Dynamic effects of cholinergic blockade upon cerebral blood flow autoregulation in healthy adults

• Published in: Frontiers in physiology Vol. 13; p. 1015544
• Main Authors: Marmarelis, Vasilis Z., Shin, Dae C., Hamner, Jason W., Tan, Can Ozan
• Format: Journal Article
• Language: English
• Published: Frontiers Media S.A 02.11.2022
• Subjects: autonomic control; cerebral autoregulation; cerebral blood flow regulation; cholinergic mechanism; dynamic vasomotor reactivity; Physiology

Background: Cerebral flow autoregulation (CFA) is a homeostatic mechanism critical for survival. The autonomic nervous system (ANS) plays a key role in maintaining proper CFA function. More quantitative studies of how the ANS influences CFA are desirable. Objective: To discover and quantify the dyna...