Diastolic Dysfunction of the Cardiac Allograft and Maximal Exercise Capacity

• Published in: The Journal of heart and lung transplantation Vol. 28; no. 5; pp. 434 - 439
• Main Authors: Roten, L., MD, Schmid, J.-P., MD, Merz, F., MD, Carrel, T., MD, Zwahlen, M., PhD, Walpoth, N., MD, Mohacsi, P., MD, Hullin, R., MD
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Inc 01.05.2009; Elsevier
• Subjects: Adult; Aged; Biological and medical sciences; Cardiology. Vascular system; Diastole - physiology; Echocardiography, Doppler; Exercise Test; Female; Heart Failure - diagnosis; Heart Failure - physiopathology; Heart Transplantation - physiology; Humans; Male; Medical sciences; Middle Aged; Oxygen - blood; Postoperative Complications - diagnosis; Postoperative Complications - physiopathology; Predictive Value of Tests; Prognosis; Surgery; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Surgery of the heart; Systole - physiology; Ventricular Dysfunction, Left - diagnosis; Ventricular Dysfunction, Left - physiopathology; Heart; Physical exercise; Transplantation; Homotransplantation; Phlebology; Treatment; Capacity; Dysfunction; Surgery; Graft; Exercise tolerance test; Circulatory system; Cardiology

Background Peak oxygen uptake (peak V o2 ) is an established integrative measurement of maximal exercise capacity in cardiovascular disease. After heart transplantation (HTx) peak V o2 remains reduced despite normal systolic left ventricular function, which highlights the relevance of diastolic func...