Insulin-binding protein-5 down-regulates the balance of Th17/Treg

• Published in: Frontiers in immunology Vol. 13; p. 1019248
• Main Authors: Zhu, Mengyuan, Han, Han, Hu, Lei, Cao, Yu, Fan, Zhipeng
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 01.11.2022
• Subjects: immune homeostasis; Immunology; inflammation response; inflammatory diseases; insulin-binding protein-5; Th17

The inflammatory response plays critical important role in tissue hemostasis. Our previous study showed insulin-binding protein-5 (IGFBP5) could enhance the regeneration of tissue defect under inflammation condition, but the function of IGFBP5 in controlling inflammation and regulating immune respon...