Lower expression of adiponectin mRNA in visceral adipose tissue in lean and obese subjects

• Published in: Molecular and cellular endocrinology Vol. 219; no. 1; pp. 9 - 15
• Main Authors: Lihn, Aina S, Bruun, Jens M, He, Gengsheng, Pedersen, Steen B, Jensen, Peter F, Richelsen, Bjørn
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier Ireland Ltd 30.04.2004
• Subjects: (Human) subcutaneous adipose tissue; (Human) visceral adipose tissue; Adiponectin; Adipose Tissue - metabolism; Adult; Female; Gene expression; Gene Expression - drug effects; Humans; IL-1β; Intercellular Signaling Peptides and Proteins - biosynthesis; Intercellular Signaling Peptides and Proteins - genetics; Interleukin-1 - pharmacology; Middle Aged; Obesity; Obesity - genetics; Obesity - metabolism; RNA, Messenger - metabolism; Obesity; (Human) visceral adipose tissue; (Human) subcutaneous adipose tissue; IL-1β; Gene expression; Adiponectin

Adiponectin is an adipocyte-specific protein suggested to play a role in mediating the metabolic effects of obesity. In the present study, we investigated adiponectin mRNA levels in both visceral and subcutaneous abdominal adipose tissue (AT) from lean and obese subjects. Investigations on both “fre...