Upconverting nanoparticles for the near infrared photoactivation of transition metal complexes: new opportunities and challenges in medicinal inorganic photochemistry

The article highlights the emergent use of upconverting nanoparticles as tools for the near infrared photoactivation of transition metal complexes, identifying opportunities and challenges of this approach in the context of medicinal inorganic chemistry. The article highlights the emergent use of up...

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Published inDalton transactions : an international journal of inorganic chemistry Vol. 45; no. 33; pp. 1312 - 132
Main Authors Ruggiero, Emmanuel, Alonso-de Castro, Silvia, Habtemariam, Abraha, Salassa, Luca
Format Journal Article
LanguageEnglish
Published England 16.08.2016
Subjects
Animals
Coordination Complexes - administration & dosage
Coordination Complexes - chemistry
Coordination Complexes - radiation effects
Coordination compounds
Humans
Light
Nanoparticles
Nanoparticles - administration & dosage
Nanoparticles - chemistry
Nanoparticles - radiation effects
Photochemistry
Transition Elements - administration & dosage
Transition Elements - chemistry
Transition Elements - radiation effects
Transition metals
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Summary:The article highlights the emergent use of upconverting nanoparticles as tools for the near infrared photoactivation of transition metal complexes, identifying opportunities and challenges of this approach in the context of medicinal inorganic chemistry. The article highlights the emergent use of upconverting nanoparticles as tools for the near infrared photoactivation of transition metal complexes.
Bibliography:Dr Luca Salassa obtained his MSc degree and PhD from the University of Turin (Italy). After a postdoctoral position in Missoula (USA) at the University of Montana, he was awarded a Marie Curie IEF fellowship (2008) and joined Sadler's group at the University of Warwick (UK). In 2012, he moved to CIC biomaGUNE in San Sebastián (Spain) where he established his research group. Luca has recently been awarded an Ikerbasque Professorship.
Silvia Alonso de Castro obtained her BSc (2011) and MSc (2013) degrees in Applied Chemistry and Pharmacology at the Jaume I University (Castellón de la Plana, Spain). In her undergraduate thesis, she developed new tetrapeptidic hydrogels under the supervision of Dr Juan F. Miravet and studied their rheology in a joint project with P&G. Silvia joined Salassa's group in mid-2014 for her PhD on the development of upconverting nanomaterials for theranostics.
Dr Abraha Habtemariam obtained his BSc degree from the University of East Anglia and his PhD from the University of Sussex. After a post-doctoral fellowship at the University of Toronto (Canada), he joined Peter Sadler's group at Birkbeck College, University of London and in 1996 moved to the University of Edinburgh. In 2007 he moved to the University of Warwick as a Senior Research Fellow. He was Ikerbasque Visiting Professor at CIC biomaGUNE, San Sebastián, Spain (2013-2014).
Emmanuel Ruggiero was born in Naples (Italy) in 1987. He received his BSc (2009) and MSc (2011) degrees in Chemistry from the University of Naples Federico II. He then moved to Pisa as a research fellow of NEST-Scuola Normale Superiore where he worked on the synthesis of non-natural peptides. In 2013, he started his PhD under the supervision of Dr Luca Salassa at CIC biomaGUNE (Spain), where he is exploring the use of upconverting nanoparticles as tools for the near infrared photoactivation of metal-based prodrugs.
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ISSN:1477-9226
1477-9234
1477-9234
DOI:10.1039/c6dt01428c