Repeatability of Linear and Nonlinear Elastic Modulus Maps From Repeat Scans in the Breast

• Published in: IEEE transactions on medical imaging Vol. 40; no. 2; pp. 748 - 757
• Main Authors: Gendin, Daniel I., Nayak, Rohit, Wang, Yuqi, Bayat, Mahdi, Fazzio, Robert T., Oberai, Assad A., Hall, Timothy J., Barbone, Paul E., Alizad, Azra, Fatemi, Mostafa
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.02.2021; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Algorithms; Breast; Breast - diagnostic imaging; Breast cancer; Compression; Cross correlation; Data acquisition; Elastic deformation; Elastic Modulus; elastic nonlinearity; Elasticity; Elasticity Imaging Techniques; Elastography; Evaluation; Humans; Image acquisition; Imaging; inverse problem; Inverse problems; Iterative methods; Lesions; Mechanical properties; Modulus of elasticity; Nonlinear systems; Nonlinearity; Optimization; Parameter modification; Phantoms, Imaging; quantitative; Reproducibility; Soft tissues; Strain; Tissues; Tracking; Ultrasonic imaging

Compression elastography allows the precise measurement of large deformations of soft tissue in vivo. From an image sequence showing tissue undergoing large deformation, an inverse problem for both the linear and nonlinear elastic moduli distributions can be solved. As part of a larger clinical stud...