Effect of acute alcohol ingestion on short-term heart rate fluctuations

• Published in: Journal of studies on alcohol Vol. 53; no. 1; p. 86
• Main Authors: Gonzalez Gonzalez, J, Mendez Llorens, A, Mendez Novoa, A, Cordero Valeriano, J J
• Format: Journal Article
• Language: English
• Published: United States 01.01.1992
• Subjects: Adult; Alcohol Drinking - physiopathology; Alcoholic Intoxication - physiopathology; Dose-Response Relationship, Drug; Electrocardiography - drug effects; Electrocardiography - instrumentation; Ethanol - pharmacokinetics; Heart Rate - drug effects; Heart Rate - physiology; Humans; Male; Microcomputers; Parasympathetic Nervous System - drug effects; Parasympathetic Nervous System - physiopathology; Signal Processing, Computer-Assisted - instrumentation; Sympathetic Nervous System - drug effects; Sympathetic Nervous System - physiopathology
• DOI: 10.15288/jsa.1992.53.86
• ISSN: 0096-882X

Acute ingestion of a low dose of alcohol (0.3 g/Kg) in a group of 18 healthy volunteers does not alter RR mean nor RR variance, producing only a slight decrease in the heart rate variability (HRV) measured by the mean momentary arrhythmia. However, power spectral of the HRV signal shows appreciable changes in the magnitude of the short-term RR fluctuations. Low frequency RR oscillations (0.02-0.06 Hz) increase in power during the 20-45 min. period after alcohol intake, while middle (0.08-0.15 Hz) frequency oscillations decrease in power during the 20-60 min. period and higher (0.20-0.35 Hz) frequency oscillations decrease in power during the 5-60 min. period after intake. The most drastic changes were observed in the middle frequency oscillations during the 20-30 min. period after intake while higher frequency oscillations seem to be less affected by the alcohol ingestion.