Segregation analysis of body mass index in a large sample selected for obesity: the Swedish Obese Subjects study

• Published in: Obesity research Vol. 7; no. 3; pp. 246 - 255
• Main Authors: Rice, T, Sjostrom, C.D, Perusse, L, Rao, D.C, Sjostrom, L, Bouchard, C
• Format: Journal Article
• Language: English
• Published: United States 01.05.1999
• Subjects: Adult; age differences; Age Factors; Body Height - genetics; Body Mass Index; body measurements; Body Weight - genetics; Computer Simulation; Female; gender differences; genetic techniques and protocols; genotype; genotype-environment interaction; Humans; indexes; Likelihood Functions; major genes; Male; Middle Aged; Models, Biological; obesity; Obesity - genetics; Pedigree; Regression Analysis; segregation; Sex Factors; Surveys and Questionnaires; Sweden; Sweden

To investigate a major gene hypothesis for body mass index (BMI) in a large sample of probands (n = 2580, ages 37-57 years) who were selected for obesity (BMI> or =34 kg/m2 for males and > or =38 kg/m2 for females), along with their spouses and first-degree relatives (n = 11,204 family members...