Long-term outcome of bilateral pallidal deep brain stimulation for primary cervical dystonia

Ten patients with severe cervical dystonia (CD) unresponsive to medical treatment underwent bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) and were followed for 31.9 +/- 20.9 months. At last follow-up, the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) severity sc...

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Bibliographic Details
Published inNeurology Vol. 68; no. 6; p. 457
Main Authors Hung, S W, Hamani, C, Lozano, A M, Poon, Y-Y W, Piboolnurak, P, Miyasaki, J M, Lang, A E, Dostrovsky, J O, Hutchison, W D, Moro, E
Format Journal Article
LanguageEnglish
Published United States 06.02.2007
Subjects
Adult
Aged
Deep Brain Stimulation - methods
Female
Globus Pallidus
Humans
Longitudinal Studies
Male
Middle Aged
Torticollis - diagnosis
Torticollis - therapy
Treatment Outcome
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Summary:Ten patients with severe cervical dystonia (CD) unresponsive to medical treatment underwent bilateral globus pallidus internus (GPi) deep brain stimulation (DBS) and were followed for 31.9 +/- 20.9 months. At last follow-up, the Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) severity score improved by 54.8%, the TWSTRS disability score improved by 59.1%, and the TWSTRS pain score improved by 50.4%. Bilateral GPi DBS is an effective long-term therapy in patients with CD.
ISSN:1526-632X
DOI:10.1212/01.wnl.0000252932.71306.89