Interventional human ocular safety experiments for 222‐nm far‐ultraviolet‐C lamp irradiation

• Published in: Photochemistry and photobiology Vol. 101; no. 2; pp. 517 - 526
• Main Authors: Sugihara, Kazunobu, Kaidzu, Sachiko, Sasaki, Masahiro, Tanito, Masaki
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.03.2025; John Wiley and Sons Inc
• Subjects: 222‐nm excimer lamp; Acuity; Adult; Clinical significance; Clinical trials; Cornea; Damage; Discomfort; erythema; Excimers; Exposure; Eye; Eye (anatomy); Eye - radiation effects; Female; health hazard; Humans; Hyperemia; Irradiation; Lacrimal gland and Nasolacrimal duct; Male; Microorganisms; Middle Aged; photokeratitis; Prospective Studies; Radiation; Safety; Tears; ultraviolet germicidal irradiation (UVGI); Ultraviolet radiation; Ultraviolet Rays - adverse effects; Visual acuity; Visual Acuity - radiation effects; ultraviolet germicidal irradiation (UVGI); photokeratitis; 222‐nm excimer lamp; erythema; health hazard

The study aimed to directly assess the ocular safety of 222‐nm far‐ultraviolet‐C (UVC) irradiation in humans, given the limited clinical trials in this area. This wavelength offers the potential for safe and effective microbial inactivation in occupied spaces, but its safety profile for human eyes r...