Neuronal dysfunction and disconnection of cortical hubs in non-demented subjects with elevated amyloid burden - Drzezga, Alexander; Becker, J. Alex; Van Dijk, Koene R. A.; Sreenivasan, Aishwarya; Talukdar, Tanveer; Sullivan, Caroline; Schultz, Aaron P.; Sepulcre, Jorge; Putcha, Deepti; Greve, Doug; Johnson, Keith A.; Sperling, Reisa A. (Brain (London, England : 1878), 2011)
Keywords: Aged; Aged, 80 and over; Alzheimer Disease - complications; Alzheimer Disease - diagnostic imaging; Alzheimer Disease - pathology; Amyloid - metabolism; Benzothiazoles; Biological and medical sciences; Brain Mapping; Cerebral Cortex - blood supply; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - metabolism; Cerebral Cortex - pathology; Cognition Disorders - diagnostic imaging; Cognition Disorders - etiology; Cognition Disorders - pathology; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases; Female; Fluorodeoxyglucose F18; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging - methods; Male; Medical sciences; Middle Aged; Neurology; Original; Oxygen - blood; Positron-Emission Tomography - methods; Statistics as Topic; Human; Nervous system diseases; magnetic resonance imaging; Cognitive disorder; Metabolism; Nuclear magnetic resonance imaging; functional connectivity; Dysfunction; cortical hubs; Amyloid; mild cognitive impairment; Positron emission tomography; Emission tomography