Humoral immunity in natural infection by tick-borne encephalitis virus

• Published in: Journal of medical virology Vol. 81; no. 4; pp. 665 - 671
• Main Authors: Venturi, Giulietta, Martelli, Paola, Mazzolini, Elena, Fiorentini, Cristiano, Benedetti, Eleonora, Todone, Daniele, Villalta, Danilo, Fortuna, Claudia, Marchi, Antonella, Minelli, Giada, Ciufolini, Maria Grazia
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 01.04.2009; Wiley
• Subjects: Action of physical and chemical agents; Adolescent; Adult; Aged; Aged, 80 and over; Animals; Animals, Wild - virology; Antibodies, Viral - blood; Antibody Formation; Biological and medical sciences; Child; Deer - virology; diagnosis; ELISA; Encephalitis Viruses, Tick-Borne - immunology; Encephalitis, Tick-Borne - diagnosis; Encephalitis, Tick-Borne - epidemiology; Encephalitis, Tick-Borne - immunology; Encephalitis, Tick-Borne - virology; Enzyme-Linked Immunosorbent Assay; Female; flavivirus; Fundamental and applied biological sciences. Psychology; Hemagglutination Inhibition Tests; hemagglutination-inhibition test; Human viral diseases; Humans; Immunoglobulin G - blood; Immunoglobulin M - blood; Infectious diseases; Italy - epidemiology; Male; Medical sciences; Microbiology; Middle Aged; Miscellaneous; neutralization test; Neutralization Tests; Ruminantia; Rupicapra - virology; Tick-borne encephalitis virus; Viral diseases; Viral Plaque Assay; Virology; Young Adult; Italy; Natural immunity; Enzyme immunoassay; Flavivirus; hemagglutination-inhibition test; Tick borne encephalitis group virus; Virus; Infection; Hemagglutination; Neutralization test; Diagnosis; Flaviviridae; ELISA assay; Tick borne encephalitis virus; Humoral immunity; ELISA

Tick-borne encephalitis (TBE) virus is one of the most important flaviviruses associated with neurological disease in Europe. Cross-reactive antibodies elicited by different flaviviruses can make difficult the interpretation of ELISA and hemagglutination-inhibition (HI) tests for the diagnosis of TB...