Universal screening for hyperglycemia in early pregnancy and the risk of adverse pregnancy outcomes

• Published in: BMC pregnancy and childbirth Vol. 25; no. 1; pp. 203 - 10
• Main Authors: Shen, Lixia, Zhang, Shaofeng, Wen, Jiying, Liu, Jia, Lin, Xiaohong, Zhu, Caixia, Cai, Shiqin, Xie, Lepei, Wang, Zilian, Chen, Haitian
• Format: Journal Article
• Language: English
• Published: England BioMed Central 25.02.2025; BMC
• Subjects: Adult; Antenatal screening; Asian people; Blood Glucose - analysis; Cesarean section; China - epidemiology; Diabetes, Gestational - blood; Diabetes, Gestational - diagnosis; Diabetes, Gestational - epidemiology; Female; Fetal Macrosomia - epidemiology; Gestational age; Gestational diabetes; Glucose; Glycated Hemoglobin - analysis; HbA1c; Humans; Hyperglycemia; Hyperglycemia - blood; Hyperglycemia - complications; Hyperglycemia - diagnosis; Hyperglycemia - epidemiology; Hypertension; Mass Screening - methods; Medical diagnosis; Miscarriage; Outcome; Population; Postpartum period; Prediabetes; Preeclampsia; Pregnancy; Pregnancy Complications - diagnosis; Pregnancy Complications - epidemiology; Pregnancy Outcome - epidemiology; Pregnancy Trimester, First - blood; Premature birth; Premature Birth - epidemiology; Prenatal care; Retrospective Studies; Risk Factors; Stillbirth; Womens health; China; Antenatal screening; Gestational diabetes; Prediabetes; HbA1c; Outcome

This study aimed to evaluate the screening outcomes in women with hyperglycemia in early pregnancy (fasting plasma glucose [FPG] 5.1-6.9 mmol/L and/or HbA1c 39-46 mmol/mol before 20 weeks of gestation). This multicenter retrospective cohort study was conducted in China between 2016 and 2022. In our...