Heparin-induced thrombocytopenia associated with low-molecular-weight heparin: clinical feature analysis of cases and pharmacovigilance assessment of the FAERS database

• Published in: Frontiers in pharmacology Vol. 14; p. 1247253
• Main Authors: Liu, Leping, Zheng, Hong, Chen, Shanshan, Wang, Shengfeng, Yang, Minghua
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 20.09.2023
• Subjects: characteristics; heparin-induced thrombocytopenia; low-molecular-weight heparin; Pharmacology; pharmacovigilance; treatments

Background: Unfractionated heparin (UFH) and low-molecular-weight heparin (LMWH) are commonly used anticoagulants for the management of arterial and venous thromboses. However, it is crucial to be aware that LMWH can, in rare cases, lead to a dangerous complication known as heparin-induced thrombocy...