Early expansion of activated adaptive but also exhausted NK cells during acute severe SARS-CoV-2 infection

• Published in: Frontiers in cellular and infection microbiology Vol. 13; p. 1266790
• Main Authors: Claus, Maren, Pieris, Naomi, Urlaub, Doris, Bröde, Peter, Schaaf, Bernhard, Durak, Deniz, Renken, Frank, Watzl, Carsten
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 30.08.2023
• Subjects: Cellular and Infection Microbiology; COVID-19; exhaustion; immunophenotyping; natural killer (NK) cell; SARS-CoV-2 infection

The analysis of immunological parameters during the course of a SARS-CoV-2 infection is of great importance, both to identify diagnostic markers for the risk of a severe course of COVID-19, and to better understand the role of the immune system during the infection. By using multicolor flow cytometr...