Naamines and Naamidines as Novel Agents against a Plant Virus and Phytopathogenic Fungi

• Published in: Marine drugs Vol. 16; no. 9; p. 311
• Main Authors: Guo, Pengbin, Li, Gang, Liu, Yuxiu, Lu, Aidang, Wang, Ziwen, Wang, Qingmin
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI 03.09.2018; MDPI AG
• Subjects: Alkaloids - chemical synthesis; Alkaloids - pharmacology; anti-tobacco mosaic virus (TMV) activity; Aquatic Organisms - chemistry; Drug Design; Fungi - drug effects; Fungi - pathogenicity; fungicidal activity; Fungicides, Industrial - chemical synthesis; Fungicides, Industrial - pharmacology; Imidazoles - chemical synthesis; Imidazoles - pharmacology; marine natural products; Molecular Structure; naamidines; naamines; Plant Diseases - microbiology; Plant Diseases - prevention & control; Structure-Activity Relationship; Tobacco Mosaic Virus - drug effects; Tobacco Mosaic Virus - pathogenicity; naamidines; anti-tobacco mosaic virus (TMV) activity; marine natural products; fungicidal activity; naamines

Naamines, naamidines and various derivatives of these marine natural products were synthesized and characterized by means of nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. The activities of these alkaloids against a plant virus and phytopathogenic fungi were evaluated for the f...