Analysis of factor VIII mediated suppression of lentiviral vector titres - Radcliffe, P A; Sion, C J M; Wilkes, F J; Custard, E J; Beard, G L; Kingsman, S M; Mitrophanous, K A (Gene therapy, 2008)
Keywords: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Applied cell therapy and gene therapy; Biological and medical sciences; Biomedical and Life Sciences; Biomedicine; Biotechnology; Cell Biology; Cell Line; Coagulation factors; Codon; Factor VIII - genetics; Fundamental and applied biological sciences. Psychology; Gene Expression; Gene Therapy; Genetic Therapy; Genetic Vectors; Genomes; Health. Pharmaceutical industry; Hemophilia; Hemophilia A - therapy; Human Genetics; Humans; Immune response; Industrial applications and implications. Economical aspects; Infectious Anemia Virus, Equine - genetics; Lentivirus; Medical sciences; Nanotechnology; original-article; Polymerase Chain Reaction; Producer cells; Promoter Regions, Genetic; RNA-directed DNA polymerase; Stomatitis; Transfusions. Complications. Transfusion reactions. Cell and gene therapy; Vesicular stomatitis virus; Viruses; haemophilia; codon optimization; pseudotyping; lentiviral vectors; factor VIII; Suppression; Factor VIII; Retroviridae; Hemopathy; Lentivirus; Hemophilia A; Optimization; Genetic disease; Virus; Codon; Gene therapy; Vector; Coagulopathy