Chest compression release velocity factors during out-of-hospital cardiac resuscitation
Higher chest compression release velocity (CCRV) has been associated with better outcomes after out-of-hospital cardiac arrest (OHCA), and patient factors have been associated with variations in chest wall compliance and compressibility. We evaluated whether patient sex, age, weight, and time in res...
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Published in | Resuscitation Vol. 145; pp. 37 - 42 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
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Elsevier B.V
01.12.2019
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ISSN | 0300-9572 1873-1570 1873-1570 |
DOI | 10.1016/j.resuscitation.2019.09.024 |
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Abstract | Higher chest compression release velocity (CCRV) has been associated with better outcomes after out-of-hospital cardiac arrest (OHCA), and patient factors have been associated with variations in chest wall compliance and compressibility. We evaluated whether patient sex, age, weight, and time in resuscitation were associated with CCRV during pre-hospital resuscitation from OHCA.
Observational study of prospectively collected OHCA quality improvement data in two suburban EMS agencies in Arizona between 10/1/2008 and 12/31/2016. Subject-level mean CCRV during the first 10 min of compressions was correlated with categorical variables by the Wilcoxon rank-sum test and with continuous variables by the Spearman’s rank correlation coefficient. Generalized estimating equation and linear mixed-effect models were used to study the trend of CCRV over time.
During the study period, 2535 adult OHCA cases were treated. After exclusion criteria, 1140 cases remained for analysis. Median duration of recorded compressions was 8.70 min during the first 10 min of CPR. An overall decline in CCRV was observed even after adjusting for compression depth. The subject-level mean CCRV was higher for minutes 0–5 than for minutes 5–10 (mean 347.9 mm/s vs. 339.0 mm/s, 95% CI of the difference −12.4 to −5.4, p < 0.0001). Males exhibited a greater mean CCRV compared to females [344.4 mm/s (IQR 307.3–384.6) vs. 331.5 mm/s (IQR 285.3–385.5), p = 0.013]. Mean CCRV was negatively correlated with age and positively correlated with patient weight.
CCRV declines significantly over the course of resuscitation. Patient characteristics including male sex, younger age, and increased weight were associated with a higher CCRV. |
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AbstractList | Higher chest compression release velocity (CCRV) has been associated with better outcomes after out-of-hospital cardiac arrest (OHCA), and patient factors have been associated with variations in chest wall compliance and compressibility. We evaluated whether patient sex, age, weight, and time in resuscitation were associated with CCRV during pre-hospital resuscitation from OHCA.
Observational study of prospectively collected OHCA quality improvement data in two suburban EMS agencies in Arizona between 10/1/2008 and 12/31/2016. Subject-level mean CCRV during the first 10 min of compressions was correlated with categorical variables by the Wilcoxon rank-sum test and with continuous variables by the Spearman’s rank correlation coefficient. Generalized estimating equation and linear mixed-effect models were used to study the trend of CCRV over time.
During the study period, 2535 adult OHCA cases were treated. After exclusion criteria, 1140 cases remained for analysis. Median duration of recorded compressions was 8.70 min during the first 10 min of CPR. An overall decline in CCRV was observed even after adjusting for compression depth. The subject-level mean CCRV was higher for minutes 0–5 than for minutes 5–10 (mean 347.9 mm/s vs. 339.0 mm/s, 95% CI of the difference −12.4 to −5.4, p < 0.0001). Males exhibited a greater mean CCRV compared to females [344.4 mm/s (IQR 307.3–384.6) vs. 331.5 mm/s (IQR 285.3–385.5), p = 0.013]. Mean CCRV was negatively correlated with age and positively correlated with patient weight.
