Methylation-associated silencing of miR-193a-3p promotes ovarian cancer aggressiveness by targeting GRB7 and MAPK/ERK pathways - Chen, Kangmei; Liu, Michelle Xin; Mak, Celia Sze-Ling; Yung, Mingo Ming-Ho; Leung, Thomas Ho-Yin; Xu, Dakang; Ngu, Siew-Fei; Chan, Karen Kar-Loen; Yang, Huijuan; Ngan, Hextan Yuen-Sheung; Chan, David Wai (Theranostics, 2018)
Keywords: Animals; Carcinogenesis - genetics; Cell Line, Tumor; Cell Movement - genetics; Cell Proliferation - genetics; Female; Gene Expression Regulation, Neoplastic - genetics; Gene Silencing - physiology; GRB7 Adaptor Protein - genetics; Humans; MAP Kinase Signaling System - genetics; Methylation; Mice; Mice, Inbred BALB C; Mice, Nude; MicroRNAs - genetics; Ovarian Neoplasms - genetics; Research Paper; RNA Interference - physiology; Signal Transduction - genetics; Up-Regulation - genetics; GRB7; DNA hypermethylation; ovarian cancer; miR-193a-3p; MAPK signaling