Correlation of striatal dopamine D2/3 receptor availability with GABA level in the anterior cingulate cortex in healthy controls but not in alcohol‐dependent subjects and individuals at high risk: A multimodal magnetic resonance spectroscopy and positron emission tomography study - Spitta, Gianna; Gleich, Tobias; Rosenthal, Annika; Schubert, Florian; Aydin, Semiha; Heinz, Andreas; Buchert, Ralph; Gallinat, Jürgen (Addiction biology, 2024)
Keywords: Addictions; Adult; Alcohol; alcohol dependence; Alcoholism - diagnostic imaging; Alcoholism - metabolism; Benzamides; Case-Control Studies; Corpus Striatum - diagnostic imaging; Corpus Striatum - metabolism; Cortex (cingulate); Dopamine; Dopamine D2 receptors; dopamine D2/3 receptor; Drug dependence; Female; GABA; gamma-Aminobutyric Acid - metabolism; Glutamic Acid - metabolism; Gyrus Cinguli - diagnostic imaging; Gyrus Cinguli - metabolism; Humans; individuals at high risk; Magnetic Resonance Spectroscopy; Male; Mesolimbic system; Middle Aged; Neostriatum; Neurotransmission; Original; Positron emission tomography; Receptors, Dopamine D2 - metabolism; Receptors, Dopamine D3 - metabolism; Spectrum analysis; Tomography; γ-Aminobutyric acid; GABA; dopamine D2/3 receptor; magnetic resonance spectroscopy; positron emission tomography; alcohol dependence; individuals at high risk