Feasibility of Harmonic Motion Imaging Using a Single Transducer: In Vivo Imaging of Breast Cancer in a Mouse Model and Human Subjects

• Published in: IEEE transactions on medical imaging Vol. 40; no. 5; pp. 1390 - 1404
• Main Authors: Hossain, Md Murad, Saharkhiz, Niloufar, Konofagou, Elisa E.
• Format: Journal Article
• Language: English
• Published: United States IEEE 01.05.2021; The Institute of Electrical and Electronics Engineers, Inc. (IEEE)
• Subjects: Acoustics; Animals; ARFI; Axis movements; Breast cancer; Breast Neoplasms - diagnostic imaging; Data acquisition; elasticity imaging; Elasticity Imaging Techniques; Excitation; Feasibility; Feasibility Studies; Female; Fibroadenoma; Harmonic analysis; Harmonic motion; Harmonic motion imaging; Harmonic oscillation; high-frequency ARF; Human motion; Humans; Hyperplasia; Imaging; Inclusions; Invasiveness; Mechanical factors; Mechanical properties; Medical imaging; Mice; Phantoms, Imaging; Pulse duration; Radiation; Research Subjects; Sound waves; Tissues; Tracking; Transducers; Tumor cells; Tumors; Ultrasonic imaging; Ultrasound
• ISSN: 0278-0062; 1558-254X; 1558-254X
• DOI: 10.1109/TMI.2021.3055779

Harmonic motion imaging (HMI) interrogates the mechanical properties of tissues by simultaneously generating and tracking harmonic oscillation using focused ultrasound and imaging transducers, respectively. Instead of using two transducers, the objective of this work is to develop a single transduce...