Competence of Combined Low Dose of Human Chorionic Gonadotropin (HCG) and Clomiphene Citrate (CC) Versus Continued CC during Ovulation Induction in Women with CC-Resistant Polycystic Ovarian Syndrome: A Randomized Controlled Trial

• Published in: Medicina (Kaunas, Lithuania) Vol. 60; no. 8; p. 1300
• Main Authors: Thabet, Mahmoud, Abdelhafez, Mohamed Sayed, Elshamy, Maged Ragheb, Albahlol, Ibrahim A., Fayala, Emad, Wageeh, Alaa, El-Zayadi, Ahmed Abdelhamid, Bahgat, Nagwan Ahmed, Mohammed, Shereen M., Mohamed, Alhussein Ahmed, Awad, Mahmoud Mohamed, El-Menayyer, Ahmed, El-Sherbiny, Mohamed, Elsherbini, Dalia Mahmoud Abdelmonem, Albarakati, Rayan G., Alshaikh, Ahmed Baker A., Edris, Fawaz E., Bushaqer, Nayla Jamal, Salama, Youstina Georges Makarious, Abdel-razik, Mahmoud Mohamed
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 12.08.2024; MDPI
• Subjects: Acne; Adult; Androgens; Body mass index; Chorionic Gonadotropin - administration & dosage; Chorionic Gonadotropin - blood; Chorionic Gonadotropin - therapeutic use; Clomiphene - administration & dosage; Clomiphene - therapeutic use; clomiphene citrate; clomiphene resistance; Diabetes; Estrogens; Female; Fertility Agents, Female - administration & dosage; Fertility Agents, Female - therapeutic use; Hair; human chorionic gonadotropin; Humans; Hypothalamus; Infertility; Infertility, Female - drug therapy; Infertility, Female - etiology; Insulin resistance; Menstruation; Ovaries; Ovulation; Ovulation Induction - methods; Pituitary gland; polycystic ovarian syndrome; Polycystic ovary syndrome; Polycystic Ovary Syndrome - complications; Polycystic Ovary Syndrome - drug therapy; Polycystic Ovary Syndrome - physiopathology; Pregnancy; Pregnancy Rate; Testosterone; Thyroid gland; Treatment Outcome; clomiphene citrate; clomiphene resistance; human chorionic gonadotropin; polycystic ovarian syndrome; ovulation
• ISSN: 1648-9144; 1010-660X; 1648-9144
• DOI: 10.3390/medicina60081300

Background and Objectives: Polycystic ovarian syndrome (PCOS) is a widespread endocrine disorder affecting 5–18% of females in their childbearing age. The aim of this study is to assess the efficacy of combining a low dosage of human chorionic gonadotropin (HCG) along with clomiphene citrate (CC) fo...