Neurovascular Complications of Iatrogenic Fusarium solani Meningitis

• Published in: The New England journal of medicine Vol. 390; no. 6; pp. 522 - 529
• Main Authors: Strong, Nora, Meeks, Grant, Sheth, Sunil A., McCullough, Louise, Villalba, Julian A., Tan, Chunfeng, Barreto, Andrew, Wanger, Audrey, McDonald, Michelle, Kan, Peter, Shaltoni, Hashem, Campo Maldonado, Jose, Parada, Victoria, Hassan, Ameer E., Reagan-Steiner, Sarah, Chiller, Tom, Gold, Jeremy A.W., Smith, Dallas J., Ostrosky-Zeichner, Luis
• Format: Journal Article
• Language: English
• Published: United States Massachusetts Medical Society 08.02.2024
• Series: Brief Report
• Subjects: Analgesia, Epidural - adverse effects; Anesthesia; Aneurysms; Antifungal agents; Antifungal Agents - therapeutic use; Autopsies; Brain stem; Contamination; Disease Outbreaks - statistics & numerical data; Drug Resistance, Fungal; Encephalitis; Epidemics; Epidural; Fungal Infections; Fusariosis - epidemiology; Fusariosis - etiology; Fusarium - isolation & purification; Global Health; Hemorrhage; Hospital systems; Hospitals; Human subjects; Humans; Iatrogenic Disease - epidemiology; Immunocompetence; Infections; Infectious Disease; Infectious Disease General; Inflammation; Internationality; Meningitis; Meningitis, Fungal - epidemiology; Meningitis, Fungal - etiology; Mexico - epidemiology; Neurology; Neurosurgery; Neurosurgery General; Outbreaks; Pain; Pathogens; Pathology; Patients; Surgery; Surgery General; Mexico; United States > US; Texas

A multinational outbreak of nosocomial fusarium meningitis occurred among immunocompetent patients who had undergone surgery with epidural anesthesia in Mexico. The pathogen involved had a high predilection for the brain stem and vertebrobasilar arterial system and was associated with high mortality...