Malignancies after mitoxantrone for multiple sclerosis: A retrospective cohort study

• Published in: Neurology Vol. 86; no. 23; p. 2203
• Main Authors: Buttmann, Mathias, Seuffert, Linda, Mäder, Uwe, Toyka, Klaus V
• Format: Journal Article
• Language: English
• Published: United States 07.06.2016
• Subjects: Adolescent; Adult; Aged; Female; Follow-Up Studies; Germany; Humans; Immunosuppressive Agents - adverse effects; Immunosuppressive Agents - therapeutic use; Incidence; Male; Middle Aged; Mitoxantrone - adverse effects; Mitoxantrone - therapeutic use; Multiple Sclerosis - drug therapy; Multiple Sclerosis - epidemiology; Neoplasms - epidemiology; Neoplasms - etiology; Registries; Retrospective Studies; Risk Factors; Young Adult

To assess the therapy-related risk of malignancies in mitoxantrone-treated patients with multiple sclerosis. This retrospective observational cohort study included all mitoxantrone-treated patients with multiple sclerosis seen at our department between 1994 and 2007. We collected follow-up informati...