Interleukin (IL)–12, IL-2, and IL-6 Gene Polymorphisms in Takayasu’s Arteritis from Turkey

• Published in: Human Immunology Vol. 67; no. 9; pp. 735 - 740
• Main Authors: Saruhan-Direskeneli, G., Bıçakçıgil, M., Yılmaz, V., Kamalı, S., Aksu, K., Fresko, I., Akkoç, N., Kiraz, S., Özer, H.T.E., Tunç, E., Yücel, E., Karaarslan, Y., Uyar, F.A., Doganavşargil, E., Inanc, M., Direskeneli, H.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.09.2006
• Subjects: Adult; Female; Genetic Predisposition to Disease; Humans; IL12; IL2; IL6; Interleukin-12 - genetics; Interleukin-2 - genetics; Interleukin-6 - genetics; Male; Polymerase Chain Reaction; Polymorphism; Polymorphism, Genetic; Takayasu; Takayasu Arteritis - genetics; Turkey; Turkey; Takayasu; IL6; IL12; IL2; Polymorphism

Takayasu’s arteritis (TA) is a chronic arterial inflammation of unknown etiology involving mainly the aorta and its major branches. Genetic polymorphisms of cytokines are screened as susceptibility factors for TA in Turkey. A total of 94 patients with TA were investigated for the genetic polymorphis...