CCRV declines significantly over the course of resuscitation. Patient characteristics including male sex, younger age, and increased weight were associated with a higher CCRV. Higher chest compression release velocity (CCRV) has been associated with better outcomes after out-of-hospital cardiac arrest (OHCA), and patient factors have been associated with variations in chest wall compliance and compressibility. We evaluated whether patient sex, age, weight, and time in resuscitation were associated with CCRV during pre-hospital resuscitation from OHCA. Observational study of prospectively collected OHCA quality improvement data in two suburban EMS agencies in Arizona between 10/1/2008 and 12/31/2016. Subject-level mean CCRV during the first 10 min of compressions was correlated with categorical variables by the Wilcoxon rank-sum test and with continuous variables by the Spearman's rank correlation coefficient. Generalized estimating equation and linear mixed-effect models were used to study the trend of CCRV over time. During the study period, 2535 adult OHCA cases were treated. After exclusion criteria, 1140 cases remained for analysis. Median duration of recorded compressions was 8.70 min during the first 10 min of CPR. An overall decline in CCRV was observed even after adjusting for compression depth. The subject-level mean CCRV was higher for minutes 0-5 than for minutes 5-10 (mean 347.9 mm/s vs. 339.0 mm/s, 95% CI of the difference -12.4 to -5.4, p < 0.0001). Males exhibited a greater mean CCRV compared to females [344.4 mm/s (IQR 307.3-384.6) vs. 331.5 mm/s (IQR 285.3-385.5), p = 0.013]. Mean CCRV was negatively correlated with age and positively correlated with patient weight. CCRV declines significantly over the course of resuscitation. Patient characteristics including male sex, younger age, and increased weight were associated with a higher CCRV. Higher chest compression release velocity (CCRV) has been associated with better outcomes after out-of-hospital cardiac arrest (OHCA), and patient factors have been associated with variations in chest wall compliance and compressibility. We evaluated whether patient sex, age, weight, and time in resuscitation were associated with CCRV during pre-hospital resuscitation from OHCA.BACKGROUNDHigher chest compression release velocity (CCRV) has been associated with better outcomes after out-of-hospital cardiac arrest (OHCA), and patient factors have been associated with variations in chest wall compliance and compressibility. We evaluated whether patient sex, age, weight, and time in resuscitation were associated with CCRV during pre-hospital resuscitation from OHCA.Observational study of prospectively collected OHCA quality improvement data in two suburban EMS agencies in Arizona between 10/1/2008 and 12/31/2016. Subject-level mean CCRV during the first 10 min of compressions was correlated with categorical variables by the Wilcoxon rank-sum test and with continuous variables by the Spearman's rank correlation coefficient. Generalized estimating equation and linear mixed-effect models were used to study the trend of CCRV over time.METHODSObservational study of prospectively collected OHCA quality improvement data in two suburban EMS agencies in Arizona between 10/1/2008 and 12/31/2016. Subject-level mean CCRV during the first 10 min of compressions was correlated with categorical variables by the Wilcoxon rank-sum test and with continuous variables by the Spearman's rank correlation coefficient. Generalized estimating equation and linear mixed-effect models were used to study the trend of CCRV over time.During the study period, 2535 adult OHCA cases were treated. After exclusion criteria, 1140 cases remained for analysis. Median duration of recorded compressions was 8.70 min during the first 10 min of CPR. An overall decline in CCRV was observed even after adjusting for compression depth. The subject-level mean CCRV was higher for minutes 0-5 than for minutes 5-10 (mean 347.9 mm/s vs. 339.0 mm/s, 95% CI of the difference -12.4 to -5.4, p < 0.0001). Males exhibited a greater mean CCRV compared to females [344.4 mm/s (IQR 307.3-384.6) vs. 331.5 mm/s (IQR 285.3-385.5), p = 0.013]. Mean CCRV was negatively correlated with age and positively correlated with patient weight.RESULTSDuring the study period, 2535 adult OHCA cases were treated. After exclusion criteria, 1140 cases remained for analysis. Median duration of recorded compressions was 8.70 min during the first 