Refined Multiscale Entropy: Application to 24-h Holter Recordings of Heart Period Variability in Healthy and Aortic Stenosis Subjects

• Published in: IEEE transactions on biomedical engineering Vol. 56; no. 9; pp. 2202 - 2213
• Main Authors: Valencia, Jose Fernando, Porta, Alberto, Vallverdu, Montserrat, Claria, Francesc, Baranowski, Rafal, Orlowska-Baranowska, Ewa, Caminal, Pere
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.09.2009; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Aortic stenosis (AS); Aortic Valve Stenosis - physiopathology; Biomedical engineering; Biomedical informatics; Circadian Rhythm; complexity; Control systems; Electrocardiography, Ambulatory - methods; Entropy; Government; Heart; Heart Rate - physiology; Heart rate variability; heart rate variability (HRV); Humans; Information analysis; Large-scale systems; Models, Cardiovascular; Models, Statistical; multiscale entropy (MSE); Orthopedic surgery; Pattern Recognition, Automated - methods; refined multiscale entropy (RMSE); Statistics, Nonparametric; Time series analysis

Multiscale entropy (MSE) was proposed to characterize complexity as a function of the time-scale factor tau. Despite its broad use, this technique suffers from two limitations: (1) the artificial MSE reduction due to the coarse graining procedure and (2) the introduction of spurious MSE oscillations...