SLMP53-1 interacts with wild-type and mutant p53 DNA-binding domain and reactivates multiple hotspot mutations - Gomes, Ana Sara; Ramos, Helena; Gomes, Sara; Loureiro, Joana B.; Soares, Joana; Barcherini, Valentina; Monti, Paola; Fronza, Gilberto; Oliveira, Carla; Domingues, Lucília; Bastos, Margarida; Dourado, Daniel F.A.R.; et al. (Biochimica et biophysica acta. General subjects, 2020)
Keywords: antineoplastic activity; Cancer; chemical interactions; Chemotherapy; DNA; DNA-binding domains; humans; Mutant; mutants; mutation; neoplasm cells; neoplasms; p53; patients; proteins; Reactivator; therapeutics; thermal stability; yeasts; CETSA; Chemotherapy; SRB; mutp53; Mutant; DBD; Reactivator; wt; p53; Cancer