N‐acetylcysteine reduces cocaine‐seeking behavior and anterior cingulate glutamate/glutamine levels among cocaine‐dependent individuals - Woodcock, Eric A.; Lundahl, Leslie H.; Khatib, Dalal; Stanley, Jeffrey A.; Greenwald, Mark K. (Addiction biology, 2021)
Keywords: Acetylcysteine; Acetylcysteine - pharmacology; Acetylcysteine - therapeutic use; Adult; anterior cingulate cortex; Blindness; Cocaine; Cocaine-Related Disorders - drug therapy; Cross-Over Studies; Double-Blind Method; Drug-Seeking Behavior - drug effects; drug‐seeking behavior; Female; glutamate; Glutamic Acid - drug effects; Glutamine; Glutamine - drug effects; Gyrus Cinguli - drug effects; Humans; Magnetic resonance spectroscopy; Male; Middle Aged; N‐acetylcysteine; Placebos; Proton Magnetic Resonance Spectroscopy; Reinstatement; relapse; Reward; drug-seeking behavior; cocaine; relapse; anterior cingulate cortex; glutamate; N-acetylcysteine