Advances in immunotyping of colorectal cancer

• Published in: Frontiers in immunology Vol. 14; p. 1259461
• Main Authors: Wu, Yinhang, Zhuang, Jing, Qu, Zhanbo, Yang, Xi, Han, Shuwen
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 09.10.2023
• Subjects: colorectal cancer; colorectal cancer subtypes; immune subtype; Immunology; immunotherapy; tumor immune microenvironment

Immunotherapy has transformed treatment for various types of malignancy. However, the benefit of immunotherapy is limited to a minority of patients with mismatch-repair-deficient (dMMR) and microsatellite instability-high (MSI-H) (dMMR-MSI-H) colorectal cancer (CRC). Understanding the complexity and...