10 min of CPR. An overall decline in CCRV was observed even after adjusting for compression depth. The subject-level mean CCRV was higher for minutes 0-5 than for minutes 5-10 (mean 347.9 mm/s vs. 339.0 mm/s, 95% CI of the difference -12.4 to -5.4, p < 0.0001). Males exhibited a greater mean CCRV compared to females [344.4 mm/s (IQR 307.3-384.6) vs. 331.5 mm/s (IQR 285.3-385.5), p = 0.013]. Mean CCRV was negatively correlated with age and positively correlated with patient weight.CCRV declines significantly over the course of resuscitation. Patient characteristics including male sex, younger age, and increased weight were associated with a higher CCRV.CONCLUSIONCCRV declines significantly over the course of resuscitation. Patient characteristics including male sex, younger age, and increased weight were associated with a higher CCRV. |
Author | Bobrow, Bentley Hu, Chengcheng Spaite, Daniel W. Vadeboncoeur, Tyler Silver, Annemarie Beger, Samuel Sutter, John |
Author_xml | – sequence: 1 givenname: Samuel surname: Beger fullname: Beger, Samuel email: sbeger@email.arizona.edu organization: The University of Arizona College of Medicine — Phoenix, Phoenix, AZ, United States – sequence: 2 givenname: John surname: Sutter fullname: Sutter, John email: johnsutter@email.arizona.edu organization: The University of Arizona College of Medicine — Phoenix, Phoenix, AZ, United States – sequence: 3 givenname: Tyler surname: Vadeboncoeur fullname: Vadeboncoeur, Tyler email: Vadeboncoeur.tyler@mayo.edu organization: Mayo Clinic, Jacksonville, FL, United States – sequence: 4 givenname: Annemarie surname: Silver fullname: Silver, Annemarie email: Asilver@zoll.com organization: ZOLL Medical Corporation, Chelmsford, MA, United States – sequence: 5 givenname: Chengcheng surname: Hu fullname: Hu, Chengcheng email: hucc@email.arizona.edu organization: The University of Arizona College of Medicine — Phoenix, Phoenix, AZ, United States – sequence: 6 givenname: Daniel W. surname: Spaite fullname: Spaite, Daniel W. email: dan@aemrc.arizona.edu organization: Arizona Department of Health Services, Phoenix, AZ, United States – sequence: 7 givenname: Bentley surname: Bobrow fullname: Bobrow, Bentley email: Bentley.Bobrow@azdhs.gov organization: The University of Arizona College of Medicine — Phoenix, Phoenix, AZ, United States |
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CitedBy_id | crossref_primary_10_1080_08998280_2020_1805840 crossref_primary_10_1016_j_ajem_2022_01_053 crossref_primary_10_1016_j_resplu_2022_100242 crossref_primary_10_1097_MCC_0000000000000726 crossref_primary_10_1016_j_aucc_2021_09_009 crossref_primary_10_1161_JAHA_123_033974 crossref_primary_10_1016_j_resuscitation_2021_08_036 crossref_primary_10_3389_fphys_2019_01475 crossref_primary_10_1016_j_resplu_2025_100867 crossref_primary_10_1109_JTEHM_2024_3429422 |
Cites_doi | 10.1161/CIR.0000000000000366 10.1016/j.actbio.2007.06.008 10.1016/j.resuscitation.2004.10.007 10.1016/j.forsciint.2004.04.086 10.1016/S0735-6757(02)42250-4 10.1016/j.amjmed.2005.11.014 10.1115/1.2894121 10.1016/S0300-9572(11)70147-2 10.1016/j.resuscitation.2014.10.020 10.1001/jama.299.10.1158 10.1016/j.resuscitation.2004.08.009 10.1016/j.resuscitation.2007.02.015 10.1161/CIR.0000000000000259 10.1152/jappl.1965.20.6.1211 10.1016/j.resuscitation.2015.05.002 10.1161/01.CIR.0000162503.57657.FA 10.1152/jappl.1987.62.6.2212 10.1016/j.resuscitation.2015.04.026 10.1016/j.resuscitation.2017.04.032 10.2147/ciia.2006.1.3.253 10.1016/j.resuscitation.2006.07.017 10.1016/j.resuscitation.2013.10.002 10.1016/j.resuscitation.2011.07.011 |
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Keywords | CPR Emergency medicine Cardiac arrest EMS Compressions Chest compressions OHCA Chest compression release velocity Feedback Out of hospital cardiac arrest Haemodynamics CCRV Resuscitation |
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Snippet | Higher chest compression release velocity (CCRV) has been associated with better outcomes after out-of-hospital cardiac arrest (OHCA), and patient factors have... |
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SubjectTerms | Cardiac arrest CCRV Chest compression release velocity Chest compressions Compressions CPR Emergency medicine EMS Feedback Haemodynamics OHCA Out of hospital cardiac arrest Resuscitation |
Title | Chest compression release velocity factors during out-of-hospital cardiac resuscitation |
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