicine Medicine & Public Health Oncology Patient Acceptance of Health Care Pharmacology/Toxicology Quality of Life Review Rheumatology |
Title | Value of Remission in Patients with Rheumatoid Arthritis: A Targeted Review |
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