Nanoparticles as delivery vehicles for antiviral therapeutic drugs

•Nearly any antiviral drug delivery system can be nanoscaled to the effect of improved properties.•Efficacy of drug delivery can be improved using nanoparticles as delivery vehicles.•Nanoparticulate antiviral drug delivery systems show promise in regards to treating the current COVID-19 pandemic.•Th...

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Published inEngineered regeneration Vol. 2; pp. 31 - 46
Main Authors Maus, Alexander, Strait, Lia, Zhu, Donghui
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 2021
The Authors. Publishing Services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd
KeAi Communications Co., Ltd
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ISSN2666-1381
2666-1381
DOI10.1016/j.engreg.2021.03.001

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Abstract •Nearly any antiviral drug delivery system can be nanoscaled to the effect of improved properties.•Efficacy of drug delivery can be improved using nanoparticles as delivery vehicles.•Nanoparticulate antiviral drug delivery systems show promise in regards to treating the current COVID-19 pandemic.•There are numerous public health and financial incentives for further advancement of the nanoparticulate antiviral field. With the ongoing COVID-19 pandemic still escalating, many researchers are turning to nanotechnology as a method of treatment not only for this pandemic, but in preparation for the pandemics of the future. Given both a wide variety of biomaterials at their disposal and the recent rise of nanotechnology, scientists now have the means to release and distribute therapeutic drugs in a variety of ways. Such a variety permits medical professionals the ability to choose biomaterials and methods that would provide the best release and treatment methodologies for the viral ailment they are attempting to remedy. This integrative review discusses context of previous pandemics, viral pathogenesis, issues associated with the current state of antiviral delivery systems, numerous biomaterials used for this purpose, and further information regarding the ongoing global COVID-19 pandemic. [Display omitted]
AbstractList With the ongoing COVID-19 pandemic still escalating, many researchers are turning to nanotechnology as a method of treatment not only for this pandemic, but in preparation for the pandemics of the future. Given both a wide variety of biomaterials at their disposal and the recent rise of nanotechnology, scientists now have the means to release and distribute therapeutic drugs in a variety of ways. Such a variety permits medical professionals the ability to choose biomaterials and methods that would provide the best release and treatment methodologies for the viral ailment they are attempting to remedy. This integrative review discusses context of previous pandemics, viral pathogenesis, issues associated with the current state of antiviral delivery systems, numerous biomaterials used for this purpose, and further information regarding the ongoing global COVID-19 pandemic.
With the ongoing COVID-19 pandemic still escalating, many researchers are turning to nanotechnology as a method of treatment not only for this pandemic, but in preparation for the pandemics of the future. Given both a wide variety of biomaterials at their disposal and the recent rise of nanotechnology, scientists now have the means to release and distribute therapeutic drugs in a variety of ways. Such a variety permits medical professionals the ability to choose biomaterials and methods that would provide the best release and treatment methodologies for the viral ailment they are attempting to remedy. This integrative review discusses context of previous pandemics, viral pathogenesis, issues associated with the current state of antiviral delivery systems, numerous biomaterials used for this purpose, and further information regarding the ongoing global COVID-19 pandemic.With the ongoing COVID-19 pandemic still escalating, many researchers are turning to nanotechnology as a method of treatment not only for this pandemic, but in preparation for the pandemics of the future. Given both a wide variety of biomaterials at their disposal and the recent rise of nanotechnology, scientists now have the means to release and distribute therapeutic drugs in a variety of ways. Such a variety permits medical professionals the ability to choose biomaterials and methods that would provide the best release and treatment methodologies for the viral ailment they are attempting to remedy. This integrative review discusses context of previous pandemics, viral pathogenesis, issues associated with the current state of antiviral delivery systems, numerous biomaterials used for this purpose, and further information regarding the ongoing global COVID-19 pandemic.
With the ongoing COVID-19 pandemic still escalating, many researchers are turning to nanotechnology as a method of treatment not only for this pandemic, but in preparation for the pandemics of the future. Given both a wide variety of biomaterials at their disposal and the recent rise of nanotechnology, scientists now have the means to release and distribute therapeutic drugs in a variety of ways. Such a variety permits medical professionals the ability to choose biomaterials and methods that would provide the best release and treatment methodologies for the viral ailment they are attempting to remedy. This integrative review discusses context of previous pandemics, viral pathogenesis, issues associated with the current state of antiviral delivery systems, numerous biomaterials used for this purpose, and further information regarding the ongoing global COVID-19 pandemic. Image, graphical abstract
•Nearly any antiviral drug delivery system can be nanoscaled to the effect of improved properties.•Efficacy of drug delivery can be improved using nanoparticles as delivery vehicles.•Nanoparticulate antiviral drug delivery systems show promise in regards to treating the current COVID-19 pandemic.•There are numerous public health and financial incentives for further advancement of the nanoparticulate antiviral field. With the ongoing COVID-19 pandemic still escalating, many researchers are turning to nanotechnology as a method of treatment not only for this pandemic, but in preparation for the pandemics of the future. Given both a wide variety of biomaterials at their disposal and the recent rise of nanotechnology, scientists now have the means to release and distribute therapeutic drugs in a variety of ways. Such a variety permits medical professionals the ability to choose biomaterials and methods that would provide the best release and treatment methodologies for the viral ailment they are attempting to remedy. This integrative review discusses context of previous pandemics, viral pathogenesis, issues associated with the current state of antiviral delivery systems, numerous biomaterials used for this purpose, and further information regarding the ongoing global COVID-19 pandemic. [Display omitted]
Author Maus, Alexander
Strait, Lia
Zhu, Donghui
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2021 The Authors. Publishing Services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. 2021
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Keywords COVID-19
Antiviral
Drug selivery
Nanotechnology
Language English
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Snippet •Nearly any antiviral drug delivery system can be nanoscaled to the effect of improved properties.•Efficacy of drug delivery can be improved using...
With the ongoing COVID-19 pandemic still escalating, many researchers are turning to nanotechnology as a method of treatment not only for this pandemic, but in...
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SubjectTerms Antiviral
COVID-19
Drug selivery
Nanotechnology
Title Nanoparticles as delivery vehicles for antiviral therapeutic drugs
URI https://dx.doi.org/10.1016/j.engreg.2021.03.001
https://www.ncbi.nlm.nih.gov/pubmed/38620592
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