Arabidopsis MRG domain proteins bridge two histone modifications to elevate expression of flowering genes

• Published in: Nucleic acids research Vol. 42; no. 17; pp. 10960 - 10974
• Main Authors: Xu, Yifeng, Gan, Eng-Seng, Zhou, Jie, Wee, Wan-Yi, Zhang, Xiaoyu, Ito, Toshiro
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 29.09.2014
• Subjects: Acetylation; Arabidopsis - genetics; Arabidopsis - growth & development; Arabidopsis Proteins - analysis; Arabidopsis Proteins - genetics; Arabidopsis Proteins - metabolism; Chromosomal Proteins, Non-Histone - analysis; Chromosomal Proteins, Non-Histone - genetics; Chromosomal Proteins, Non-Histone - metabolism; Euchromatin - chemistry; Flowers - genetics; Gene Expression Regulation, Plant; Gene regulation, Chromatin and Epigenetics; Histone Acetyltransferases - metabolism; Histone-Lysine N-Methyltransferase - metabolism; Histones - metabolism; MADS Domain Proteins - genetics; MADS Domain Proteins - metabolism; Mutation; Phenotype; Transcription, Genetic

Trimethylation of lysine 36 of histone H3 (H3K36me3) is found to be associated with various transcription events. In Arabidopsis, the H3K36me3 level peaks in the first half of coding regions, which is in contrast to the 3'-end enrichment in animals. The MRG15 family proteins function as 'r...