Narciclasine attenuates LPS-induced acute lung injury in neonatal rats through suppressing inflammation and oxidative stress

• Published in: Bioengineered Vol. 11; no. 1; pp. 801 - 810
• Main Authors: Duan, Qingning, Jia, Yin, Qin, Yan, Jin, Yingji, Hu, Haozhong, Chen, Jiebin
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 01.01.2020
• Subjects: acute lung injury; inflammation; Narciclasine; oxidative stress; Research Paper; TLR4/NF-κB/Cox2

Acute lung injury (ALI) is a life-threatening disorder related to serious pulmonary inflammation. Narciclasine exhibits strong anti-inflammation activity and attenuates the reactive oxygen species (ROS) production. The present study aims to investigate the underlying mechanism related to the effect...