Role of Quantitative CT in Predicting Hypoxemia and Complications After Lung Lobectomy for Cancer, With Special Reference to Area of Emphysema

• Published in: Chest Vol. 128; no. 5; pp. 3500 - 3506
• Main Authors: Ueda, Kazuhiro, Kaneda, Yoshikazu, Sudoh, Manabu, Mitsutaka, Jinbo, Tanaka, Nobuyuki, Suga, Kazuyoshi, Hamano, Kimikazu
• Format: Journal Article
• Language: English
• Published: Northbrook, IL Elsevier Inc 01.11.2005; American College of Chest Physicians
• Subjects: 3D = three dimensional; Aged; Biological and medical sciences; Cancer; Cardiology. Vascular system; complication; CPC = cardiopulmonary complication; Emphysema; Female; HU = Hounsfield units; Humans; hypoxemia; Hypoxia - etiology; LAA = extent of low-attenuation area; Logistic Models; low attenuation area; Lung diseases; Lung Neoplasms - surgery; Male; Medical sciences; Middle Aged; Oxygen - blood; Oxygen saturation; Patients; Pneumology; Pneumonectomy - adverse effects; postSao2= postoperative arterial oxygen saturation; ppoFEV1= predicted postoperative FEV1; ppoSao2= predicted postoperative arterial oxygen saturation; preSao2= preoperative arterial oxygen saturation; Proportional Hazards Models; Prospective Studies; Pulmonary Emphysema - diagnostic imaging; Pulmonary Emphysema - etiology; pulmonary resection; quantitative CT; Respiratory system : syndromes and miscellaneous diseases; Sao2= arterial oxygen saturation; Smoking; Spirometry; Thoracic surgery; Tomography, X-Ray Computed - methods; Tumors of the respiratory system and mediastinum; Variables; VC = vital capacity; hypoxemia; complication; preSao2= preoperative arterial oxygen saturation; pulmonary resection; postSao2= postoperative arterial oxygen saturation; quantitative CT; LAA = extent of low-attenuation area; CPC = cardiopulmonary complication; spirometry; HU = Hounsfield units; low attenuation area; ppoSao2= predicted postoperative arterial oxygen saturation; ppoFEV1= predicted postoperative FEV1; VC = vital capacity; 3D = three dimensional; Sao2= arterial oxygen saturation; Spirometry; Lung cancer; Cardiovascular disease; Lung function; Hypoxemia; Surgery; Bronchus disease; Attenuation; Complication; Obstructive pulmonary disease; Quantitative analysis; Lung disease; Oxygen; Radiodiagnosis; Respiratory disease; Reference; Exploration; Surgical resection; Area; Treatment; Low; Medical imagery; Computerized axial tomography; Emphysema; Lobectomy

Study objectives: To determine the ability of quantitative CT, with special reference to area of emphysema, to predict early postoperative oxygenation capacity and outcome after lung lobectomy for cancer. Methods: Sixty-two consecutive patients scheduled to undergo lung lobectomy for cancer were enr...