Topographical analysis of the structural, biochemical and dynamic biomechanical properties of cartilage in an ovine model of osteoarthritis

• Published in: Osteoarthritis and cartilage Vol. 11; no. 1; pp. 65 - 77
• Main Authors: Appleyard, R.C., Burkhardt, D., Ghosh, P., Read, R., Cake, M., Swain, M.V., Murrell, G.A.C.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.01.2003
• Subjects: Animals; Articular cartilage, Meniscectomy, Biomechanics, Biochemistry; Biomechanical Phenomena; Cartilage, Articular - chemistry; Collagen - metabolism; Glycosaminoglycans - metabolism; Hindlimb; Menisci, Tibial; Osteoarthritis, Knee - metabolism; Osteoarthritis, Knee - physiopathology; Proteoglycans - metabolism; Sheep; Articular cartilage, Meniscectomy, Biomechanics, Biochemistry

Objective The relationship between the topographical variations in the structural, biochemical and dynamic biomechanical properties of articular cartilage (AC) before and 6 months after meniscectomy has not been previously reported but is clearly relevant to our understanding of the role of mechanic...