Pyroptosis, a new bridge to tumor immunity

• Published in: Cancer science Vol. 112; no. 10; pp. 3979 - 3994
• Main Authors: Li, Lisha, Jiang, Mingxia, Qi, Ling, Wu, Yiming, Song, Dongfeng, Gan, Junqing, Li, Yanjing, Bai, Yuxian
• Format: Journal Article
• Language: English
• Published: Tokyo John Wiley & Sons, Inc 01.10.2021; John Wiley and Sons Inc
• Subjects: Antigens; Apoptosis; cancer; Cancer therapies; Cell death; Cytokines; Homeostasis; immune; Immune checkpoint; immune microenvironment; Immune response; Immune system; Immunosurveillance; Immunotherapy; inflammasome; Inflammasomes; Microenvironments; Pathogens; PD-L1 protein; Pyroptosis; Review; Tumorigenesis; Tumors

Pyroptosis refers to the process of gasdermin (GSDM)‐mediated programmed cell death (PCD). Our understanding of pyroptosis has expanded beyond cells and is known to involve extracellular responses. Recently, there has been an increasing interest in pyroptosis due to its emerging role in activating t...