Stereotactic body radiotherapy for primary renal cell carcinoma: a systematic review and practice guideline from the International Society of Stereotactic Radiosurgery (ISRS)

• Published in: The lancet oncology Vol. 25; no. 1; pp. e18 - e28
• Main Authors: Siva, Shankar, Louie, Alexander V, Kotecha, Rupesh, Barber, Melissa N, Ali, Muhammad, Zhang, Zhenwei, Guckenberger, Matthias, Kim, Mi-Sook, Scorsetti, Marta, Tree, Alison C, Slotman, Ben J, Sahgal, Arjun, Lo, Simon S
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.01.2024; Elsevier Limited
• Subjects: Ablation; Biopsy; Cancer therapies; Carcinoma, Renal Cell - radiotherapy; Carcinoma, Renal Cell - surgery; Clinical practice guidelines; Clinical trials; Dosimetry; Hematology, Oncology, and Palliative Medicine; Humans; Kidney; Kidney cancer; Kidney Neoplasms - radiotherapy; Kidney Neoplasms - surgery; Oncology; Patients; Prospective Studies; Radiation therapy; Radiosurgery; Radiosurgery - adverse effects; Renal cell carcinoma; Systematic review; Tumors
• ISSN: 1470-2045; 1474-5488; 1474-5488
• DOI: 10.1016/S1470-2045(23)00513-2

Surgery is the standard of care for patients with primary renal cell carcinoma. Stereotactic body radiotherapy (SBRT) is a novel alternative for patients who are medically inoperable, technically high risk, or who decline surgery. Evidence for using SBRT in the primary renal cell carcinoma setting i...