A natural approach to combating antibiotic-resistant pathogens in livestock: Hibiscus sabdariffa-derived hibiscus acid as a promising solution

• Published in: Veterinární medicína Vol. 69; no. 6; pp. 207 - 216
• Main Authors: Rangel-Vargas, E, Gomez-Aldapa, CA, Falfan-Cortes, RN, Guzman-Ortiz, FA, Rosas, JC
• Format: Journal Article
• Language: English
• Published: Czech Republic Czech Academy of Agricultural Sciences (CAAS) 01.06.2024; Czech Academy of Agricultural Sciences
• Subjects: Acid resistance; Acids; Antibiotic resistance; E coli; Feces; Group theory; Hibiscus sabdariffa; Inoculation; Livestock; Minimum inhibitory concentration; Multidrug resistance; Original Paper; Pathogens; plant antimicrobial agents; Roselle; Salmonella; salmonella typhimurium; shiga-toxin-producing escherichia coli; Streptomycin; synergistic effect; Toxins; Shiga-toxin-producing Escherichia coli; plant antimicrobial agents; Salmonella Typhimurium; synergistic effect

We examined the antibacterial efficacy of streptomycin, hibiscus acid, and their combination against multidrug-resistant Shiga-toxin-producing (STEC) and Typhimurium in mice. We determined the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) for streptomycin, hibis...